Best TWAS P=6.34e-08 · Best GWAS P=4.16e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | KIAA1598 | 0.07 | 0.02 | lasso | 2 | 0.02 | 5.1e-03 | 5.0 | 5.3 | 1.1e-07 | 0.95 | 0.03 | 0.97 | FALSE |
| 2 | GTEx | Thyroid | KIAA1598 | 0.08 | 0.07 | lasso | 1 | 0.06 | 4.1e-05 | 5.4 | -5.4 | 6.3e-08 | -0.95 | 0.01 | 0.99 | TRUE |
| 3 | YFS | Blood | KIAA1598 | 0.39 | 0.64 | enet | 21 | 0.64 | 1.0e-279 | 5.0 | 5.2 | 2.0e-07 | 0.97 | 0.05 | 0.95 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | KIAA1598 | 0.04 | 0.04 | enet | 6 | 0.06 | 2.1e-07 | 5.2 | 5.2 | 2.1e-07 | 0.93 | 0.03 | 0.96 | FALSE |