Hub : Genes

KIAA1598

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.2780	0.0650	3.2e-05	0.049	NA	0.038	NA	0.043	1.0e-03	NA	3.6e-03	NA	2.0e-03
2	GTEx	Artery Tibial	0.0696	0.0310	7.5e-03	0.025	NA	0.009	NA	0.024	4.7e-03	NA	6.4e-02	NA	5.1e-03
3	GTEx	Cells Transformed fibroblasts	0.1990	0.0480	3.2e-08	0.211	NA	0.215	NA	0.215	8.5e-16	NA	4.7e-16	NA	4.4e-16
4	GTEx	Lung	0.0979	0.0371	2.1e-03	0.097	NA	0.087	NA	0.094	7.3e-08	NA	3.7e-07	NA	1.2e-07
5	GTEx	Spleen	0.2750	0.0920	6.8e-03	-0.007	NA	-0.003	NA	-0.010	5.2e-01	NA	3.8e-01	NA	7.5e-01
6	GTEx	Thyroid	0.0790	0.0310	3.0e-03	0.072	NA	0.032	NA	0.056	3.5e-06	NA	1.6e-03	NA	4.1e-05
7	GTEx	Whole Blood	0.2650	0.0500	4.0e-12	0.219	NA	0.201	NA	0.208	6.3e-20	NA	2.8e-18	NA	5.7e-19
8	METSIM	Adipose	0.0676	0.0164	1.5e-10	0.106	0.073	0.092	0.083	0.098	1.3e-15	5.1e-11	1.3e-13	2.0e-12	2.0e-14
9	NTR	Blood	0.1159	0.0173	0.0e+00	0.196	0.150	0.186	0.143	0.190	4.5e-61	5.1e-46	8.1e-58	7.9e-44	3.3e-59
10	YFS	Blood	0.3894	0.0283	0.0e+00	0.635	0.610	0.637	0.634	0.634	1.7e-278	4.9e-260	1.0e-279	1.9e-277	9.1e-278
11	TCGA	Breast Invasive Carcinoma	0.0110	0.0062	1.7e-03	0.005	0.009	0.008	NA	0.005	2.3e-02	4.8e-03	8.0e-03	NA	2.4e-02
12	TCGA	Colon Adenocarcinoma	0.1350	0.0580	1.7e-04	0.073	0.029	0.033	NA	0.056	4.8e-05	8.7e-03	5.3e-03	NA	3.7e-04
13	TCGA	Head and Neck Squamous Cell Carcinoma	0.0244	0.0117	1.7e-04	0.033	0.036	0.040	NA	0.037	1.2e-04	6.3e-05	2.4e-05	NA	5.1e-05
14	TCGA	Lung Squamous Cell Carcinoma	0.0369	0.0159	1.0e-06	0.044	0.056	0.060	NA	0.058	7.8e-06	5.4e-07	2.1e-07	NA	3.8e-07
15	TCGA	Stomach Adenocarcinoma	0.0460	0.0330	7.0e-03	0.029	0.013	0.016	NA	0.014	3.2e-03	3.4e-02	2.2e-02	NA	3.4e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Bipolar Disorder (2018)	2.7	4.3	8.5	2.1	2.0	1.7	2.2	2.0	-1.7	2.3	2.1	1.9	2.1	1.9	1.7	2.2	1.9	2.9
Bipolar Disorder or Schizophrenia	0.5	1.3	2.7	1.1	1.0	0.8	1.1	1.2	-0.9	1.2	1.2	1.1	1.1	1.6	0.7	1.4	1.2	1.2
Depressed Affect (Nagel 2018)	1.6	3.4	7.4	2.0	1.6	1.5	1.6	2.7	-1.6	1.7	1.7	1.5	1.7	1.9	1.8	1.7	1.9	2.1
Depression (Nagel 2018)	1.9	2.8	4.8	1.5	1.5	1.4	1.7	2.2	-1.3	1.6	1.6	1.5	1.6	2.1	1.6	2.0	2.0	1.3
Intelligence (Savage-Jansen 2018)	0.8	2.6	5.6	0.1	1.8	1.1	1.9	2.4	-1.2	1.8	1.8	2.0	1.8	1.9	0.6	1.8	1.3	0.9
Neuroticism (Nagel 2018)	0.2	0.5	3.9	0.1	-0.4	-0.2	-0.6	2.0	0.9	-0.6	-0.8	-0.7	-0.6	0.1	0.1	-0.2	-0.1	0.5
Schizophrenia (2018)	0.1	0.1	0.6	-0.3	-0.3	-0.3	-0.4	-0.0	0.2	-0.4	-0.3	-0.1	-0.3	0.6	-0.4	-0.0	0.1	-0.8
Schizophrenia vs Biploar Disorder	0.7	0.9	2.6	-1.0	-1.1	-0.4	-0.9	-1.6	0.7	-1.1	-1.1	-0.9	-1.0	-0.6	-1.4	-0.7	-0.6	0.0
Worry (Nagel 2018)	2.7	5.7	9.5	-1.6	-2.5	-2.3	-2.8	0.4	2.9	-2.8	-3.1	-2.7	-2.8	-2.0	-2.0	-2.3	-2.6	-1.6
Alzheimer’s Disease (in mother)	0.4	0.5	2.0	0.5	-0.2	-1.2	-0.4	-0.4	0.5	-0.3	-0.3	-0.3	-0.3	-1.4	-0.7	-1.1	-1.1	-0.5
Alzheimer’s Disease (in father)	3.4	3.7	5.7	-1.1	-1.7	-2.4	-1.7	-2.2	2.1	-1.7	-1.7	-1.8	-1.8	-2.2	-2.1	-1.9	-2.1	-1.9
Alzheimer’s Disease (including proxy)	2.8	4.0	6.8	-0.9	-1.7	-2.6	-1.8	-2.2	1.9	-1.8	-1.8	-1.8	-1.8	-2.4	-2.5	-2.2	-2.3	-1.6
Crohns Disease (2017)	2.4	5.2	6.3	-1.6	-2.5	-2.3	-2.4	-2.3	2.5	-2.5	-2.3	-2.4	-2.4	-2.3	-1.8	-2.5	-2.4	-2.0
Irritable Bowel Disease (IBD)	2.7	6.5	9.1	-1.7	-2.8	-2.3	-2.6	-3.0	2.5	-2.6	-2.4	-2.7	-2.7	-2.8	-2.7	-2.8	-2.9	-1.6
Ulcerative Colitis (UC)	2.1	3.9	8.0	-1.1	-2.2	-1.6	-1.9	-2.3	1.7	-1.8	-1.7	-2.0	-2.0	-2.3	-2.8	-2.2	-2.3	-1.0
Major Depression (MDD)	0.6	0.7	1.5	0.4	0.8	0.9	0.8	0.7	-0.5	0.7	0.7	0.6	0.8	1.2	1.2	1.0	0.9	1.2
Reaction Time	0.1	0.1	0.9	1.0	-0.0	-0.5	-0.0	-0.2	0.1	0.0	-0.0	0.1	0.1	0.1	-0.1	-0.1	0.2	-0.4
