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chr9:126,844,856-128,824,378

Best TWAS P=4.94e-12 · Best GWAS P=7.28e-12 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	PPP6C	0.06	0.10	lasso	3	0.07	3.2e-06	5.3	-5.3	1.3e-07	0.70	0.96	0.03	FALSE
2	GTEx	Artery Aorta	PRPS1P2	0.08	0.10	lasso	4	0.08	2.1e-05	-4.4	5.3	1.2e-07	-0.82	0.06	0.89	FALSE
3	GTEx	Artery Tibial	GAPVD1	0.11	0.16	enet	19	0.16	6.4e-13	-6.4	-6.8	7.4e-12	0.96	0.02	0.98	FALSE
4	GTEx	Artery Tibial	PRPS1P2	0.06	0.06	enet	6	0.05	9.2e-05	5.2	5.3	1.5e-07	-0.60	0.88	0.09	FALSE
5	GTEx	Brain Cerebellum	PRPS1P2	0.09	0.08	enet	16	0.04	2.8e-02	-6.8	6.1	1.3e-09	-0.82	0.05	0.80	FALSE
6	GTEx	Breast Mammary Tissue (Male)	PPP6C	0.12	0.03	enet	12	0.03	6.5e-02	5.2	-5.2	2.3e-07	0.59	0.07	0.10	FALSE
7	GTEx	Breast Mammary Tissue (Female)	PPP6C	0.14	0.04	lasso	4	0.04	3.1e-02	5.2	-5.7	1.4e-08	0.69	0.08	0.80	FALSE
8	GTEx	Cells Transformed fibroblasts	PRPS1P2	0.09	0.11	enet	8	0.13	9.6e-10	5.3	5.2	2.0e-07	-0.59	0.96	0.04	FALSE
9	GTEx	Colon Transverse	PRPS1P2	0.11	0.10	lasso	1	0.08	1.8e-04	5.3	5.3	8.8e-08	-0.63	0.64	0.04	FALSE
10	GTEx	Esophagus Mucosa	PPP6C	0.07	0.07	enet	21	0.08	7.1e-06	5.2	-5.6	2.1e-08	0.62	0.97	0.02	FALSE
11	GTEx	Esophagus Mucosa	PRPS1P2	0.07	0.08	lasso	3	0.07	1.5e-05	5.3	5.6	2.5e-08	-0.61	0.51	0.41	FALSE
12	GTEx	Esophagus Muscularis	OLFML2A	0.08	0.00	enet	27	0.00	4.9e-01	5.1	5.8	5.3e-09	-0.47	0.08	0.25	FALSE
13	GTEx	Muscle Skeletal	GAPVD1	0.13	0.10	lasso	3	0.09	4.7e-09	-6.8	6.8	9.5e-12	-0.99	0.02	0.98	FALSE
14	GTEx	Nerve Tibial	GAPVD1	0.17	0.08	lasso	10	0.10	9.3e-08	5.2	-6.4	1.3e-10	0.83	0.14	0.86	FALSE
15	GTEx	Pancreas	PRPS1P2	0.16	0.13	lasso	6	0.12	8.7e-06	5.2	5.3	9.0e-08	-0.61	0.88	0.08	FALSE
16	GTEx	Skin Sun Exposed Lower leg	GAPVD1	0.04	0.01	lasso	4	0.01	3.8e-02	5.2	-5.5	2.9e-08	0.74	0.21	0.68	FALSE
17	GTEx	Thyroid	GAPVD1	0.05	0.05	enet	13	0.01	6.6e-02	-6.7	-6.9	4.9e-12	0.99	0.02	0.98	TRUE
18	GTEx	Thyroid	PRPS1P2	0.08	0.09	enet	18	0.07	4.0e-06	5.2	5.3	1.1e-07	-0.67	0.92	0.08	FALSE
19	YFS	Blood	RABEPK	0.12	0.21	bslmm	317	0.22	2.4e-71	5.3	-5.2	1.7e-07	0.60	0.99	0.01	FALSE
20	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PPP6C	0.07	0.08	lasso	3	0.09	5.4e-10	5.3	-5.2	1.6e-07	0.62	0.02	0.98	FALSE
21	The Cancer Genome Atlas	Brain Lower Grade Glioma	PPP6C	0.02	0.02	lasso	2	0.01	1.5e-02	5.3	-5.3	1.5e-07	0.63	0.02	0.68	FALSE
22	The Cancer Genome Atlas	Lung Adenocarcinoma	PPP6C	0.02	0.02	lasso	4	0.02	7.6e-04	5.2	-5.2	1.5e-07	0.61	0.02	0.96	FALSE
23	The Cancer Genome Atlas	Prostate Adenocarcinoma	GAPVD1	0.02	0.04	enet	4	0.01	9.8e-03	-6.8	6.8	8.1e-12	-0.95	0.02	0.91	FALSE
24	The Cancer Genome Atlas	Thyroid Carcinoma	PPP6C	0.08	0.13	enet	9	0.13	5.5e-13	5.2	-5.1	2.7e-07	0.63	0.03	0.97	FALSE