Best TWAS P=2.37e-08 · Best GWAS P=5.18e-08 conditioned to 0.00746
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Gastroesophageal Junction | FAM45A | 0.24 | 0.13 | enet | 51 | 0.09 | 0.00027 | 3.9 | 5.6 | 2.4e-08 | 0.14 | 0.14 | 0.06 | TRUE |
| 2 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | C10orf46 | 0.23 | 0.04 | lasso | 4 | 0.04 | 0.00856 | -4.8 | 5.4 | 5.3e-08 | 0.41 | 0.02 | 0.11 | TRUE |