Verbal and Numeric Reasoning (VNR)	0.0	0.1	0.3	-0.0	0.2	0.2	0.1	0.3	0.2	0.0	-0.1	0.2	-0.0	0.5	-0.1	0.4	-0.0	0.5
Breast Cancer	0.1	0.3	1.7	-1.3	-0.2	-0.4	0.1	-0.3	0.2	0.2	0.3	-0.1	0.1	-0.3	0.6	-0.3	-0.6	-1.2
Ovarian Cancer	0.1	0.1	0.5	-0.4	-0.0	-0.2	-0.4	-0.7	-0.1	-0.3	-0.2	-0.2	-0.2	-0.0	0.3	-0.2	-0.4	-0.3
Prostate Cancer	0.2	0.3	2.1	-0.0	-0.8	-0.2	-0.5	0.2	0.3	-0.4	-0.1	-0.5	-0.3	-0.0	-1.1	-0.3	-0.2	-1.5
Age at First Birth	8.7	12.7	21.0	-2.9	-3.7	-3.7	-3.4	-3.1	3.4	-3.2	-3.4	-3.7	-3.4	-4.0	-3.3	-3.8	-3.5	-4.6
Bipolar Disorder (2011)	0.5	0.5	1.1	-0.7	-0.9	-0.7	-0.9	-0.0	1.0	-1.0	-0.9	-0.8	-0.7	-0.3	0.0	-0.6	-0.5	0.0
Body Mass Index (BMI) (2010)	7.6	10.4	12.8	3.0	3.6	2.7	3.3	3.2	-3.3	3.3	3.1	3.5	3.4	3.3	2.9	3.3	2.9	3.5
Coronary Artery Disease (CAD)	0.1	0.1	0.8	0.0	0.1	0.3	0.1	-0.6	-0.2	0.1	0.2	0.3	0.1	0.0	0.0	-0.2	0.1	0.9
Crohns Disease (2012)	0.1	0.1	0.4	0.4	-0.3	0.1	0.0	-0.3	0.6	-0.2	-0.1	-0.2	-0.3	-0.5	-0.2	-0.1	-0.0	0.0
Mean Putamen Volume	8.5	9.8	13.7	1.7	3.4	3.2	3.4	3.2	-3.2	3.2	3.1	3.6	3.4	3.7	1.6	3.5	3.2	2.4
Fasting Glucose	1.4	1.7	2.6	1.1	1.3	1.1	1.4	1.6	-1.2	1.4	1.5	1.4	1.3	1.2	1.0	1.2	1.5	1.1
HbA1C	0.7	0.8	1.6	-1.2	1.1	0.5	1.1	0.7	-0.7	1.0	1.1	1.2	0.9	0.3	1.0	0.3	0.6	-0.0
HDL Cholesterol	5.4	9.1	12.9	-2.8	-2.9	-3.1	-3.0	-3.6	3.2	-3.0	-3.2	-2.9	-3.1	-2.5	-2.1	-2.8	-3.3	-3.6
LDL Cholesterol	0.8	1.2	3.4	1.0	1.0	1.2	1.1	1.8	-0.7	0.9	1.0	1.2	1.2	1.2	-0.6	1.2	1.0	0.9
Lupus	2.2	3.3	7.2	-1.4	-2.0	-1.9	-1.9	-1.6	1.4	-1.5	-1.5	-1.8	-1.5	-1.9	-2.7	-2.0	-2.0	-1.6
Neuroticism (2016)	0.7	1.0	3.1	0.6	0.6	1.4	0.4	1.6	-0.4	0.3	0.4	0.4	0.3	1.2	1.8	1.1	0.9	1.6
Primary Biliary Cirrhosis	0.2	0.2	0.9	0.3	0.4	0.0	0.6	-0.1	-0.3	0.6	0.9	0.6	0.5	-0.0	-0.7	0.2	0.3	0.5
Rheumatoid Arthritis	1.5	2.1	4.6	-1.4	-1.2	-1.4	-1.6	-2.1	1.3	-1.6	-1.4	-1.5	-1.7	-1.4	-1.0	-1.5	-1.3	-1.1
Schizophrenia (2014)	0.2	0.3	1.3	-0.0	0.2	0.5	0.5	0.6	-0.4	0.5	0.4	0.6	0.5	1.1	-0.5	0.8	0.9	0.5
Triglycerides	2.1	3.4	4.8	1.4	1.9	2.2	2.1	1.1	-1.8	1.9	2.1	2.1	2.1	1.8	0.0	1.9	2.1	1.9
Type 2 Diabetes (T2D) (2012)	0.3	0.4	1.6	1.3	0.3	0.0	0.4	0.4	-0.6	0.5	0.3	0.1	0.4	1.0	0.0	0.8	0.5	0.7
Ulcerative Colitis	0.2	0.3	1.4	1.2	-0.3	0.0	-0.0	-1.1	0.0	0.0	0.2	-0.2	-0.1	-0.7	-1.1	-0.3	-0.3	0.0
Blood Eosinophil Count	0.4	2.8	5.9	1.4	1.9	1.4	1.6	1.4	-1.3	1.6	1.5	1.4	1.6	2.4	1.8	2.2	2.2	0.8
Blood Platelet Count	0.0	0.1	0.3	0.2	0.1	-0.2	-0.1	-0.4	0.4	-0.1	-0.1	-0.1	-0.1	0.5	-0.1	0.4	-0.1	0.2
Blood Red Count	0.5	5.0	8.3	2.6	2.2	2.2	1.9	2.9	-2.2	1.9	1.9	1.9	2.0	2.2	2.3	2.2	2.1	2.8
Blood White Count	0.7	5.2	8.1	1.4	2.5	2.4	2.1	1.8	-2.4	2.0	2.0	2.1	2.3	2.8	2.8	2.6	2.5	2.1
Heel T-Score	0.0	0.4	1.3	-1.0	-0.3	-0.6	-0.3	-1.2	0.4	-0.2	-0.5	-0.4	-0.4	-0.3	-0.4	-0.3	-0.6	-1.1
BMI	8.3	48.3	53.7	6.8	7.3	6.8	7.0	6.4	-7.1	6.9	6.6	7.0	7.1	6.9	7.0	7.3	7.3	6.6
Height	0.2	3.0	4.2	0.4	1.9	1.5	1.8	0.1	-1.9	1.9	2.0	1.9	2.0	1.8	2.0	1.6	1.7	2.0
Waist Hip Ratio (WHR)	0.3	1.2	13.5	-1.0	-0.1	0.3	0.1	-3.7	-0.2	0.2	0.1	0.0	0.3	1.3	0.2	0.8	0.7	0.3
Systolic Blood Pressure	0.3	1.3	2.6	-1.3	-1.6	-0.1	-1.3	-1.0	0.6	-1.2	-1.2	-1.3	-1.2	-1.2	-1.4	-1.2	-0.6	-1.0
Smoking Status	7.2	17.3	22.7	3.6	4.2	4.6	4.3	2.7	-4.1	4.2	3.9	4.2	4.2	4.6	3.6	4.8	4.7	4.3
Allergy or Eczema	0.2	0.5	1.4	-0.5	-0.7	-0.8	-0.7	-0.0	0.2	-0.6	-0.7	-0.7	-0.6	-1.0	-0.5	-1.0	-0.9	-1.2
Cardiovascular Disease	0.2	0.7	1.9	-0.1	0.8	1.4	0.7	0.3	-1.0	0.7	0.4	0.6	0.6	0.7	1.2	0.9	1.3	0.2
Hypothyroidism (self reported)	0.1	0.2	1.2	0.4	0.0	-0.9	-0.3	1.1	0.4	-0.2	0.0	-0.2	-0.2	-0.5	-0.0	-0.3	-0.6	-0.2
Respiratory disease	0.2	0.4	1.4	1.0	0.0	0.3	0.4	-0.1	-0.6	0.5	0.3	0.3	0.5	1.0	1.2	0.7	0.9	-0.3
Type 2 Diabetes (T2D) (2018)	1.5	2.8	3.9	1.4	1.9	1.6	1.8	0.8	-1.6	1.8	1.8	1.8	1.7	1.9	1.1	2.0	1.6	2.0
Lung FEV1/FVC ratio	0.6	2.9	6.3	1.1	1.8	2.1	1.6	2.3	-1.6	1.6	1.2	1.6	1.4	1.2	1.5	1.8	1.7	2.5
Lung FVC	4.2	21.5	28.6	-2.8	-4.8	-4.7	-4.9	-3.0	5.3	-5.0	-4.8	-4.9	-5.0	-5.0	-4.1	-5.1	-5.3	-4.0
Neuroticism	0.2	0.5	6.2	-0.2	0.0	0.0	-0.2	2.5	0.3	-0.2	-0.2	-0.2	-0.1	0.6	0.1	0.3	0.1	0.8
Chronotype (morning person)	0.1	0.1	1.0	0.1	0.0	0.2	0.1	0.0	-0.3	0.1	0.1	0.1	-0.0	-1.0	0.4	-0.6	-0.6	0.2
Hair Pigment	0.0	0.7	4.0	0.2	0.7	0.1	0.3	-2.0	-0.9	0.5	0.6	0.4	0.6	0.7	1.0	0.3	0.6	-1.3
Tanning	0.1	1.3	4.5	-2.1	-0.7	-1.2	-0.8	-0.9	1.2	-0.8	-1.1	-1.0	-1.1	-1.4	0.2	-1.1	-1.2	-1.3
Hand grip strength (left)	2.5	6.6	12.2	-2.6	-2.1	-2.5	-2.5	-2.1	2.4	-2.5	-2.6	-2.4	-2.7	-3.5	-1.8	-3.0	-3.1	-2.1
Number of treatments/medications taken	0.6	1.0	1.6	-1.1	-1.2	-1.1	-1.2	-0.5	1.1	-1.1	-1.2	-1.3	-1.3	-0.9	0.0	-1.0	-0.9	0.5
Average weekly spirits intake	2.2	2.7	7.3	0.3	1.5	1.7	1.6	0.8	-1.1	1.6	1.5	1.4	1.6	2.7	1.4	2.4	2.3	1.4
Sensitivity / hurt feelings	0.3	0.5	1.1	-1.0	-0.7	-0.7	-0.6	0.1	0.8	-0.6	-0.7	-0.7	-0.8	-0.4	-1.0	-0.6	-0.9	-0.2
Frequency of depressed mood in last 2 weeks	0.2	0.2	2.6	0.1	-0.1	-0.6	-0.0	1.6	0.1	0.0	-0.1	-0.1	-0.0	0.2	0.1	0.2	-0.1	-0.3
Hearing difficulty/problems: Yes	1.6	2.5	5.0	0.6	1.8	1.7	1.4	1.6	-1.8	1.4	1.3	1.5	1.4	1.3	2.2	1.4	1.4	2.2
Relative age of first facial hair	1.5	3.1	5.6	-1.6	-1.8	-2.1	-1.8	-2.4	1.9	-1.7	-1.5	-1.7	-1.7	-1.3	-1.7	-1.6	-1.7	-1.9
Other serious medical condition/disability diagnosed by doctor	1.0	1.2	2.6	-1.6	-1.2	-0.7	-1.1	-0.9	1.4	-1.2	-1.3	-1.2	-1.3	-1.2	-0.9	-1.0	-0.6	-0.1
Ever used hormone-replacement therapy (HRT)	0.2	0.2	1.2	0.7	0.4	0.2	0.3	1.1	-0.3	0.3	0.4	0.3	0.3	-0.3	0.8	-0.1	0.2	0.4
Ever had hysterectomy (womb removed)	0.1	0.1	0.2	-0.1	-0.4	-0.3	-0.4	-0.1	0.0	-0.3	-0.3	-0.3	-0.5	-0.3	-0.0	-0.4	-0.5	-0.2
Systolic blood pressure, automated reading	0.1	0.3	1.0	0.4	0.3	0.8	0.5	0.5	-1.0	0.6	0.6	0.4	0.6	0.4	0.0	0.6	0.8	0.6
Eye problems/disorders: Diabetes related eye disease	0.1	0.2	0.8	-0.4	0.3	0.2	0.0	-0.9	-0.8	0.2	0.0	0.2	0.2	0.6	0.0	0.3	0.3	0.3
Angina	0.4	0.5	1.7	-0.4	-0.8	-1.0	-0.7	0.5	0.8	-0.5	-0.8	-0.7	-0.6	-0.2	-0.3	-0.4	-0.4	-1.3
Medication for hormone replacement therapy	0.0	0.0	0.3	-0.0	0.0	0.1	0.0	-0.2	0.1	0.0	0.1	-0.0	-0.1	0.2	0.6	0.2	-0.3	-0.1
Vitamin and mineral supplements	2.3	3.1	6.2	-0.4	-2.1	-1.6	-1.9	-1.0	1.4	-1.8	-1.8	-1.8	-1.8	-2.0	-1.8	-2.0	-1.9	-2.5
Supplements: Zinc	1.6	1.8	2.5	1.4	1.2	1.5	1.1	1.5	-1.6	1.2	1.1	1.3	1.3	1.5	1.4	1.2	1.5	1.0
Medication: Co-codamol	0.3	0.4	1.3	-0.4	0.4	0.6	0.7	-0.2	-0.2	0.5	0.3	0.6	0.7	1.1	0.3	0.9	0.8	0.7
Medication: Metformin	0.1	0.2	0.6	-0.3	-0.3	-0.8	-0.3	-0.4	0.8	-0.3	-0.3	-0.4	-0.3	0.2	-0.3	0.1	-0.5	-0.3
Diabetes (father)	0.9	1.1	2.2	1.5	0.6	1.1	1.0	1.0	-1.2	1.1	1.0	1.0	1.1	1.2	0.7	1.0	1.1	0.2
Diabetes (mother)	0.8	1.0	2.3	-0.2	1.1	1.1	0.9	0.6	-1.0	0.9	0.8	0.8	0.9	1.5	0.5	1.4	1.2	1.1
Severe depression (siblings)	0.8	0.9	2.3	-1.2	-0.3	-1.5	-0.6	-1.1	1.4	-0.7	-0.8	-0.6	-0.8	-1.4	-0.9	-1.0	-1.0	-0.3
Pack years adult smoking proportion	0.5	0.8	1.7	0.6	0.8	0.9	0.8	1.1	-0.6	0.8	0.7	0.7	0.9	1.3	1.0	1.0	1.3	-0.1
Impedance of leg (right)	1.7	8.1	11.8	-2.9	-2.9	-3.0	-2.9	-3.4	3.0	-2.8	-2.7	-2.9	-2.9	-3.0	-2.4	-3.0	-2.8	-1.6
Leg fat-free mass (left)	4.4	23.3	27.7	4.6	5.1	4.8	4.9	4.1	-5.3	4.9	4.8	4.9	5.0	4.6	4.7	4.9	5.0	4.7
Trunk fat percentage	6.6	26.4	30.9	4.8	5.4	4.7	5.3	3.8	-5.5	5.4	5.2	5.3	5.4	5.1	4.8	5.3	5.3	5.6
Hand grip strength (right)	1.5	4.0	10.1	-1.5	-1.5	-2.2	-1.9	-1.6	1.4	-1.8	-2.0	-1.8	-1.9	-3.2	-0.9	-2.7	-2.7	-1.7
Townsend deprivation index at recruitment	3.5	4.9	9.9	1.5	2.3	2.3	2.2	1.8	-2.0	2.1	1.9	2.1	2.2	3.1	1.8	2.7	3.0	1.3
Current tobacco smoking	1.3	2.1	3.9	1.3	1.4	2.0	1.5	0.3	-1.2	1.3	1.2	1.3	1.5	1.6	1.5	1.6	1.9	1.1
Average weekly fortified wine intake	0.5	0.5	2.0	-0.5	-0.5	-0.6	-0.7	0.3	0.7	-0.7	-0.8	-0.7	-0.7	-1.4	0.6	-1.0	-0.9	0.1
Maternal smoking around birth	0.7	1.0	2.9	-0.5	-0.8	-1.3	-0.8	-1.2	1.2	-0.8	-1.0	-0.8	-1.0	-0.8	-1.1	-0.8	-1.1	-1.7
Fed-up feelings	0.8	1.4	4.4	1.4	1.1	0.8	1.1	2.1	-1.0	1.2	1.0	1.0	1.1	0.9	0.7	1.0	1.1	1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.7	4.4	0.7	1.2	1.1	1.2	1.4	-1.2	1.2	1.1	1.1	1.2	2.1	1.2	1.7	1.5	1.3
Relative age voice broke	2.0	3.1	6.0	-0.9	-1.7	-2.4	-1.7	-1.5	2.4	-1.7	-1.6	-1.7	-1.8	-1.3	-1.9	-1.4	-2.0	-1.9
Taking other prescription medications	0.5	0.8	2.2	-1.5	-1.2	-0.8	-1.0	-0.3	1.0	-1.0	-0.8	-1.0	-1.0	-0.5	-0.9	-0.7	-0.6	-0.2
Age when periods started (menarche)	2.0	4.9	8.5	-2.9	-2.2	-2.4	-2.4	-1.3	2.7	-2.3	-2.2	-2.2	-2.4	-2.0	-2.0	-2.2	-2.4	-0.7
Bilateral oophorectomy (both ovaries removed)	5.2	6.0	9.2	-1.6	-2.5	-3.0	-2.7	-1.4	2.5	-2.5	-2.7	-2.6	-2.7	-2.5	-1.7	-2.6	-2.9	-2.2
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.1	0.4	-0.2	0.2	0.3	0.2	0.6	-0.5	0.2	0.0	0.2	0.2	0.0	0.4	0.1	-0.2	-0.2
Tinnitus: Yes, but not now, but have in the past	0.2	0.3	0.8	0.1	0.4	0.5	0.4	0.4	-0.9	0.6	0.3	0.4	0.6	0.5	0.8	0.3	0.6	0.3
Qualifications: CSEs or equivalent	0.1	0.2	1.0	0.9	-0.1	0.6	-0.0	1.0	-0.3	-0.1	-0.2	0.1	-0.0	0.0	-0.3	-0.2	0.5	-0.1
Serious illness, injury or assault to yourself	0.7	0.8	1.6	-0.6	-1.3	-0.5	-1.1	-0.7	1.1	-1.1	-1.1	-1.2	-1.2	-0.5	-0.4	-0.8	-0.6	-0.4
High blood pressure	0.0	0.1	0.7	-0.4	0.0	0.2	-0.0	-0.8	-0.3	0.0	-0.1	-0.1	-0.1	-0.1	0.4	0.2	0.1	-0.4
Hayfever, allergic rhinitis or eczema	0.1	0.3	1.0	0.0	-0.3	-0.7	-0.5	0.1	0.0	-0.4	-0.6	-0.5	-0.4	-0.7	-0.1	-0.8	-0.7	-1.0
Multivitamins +/- minerals	5.2	6.7	10.0	1.1	2.8	2.6	2.7	1.0	-2.5	2.8	2.6	2.6	2.8	2.9	2.2	2.9	2.9	3.2
Stomach or abdominal pain in last month	0.3	0.4	1.1	-0.3	0.9	0.6	0.7	1.0	-0.5	0.5	0.3	0.7	0.5	0.2	1.0	0.5	0.2	1.0
Supplements: Glucosamine	0.5	0.7	1.6	0.6	0.6	0.7	0.8	1.2	-0.9	0.8	0.7	0.8	0.9	0.6	0.6	0.5	0.6	1.3
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	2.4	1.6	0.4	0.2	0.4	0.1	-0.6	0.6	0.4	0.5	0.6	0.6	0.6	0.3	0.5	0.6
Medication: Atenolol	0.2	0.2	0.8	-0.9	0.2	0.8	0.1	0.3	-0.3	0.0	0.0	0.1	-0.0	0.4	0.5	0.5	0.5	0.5
Medication: Levothyroxine sodium	0.1	0.3	2.3	0.4	0.4	0.1	0.3	1.5	-0.1	0.3	0.5	0.2	0.3	0.0	0.3	0.3	0.1	0.6
Sitting height	0.1	0.8	2.2	0.3	1.1	0.7	0.8	0.4	-1.1	0.9	0.9	0.8	0.9	0.3	1.5	0.4	1.1	1.3
Chronic bronchitis/emphysema (father)	2.1	2.4	5.0	1.6	1.5	1.7	1.6	0.8	-1.3	1.6	1.7	1.5	1.4	1.2	1.8	1.6	1.5	2.2
High blood pressure (mother)	0.6	0.8	1.8	-0.4	-1.3	-0.2	-1.1	-0.3	0.7	-1.1	-1.2	-1.1	-1.1	-1.0	-1.0	-1.1	-0.7	-0.5
Body mass index (BMI)	8.5	36.1	41.1	6.0	6.4	5.6	6.2	5.4	-6.3	6.2	5.9	6.2	6.2	6.1	5.6	6.4	6.2	5.5
Impedance of leg (left)	1.8	8.6	12.6	-3.0	-3.0	-3.0	-3.0	-3.6	3.1	-2.9	-2.8	-2.9	-2.9	-3.1	-2.3	-3.2	-3.0	-1.7
Leg predicted mass (left)	4.3	22.6	27.2	4.5	5.0	4.7	4.8	4.0	-5.2	4.9	4.8	4.8	5.0	4.5	4.6	4.8	4.9	4.6
Trunk fat mass	8.0	34.2	38.8	5.4	6.2	5.4	6.0	4.4	-6.2	6.0	5.9	6.0	6.1	5.8	5.7	6.1	6.1	6.1
Waist circumference	9.7	35.5	42.0	5.4	6.3	5.6	6.2	4.0	-6.2	6.2	5.9	6.1	6.3	6.3	5.6	6.5	6.4	5.9
Number of incorrect matches in round	3.4	5.6	6.8	-2.1	-2.6	-2.4	-2.6	-1.2	2.4	-2.4	-2.5	-2.6	-2.6	-2.0	-2.6	-2.4	-2.2	-2.5
Past tobacco smoking	6.3	11.6	16.3	-2.5	-3.5	-3.4	-3.5	-2.9	3.4	-3.5	-3.4	-3.5	-3.4	-3.6	-2.9	-3.8	-3.5	-4.0
Alcohol usually taken with meals	0.9	1.4	2.8	-1.6	-1.0	-1.4	-1.4	0.1	0.8	-1.3	-1.1	-1.2	-1.1	-1.1	-0.6	-1.4	-1.7	-0.9
Nervous feelings	2.5	4.7	6.7	-1.1	-2.2	-2.1	-2.4	-0.2	2.6	-2.5	-2.6	-2.4	-2.6	-2.3	-2.2	-2.2	-2.3	-1.5
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	3.1	0.5	0.6	0.2	0.4	1.8	-0.4	0.5	0.2	0.5	0.5	1.4	0.9	1.0	1.0	0.5
Hearing difficulty/problems with background noise	0.2	0.3	1.8	-0.7	0.4	0.2	-0.1	0.7	-0.4	-0.0	-0.1	-0.0	-0.0	0.5	0.7	0.4	0.3	1.3
Hair/balding pattern: Pattern 2	0.4	0.6	2.8	0.5	0.7	0.3	0.4	-0.4	-0.5	0.5	0.6	0.5	0.5	1.1	1.7	0.8	0.8	0.7
Had menopause	0.2	0.2	1.0	-1.0	-0.2	-0.4	-0.2	-0.1	0.6	-0.3	-0.1	-0.3	-0.3	-0.8	0.2	-0.5	-0.4	0.3
Had other major operations	0.8	1.0	2.0	-0.1	-1.2	-0.5	-1.2	-0.1	1.1	-1.3	-1.4	-1.2	-1.4	-0.8	-1.1	-0.7	-0.9	0.1
Forced vital capacity (FVC)	1.6	6.1	8.6	-1.0	-2.7	-2.5	-2.7	-1.8	2.4	-2.6	-2.5	-2.6	-2.7	-2.9	-2.5	-2.9	-2.9	-1.6
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.6	1.4	0.6	0.9	0.7	0.8	0.2	-1.1	0.8	0.6	0.8	0.8	0.9	1.2	0.8	0.6	0.2
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.2	-0.4	-0.3	-0.1	-0.3	-0.0	0.4	-0.2	-0.4	-0.4	-0.3	0.1	0.4	-0.1	0.3	-0.0
Qualifications: None of the above	1.9	4.0	7.1	2.6	1.9	1.3	2.0	1.3	-1.9	2.1	2.1	1.9	2.0	2.2	2.7	2.1	2.0	1.2
Financial difficulties in last 2 years	6.1	8.1	13.8	2.0	3.0	2.7	3.0	1.8	-2.5	2.9	2.9	3.0	3.0	3.7	2.6	3.5	3.4	1.8
Mouth/teeth dental problems	1.4	2.2	3.5	-1.0	-1.5	-1.2	-1.6	-1.0	1.4	-1.6	-1.6	-1.5	-1.5	-1.4	-1.9	-1.5	-1.5	-1.8
Heart attack	1.2	1.5	2.9	-0.9	-1.3	-0.6	-1.6	-1.0	1.4	-1.6	-1.6	-1.6	-1.7	-1.1	-0.6	-1.1	-0.9	-0.4
Allergy	0.1	0.2	1.2	-0.5	0.3	0.3	0.4	-0.6	0.3	0.2	0.4	0.3	0.2	-0.0	-0.5	0.3	0.0	1.1
Pain all over the body in last month	1.4	1.5	2.2	0.3	1.1	1.0	1.4	-0.0	-1.2	1.5	1.4	1.4	1.5	1.5	1.0	1.5	1.4	1.0
Diabetes (self-reported)	0.7	1.0	1.9	0.7	1.2	1.2	1.2	0.2	-0.8	1.1	1.0	1.1	0.9	1.1	0.4	1.4	0.9	1.2
Hayfever/allergic rhinitis (self-reported)	1.4	1.9	5.2	2.3	1.3	1.2	1.4	1.7	-1.3	1.4	1.2	1.4	1.4	1.0	1.3	1.1	1.0	0.8
Medication: Ramipril	0.0	0.1	0.2	0.1	0.1	0.1	0.1	0.3	-0.5	0.2	0.1	0.1	0.2	-0.0	0.4	0.2	0.2	0.3
Medication: Simvastatin	0.8	1.1	3.4	-0.4	-0.8	-0.5	-1.2	-1.9	0.6	-1.2	-1.1	-1.1	-1.2	-1.5	-0.1	-1.2	-1.1	-0.3
Fluid intelligence score	0.1	0.1	0.4	-0.6	0.0	0.3	0.0	-0.4	0.2	-0.1	-0.1	0.1	0.0	0.6	-0.3	0.4	0.2	0.7
Illnesses of siblings	0.6	0.8	1.1	1.1	1.0	0.9	1.0	0.8	-0.9	1.0	0.9	0.9	0.9	0.7	0.7	0.9	1.0	0.5
Neuroticism score	0.2	0.4	2.4	-0.1	-0.5	-0.5	-0.6	1.6	0.6	-0.6	-0.7	-0.6	-0.5	-0.2	-0.2	-0.4	-0.4	0.3
Weight	7.8	38.4	43.3	5.9	6.5	5.8	6.3	5.2	-6.6	6.4	6.2	6.3	6.5	6.1	5.9	6.4	6.5	6.2
Impedance of arm (right)	1.4	6.6	10.4	-3.2	-2.8	-2.3	-2.6	-3.1	2.3	-2.5	-2.2	-2.6	-2.5	-2.5	-2.4	-2.8	-2.5	-1.8
Arm fat percentage (right)	8.1	31.8	36.3	5.0	6.0	5.2	5.9	4.7	-6.0	5.9	5.7	5.8	5.9	5.9	5.1	6.0	6.0	5.4
Trunk fat-free mass	2.9	16.9	19.5	3.8	4.4	4.1	4.1	3.2	-4.4	4.1	4.1	4.1	4.2	4.0	4.2	4.2	4.3	4.1
Hip circumference	8.2	35.2	38.8	6.1	6.2	5.4	6.0	5.9	-6.2	6.1	5.9	6.0	6.0	5.6	5.6	6.0	6.1	5.7
Time employed in main current job	2.8	3.3	6.3	-1.6	-1.7	-2.3	-1.8	-0.2	1.8	-1.7	-1.9	-1.7	-1.7	-2.1	-1.5	-2.1	-2.5	-1.4
Alcohol intake versus 10 years previously	4.7	7.0	8.4	2.2	2.6	2.8	2.8	2.1	-2.6	2.8	2.9	2.8	2.8	2.8	1.8	2.8	2.9	2.6
Father’s age at death	0.2	0.2	1.8	-0.6	0.3	-0.2	0.2	1.3	-0.1	0.3	0.9	0.3	0.3	-0.2	0.1	-0.1	-0.1	-0.3
Worrier / anxious feelings	6.2	11.8	15.8	-3.0	-3.5	-3.2	-3.8	-1.2	3.5	-3.9	-4.0	-3.8	-3.8	-3.6	-3.3	-3.6	-3.8	-2.4
Frequency of tiredness / lethargy in last 2 weeks	2.0	3.2	5.6	1.7	1.7	1.6	1.5	2.4	-1.8	1.5	1.3	1.6	1.6	2.1	1.8	1.8	1.9	2.2
Falls in the last year	0.2	0.3	1.7	-0.6	-0.3	-0.5	-0.2	0.3	0.8	-0.3	-0.3	-0.3	-0.3	-0.0	-0.8	-0.1	-0.2	-1.3
Hair/balding pattern: Pattern 3	0.1	0.1	0.6	0.3	0.1	0.5	0.2	0.5	-0.5	0.3	0.2	0.1	0.2	-0.2	-0.8	-0.0	0.1	0.3
Number of live births	16.9	23.9	28.5	3.5	5.3	4.6	5.1	4.4	-4.9	5.1	5.1	5.2	5.1	4.8	5.2	5.1	5.0	4.6
Forced expiratory volume in 1-second (FEV1)	1.0	3.5	7.0	-0.5	-1.9	-1.8	-2.0	-0.8	1.7	-2.0	-1.9	-1.9	-2.1	-2.6	-1.7	-2.4	-2.4	-0.6
Pulse rate	1.8	3.1	5.6	1.7	1.6	1.8	1.5	2.4	-1.5	1.6	1.6	1.4	1.6	1.6	2.4	1.6	1.8	1.9
Happiness	0.2	0.2	0.7	-0.5	-0.5	-0.2	-0.5	-0.5	0.6	-0.5	-0.8	-0.5	-0.5	-0.4	-0.5	-0.3	0.1	-0.6
Noisy workplace	0.5	0.6	4.0	1.4	0.7	0.3	0.7	2.0	-0.1	0.7	0.5	0.5	0.6	-0.1	0.6	0.3	0.5	0.5
Qualifications: A levels/AS levels or equivalent	4.4	9.7	12.0	-3.3	-3.1	-2.6	-3.2	-3.5	3.0	-3.1	-3.3	-3.1	-3.2	-3.5	-2.1	-3.4	-3.2	-2.9
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.7	-0.9	0.1	-0.5	0.3	-0.3	0.2	0.3	0.2	0.1	0.2	0.8	0.4	0.7	-0.2	0.8
Mouth/teeth dental problems: Dentures	0.1	0.2	1.1	0.0	-0.2	-0.2	-0.4	-1.0	0.4	-0.5	-0.5	-0.4	-0.4	0.1	0.8	0.1	-0.1	0.5
Asthma	0.2	0.3	1.2	0.8	0.1	0.4	0.4	0.6	-0.5	0.4	0.1	0.3	0.4	1.0	1.1	0.7	0.6	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	2.6	-1.6	-0.4	-0.7	-0.4	-0.2	0.9	-0.5	-0.7	-0.5	-0.6	-0.9	-0.6	-0.7	-0.9	-0.3
Medication: Cholesterol lowering	1.7	2.6	3.6	-1.5	-1.6	-1.7	-1.8	-1.8	1.9	-1.8	-1.9	-1.8	-1.8	-1.2	-0.3	-1.5	-1.6	-1.4
Depression (self-reported)	0.4	0.5	1.1	-1.0	-0.4	-0.8	-0.7	0.6	0.6	-0.7	-0.8	-0.6	-0.6	-1.0	-0.0	-1.0	-0.6	0.3
Medication: Lansoprazole	0.6	0.7	2.0	-0.4	-0.9	-1.4	-0.7	-0.4	1.0	-0.5	-0.6	-0.7	-0.7	-0.7	-0.5	-0.8	-1.1	-1.3
Prospective memory result	1.4	1.8	2.6	0.6	1.3	1.2	1.5	1.6	-1.6	1.4	1.2	1.4	1.4	1.6	1.1	1.6	1.1	0.9
Lung cancer (father)	3.1	3.7	6.2	1.5	1.9	1.5	2.1	2.5	-1.7	2.2	2.1	2.1	2.1	2.0	1.5	2.0	2.0	1.1
Illnesses of mother	0.5	0.6	1.1	0.8	0.7	0.9	0.7	0.1	-1.1	0.8	0.7	0.8	0.9	1.0	0.5	1.0	0.7	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	1.3	4.1	6.3	-1.3	-2.2	-1.9	-2.2	-1.4	1.9	-2.2	-2.1	-2.1	-2.2	-2.5	-1.9	-2.4	-2.4	-0.9
Pulse wave Arterial Stiffness index	1.0	1.1	1.6	1.0	0.4	1.3	1.2	0.2	-1.2	1.3	1.1	1.2	1.2	1.1	-0.8	1.1	1.3	0.6
Impedance of arm (left)	2.0	9.3	12.0	-3.1	-3.4	-2.9	-3.2	-3.1	2.9	-3.0	-2.8	-3.1	-3.1	-3.1	-3.0	-3.5	-3.2	-2.1
Arm fat mass (right)	8.9	36.6	41.8	5.7	6.5	5.6	6.3	5.0	-6.4	6.3	6.1	6.2	6.4	6.1	5.7	6.4	6.4	5.7
Trunk predicted mass	2.9	16.6	19.2	3.7	4.4	4.0	4.1	3.2	-4.4	4.1	4.0	4.1	4.2	4.0	4.2	4.2	4.3	4.0
Standing height	0.1	1.2	4.4	0.4	0.9	1.1	0.9	-0.1	-1.4	1.1	1.2	1.0	1.1	0.6	1.3	0.6	1.1	2.1
Length of working week for main job	2.9	3.2	4.6	-1.8	-1.8	-1.5	-2.0	-1.6	1.4	-2.0	-2.1	-1.9	-1.9	-2.0	-1.2	-2.0	-2.1	-0.8
Exposure to tobacco smoke at home	1.9	2.1	3.5	1.9	1.4	1.3	1.4	1.6	-1.3	1.3	1.2	1.3	1.3	1.9	1.5	1.7	1.7	0.9
Breastfed as a baby	3.0	3.7	6.0	0.8	2.4	1.8	2.0	1.8	-2.1	2.0	2.1	2.0	2.1	1.3	2.2	1.8	1.5	2.4
Tense / ‘highly strung’	2.3	3.8	5.6	-1.7	-2.1	-1.9	-2.3	-0.4	2.3	-2.3	-2.4	-2.2	-2.3	-1.4	-1.5	-1.6	-1.8	-2.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	4.1	1.1	0.8	0.1	0.5	1.7	-0.2	0.6	0.5	0.5	0.6	1.1	2.0	0.7	0.8	0.9
Hair/balding pattern: Pattern 4	0.2	0.6	4.8	0.3	-0.4	-0.6	-0.3	2.2	0.6	-0.4	-0.6	-0.3	-0.5	-0.2	-0.3	-0.3	-0.4	-1.3
Birth weight of first child	0.7	1.2	5.4	0.1	0.9	1.2	0.9	0.8	-1.5	0.9	1.0	0.9	1.0	0.7	1.3	0.8	0.7	2.3
Peak expiratory flow (PEF)	0.2	0.4	1.9	-0.0	-0.5	-0.4	-0.6	0.2	0.2	-0.4	-0.4	-0.6	-0.6	-1.4	-0.7	-1.0	-0.9	0.5
Pulse wave reflection index	0.2	0.2	1.0	-0.3	-0.2	0.4	0.3	-0.8	-0.3	0.3	0.2	0.4	0.2	0.5	-1.0	0.5	0.3	0.2
Ever highly irritable/argumentative for 2 days	1.5	1.8	6.2	0.6	1.5	1.2	1.3	1.3	-1.2	1.3	1.0	1.3	1.3	1.4	2.5	1.2	1.4	0.4
Loud music exposure frequency	1.3	1.4	2.2	0.4	1.4	1.5	1.0	0.8	-1.2	1.0	1.1	1.1	1.0	1.3	1.3	1.3	1.4	1.3
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	2.8	-1.7	-1.0	-0.7	-0.9	-0.6	0.9	-0.8	-0.8	-0.9	-0.9	-0.9	-1.1	-1.0	-1.1	-0.8
Mouth/teeth dental problems: Bleeding gums	4.3	5.6	7.8	0.7	2.4	2.5	2.7	1.2	-2.6	2.7	2.8	2.5	2.5	2.4	1.6	2.6	2.3	2.8
Blood clot in the leg (DVT)	0.2	0.2	0.7	-0.7	0.1	0.6	0.2	-0.6	-0.8	0.4	0.4	0.3	0.3	0.0	0.4	0.0	0.5	0.6
Medication: Paracetamol	0.1	0.2	1.7	0.3	-0.1	-0.5	-0.1	1.3	0.5	-0.0	-0.4	-0.1	-0.2	-0.0	0.7	-0.2	-0.5	0.4
Headache pain in last month	0.2	0.3	3.0	0.4	0.3	-0.7	0.1	1.7	0.1	0.1	0.1	0.2	0.1	-0.4	0.8	-0.2	-0.5	-0.4
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	1.4	0.8	0.9	0.7	1.1	0.8	-1.1	1.1	1.2	1.1	1.1	0.7	-0.1	0.8	0.8	0.6
Glaucoma (self-reported)	0.9	1.1	4.1	-1.5	-0.9	-0.6	-1.0	-0.8	0.6	-0.9	-1.0	-1.1	-1.0	-1.0	-0.5	-1.0	-1.0	-2.0
Gout (self-reported)	0.3	0.5	1.5	-0.1	-0.5	-1.0	-0.6	-1.2	0.8	-0.5	-0.5	-0.5	-0.6	-0.5	-0.0	-0.8	-0.9	-0.7
Hypothyroidism/myxoedema (self-reported)	0.2	0.3	1.0	-0.1	-0.3	-1.0	-0.4	0.5	0.7	-0.4	-0.2	-0.5	-0.4	-0.8	-0.5	-0.5	-0.9	-0.3
Medication: Amlodipine	0.0	0.1	0.3	0.2	-0.0	0.5	-0.1	-0.2	0.1	-0.1	-0.2	-0.2	-0.2	0.2	0.5	0.2	0.3	0.4
Medication: Ventolin 100micrograms inhaler	0.7	0.9	2.9	1.4	0.5	1.1	0.7	0.6	-0.6	0.7	0.6	0.7	0.7	1.7	0.9	1.4	1.2	0.2
Birth weight	0.1	0.2	1.3	-0.2	0.4	0.3	0.4	1.1	-0.5	0.3	0.4	0.5	0.5	-0.0	0.1	0.1	0.2	0.9
Chronic bronchitis/emphysema (mother)	0.1	0.2	0.4	0.5	0.5	0.0	0.4	0.4	-0.2	0.6	0.3	0.5	0.4	0.7	-0.1	0.3	0.2	0.4
High blood pressure (siblings)	0.3	0.4	2.0	-1.4	-0.5	-0.7	-0.5	-0.4	0.7	-0.5	-0.5	-0.4	-0.5	-0.8	-0.5	-0.7	-0.8	-0.1
Forced vital capacity (FVC), Best measure	1.8	6.7	9.3	-1.4	-2.9	-2.4	-2.8	-2.3	2.6	-2.8	-2.7	-2.7	-2.8	-3.0	-2.3	-3.0	-2.9	-1.5
Body fat percentage	8.1	32.1	36.2	5.2	6.0	5.1	5.9	4.4	-6.0	5.9	5.7	5.8	6.0	5.7	5.3	6.0	5.9	5.9
Leg fat percentage (right)	10.1	36.6	43.2	5.4	6.6	5.3	6.3	4.9	-6.2	6.3	6.1	6.2	6.4	6.2	5.9	6.6	6.3	5.9
Arm fat-free mass (right)	3.7	18.8	22.1	4.3	4.7	4.1	4.4	3.8	-4.5	4.4	4.2	4.4	4.5	3.8	4.5	4.3	4.4	4.5
Exposure to tobacco smoke outside home	5.4	7.2	9.0	2.9	2.6	2.2	2.7	2.8	-2.7	2.7	2.6	2.7	2.7	3.0	2.8	2.8	2.5	2.2
Comparative body size at age 10	0.2	0.7	2.4	-1.6	-0.9	-0.2	-0.7	-0.8	1.0	-0.9	-0.8	-0.7	-0.8	-0.1	-1.1	-0.3	-0.6	-0.1
Number of full brothers	2.3	2.8	4.7	0.6	2.1	1.6	2.1	0.8	-1.7	2.0	1.9	2.2	2.0	1.6	1.5	1.8	1.6	1.0
Worry too long after embarrassment	2.2	3.7	5.2	-1.2	-2.1	-1.9	-2.3	0.1	1.7	-2.2	-2.3	-2.1	-2.1	-2.1	-2.0	-2.2	-2.2	-0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.8	-0.2	-0.5	-0.3	-0.6	-0.2	0.6	-0.7	-0.9	-0.7	-0.6	0.1	0.2	-0.2	-0.1	0.8
Wheeze or whistling in the chest in last year	4.7	8.3	12.2	2.5	2.7	2.7	2.7	3.3	-2.8	2.7	2.5	2.6	2.8	3.5	3.3	3.3	3.3	2.2
Number of children fathered	0.8	0.9	2.2	1.4	0.7	0.3	1.0	1.5	-0.6	0.8	0.8	0.8	0.9	1.0	0.8	1.1	1.0	0.6
Reason for reducing amount of alcohol drunk: Health precaution	7.5	8.7	13.8	-3.3	-2.7	-3.4	-2.8	-1.9	3.1	-2.8	-2.9	-2.9	-2.9	-3.1	-2.1	-3.0	-3.3	-3.7
Age at first live birth	11.7	20.7	28.2	-3.7	-4.8	-4.3	-4.8	-3.5	4.7	-4.9	-4.6	-4.7	-4.8	-5.3	-4.2	-5.0	-4.9	-3.7
Pulse wave peak to peak time	0.8	0.9	1.3	-0.9	-0.3	-1.1	-1.1	-0.2	1.1	-1.1	-1.0	-1.1	-1.0	-1.0	1.0	-1.0	-1.1	-0.4
Health satisfaction	0.7	0.9	2.5	1.6	0.8	0.7	0.8	0.5	-0.7	0.9	0.8	0.7	0.7	1.3	1.3	1.2	1.2	0.3
Shortness of breath walking on level ground	1.0	1.2	5.3	2.3	0.9	0.6	0.6	1.5	-0.3	0.7	0.6	0.7	0.6	1.3	1.5	1.0	0.9	1.0
Qualifications: College or University degree	2.5	7.8	11.8	-3.0	-2.4	-2.8	-2.7	-2.3	3.0	-2.8	-2.8	-2.7	-2.9	-3.4	-1.9	-3.0	-3.3	-2.6
Eye problems/disorders: None of the above	2.9	3.3	6.0	2.5	1.8	1.2	2.0	1.8	-1.8	2.0	2.2	2.1	2.1	1.6	1.0	1.6	1.6	1.5
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.4	0.9	0.7	0.7	0.8	0.7	-0.9	0.8	0.7	0.8	0.8	0.6	0.1	0.7	1.0	1.2
Emphysema/chronic bronchitis	0.3	0.3	2.3	1.5	0.1	0.1	-0.0	1.2	-0.3	0.1	-0.0	0.1	0.2	0.4	-0.4	0.2	0.6	-0.0
Medication for pain relief, constipation, heartburn	0.2	0.4	1.0	1.0	0.6	0.6	0.5	-0.8	-0.8	0.5	0.8	0.5	0.7	0.5	0.3	0.5	0.7	0.2
Neck or shoulder pain in last month	0.4	0.5	1.1	0.0	0.6	1.1	0.7	0.9	-0.8	0.7	0.4	0.7	0.7	1.0	0.1	0.9	1.0	0.4
Medication: Blood pressure	0.5	0.9	1.5	-0.1	-1.0	-0.7	-1.1	-0.9	1.0	-1.1	-1.2	-1.1	-1.2	-1.1	-0.4	-1.0	-0.9	-0.6
Angina (self-reported)	0.4	0.5	2.0	-0.2	-0.8	-1.1	-0.7	0.5	0.7	-0.5	-0.8	-0.7	-0.6	-0.3	-0.1	-0.5	-0.5	-1.4
Migraine (self-reported)	0.0	0.0	0.2	-0.1	-0.1	-0.1	0.0	-0.2	-0.2	-0.0	0.3	0.0	0.2	-0.4	-0.2	-0.3	0.0	-0.0
Medication: Ibuprofen	0.9	1.1	3.2	-1.8	-0.8	-1.1	-0.8	-0.7	1.3	-0.8	-1.0	-0.9	-1.0	-1.1	-1.0	-1.0	-1.3	-0.6
Medication: Allopurinol	0.1	0.2	0.4	0.4	0.4	-0.0	0.4	-0.2	-0.3	0.5	0.5	0.5	0.4	0.6	0.6	0.5	0.3	0.2
Medication: Omeprazole	0.2	0.2	1.6	0.2	-0.5	-0.2	-0.3	0.4	0.3	-0.2	-0.4	-0.2	-0.3	-0.3	-1.3	-0.3	0.0	-0.4
Medication: Seretide 50 evohaler	0.2	0.2	0.6	0.6	-0.1	0.7	0.1	0.1	-0.3	-0.0	-0.2	0.0	0.1	0.8	-0.5	0.6	0.7	0.4
Mean time to correctly identify matches	0.0	0.1	0.6	0.8	-0.0	-0.3	-0.0	-0.2	0.1	0.1	0.1	0.0	0.1	0.2	-0.3	0.0	0.3	-0.1
Heart disease (mother)	1.5	1.8	4.6	-2.1	-1.2	-1.6	-1.1	-0.8	1.5	-1.1	-1.2	-1.2	-1.2	-1.3	-0.0	-1.3	-1.4	-1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.6	2.0	9.4	-1.0	-1.2	-1.1	-1.1	-0.7	1.4	-1.2	-1.0	-1.1	-1.2	-1.0	-3.1	-1.0	-1.1	-2.0
Whole body fat mass	9.6	40.2	45.6	5.8	6.8	5.8	6.6	5.1	-6.6	6.6	6.4	6.5	6.6	6.3	6.0	6.7	6.6	6.4
Leg fat mass (right)	11.0	42.6	49.2	6.1	7.0	6.0	6.7	5.4	-6.7	6.7	6.5	6.7	6.8	6.5	6.4	6.9	6.9	6.4
Arm predicted mass (right)	3.6	18.7	22.0	4.2	4.7	4.1	4.4	3.7	-4.6	4.4	4.3	4.4	4.5	3.9	4.5	4.3	4.3	4.5
Pulse rate, automated reading	1.5	5.0	10.6	2.2	2.5	2.3	2.1	1.8	-2.0	2.1	2.0	2.0	2.2	1.7	3.2	2.0	2.4	2.5
Alcohol intake frequency.	1.7	3.9	6.4	2.1	1.9	1.8	1.8	1.6	-1.9	1.9	1.9	2.0	2.1	2.5	1.7	2.2	2.3	1.8
Comparative height size at age 10	0.7	3.7	6.9	2.2	1.4	2.6	1.7	1.0	-2.2	1.7	1.7	1.5	1.8	1.9	1.8	1.9	2.5	2.1
Number of full sisters	1.7	2.0	3.5	1.4	1.7	1.3	1.4	1.0	-1.2	1.4	1.5	1.4	1.3	1.9	1.2	1.7	1.7	1.0
Suffer from ‘nerves’	1.4	2.3	3.7	-1.1	-1.7	-1.3	-1.7	1.1	1.9	-1.7	-1.9	-1.8	-1.9	-0.9	-1.4	-1.2	-1.3	-1.1
Overall health rating	2.4	5.1	9.7	1.9	2.3	2.2	2.2	1.9	-2.2	2.2	2.0	2.2	2.1	2.2	2.3	2.3	2.3	3.1
Chest pain or discomfort	0.8	1.1	4.9	1.3	0.6	0.8	0.7	2.2	-0.6	0.6	0.3	0.5	0.6	0.9	0.7	0.9	0.9	2.2
Had major operations	0.0	0.1	0.2	-0.4	-0.1	0.1	-0.2	-0.3	0.1	-0.2	-0.1	-0.3	-0.3	0.1	-0.5	0.0	0.0	-0.1
Age at last live birth	3.1	4.5	7.7	-1.6	-2.2	-1.5	-2.1	-2.3	2.4	-2.4	-2.2	-2.3	-2.3	-2.8	-1.5	-2.4	-2.0	-1.4
Family relationship satisfaction	0.3	0.4	1.5	-1.2	-0.4	-0.4	-0.6	-1.1	0.6	-0.5	-0.6	-0.5	-0.6	-0.5	-0.8	-0.5	-0.2	-0.5
Leg pain on walking	0.7	0.9	1.5	1.0	1.2	0.3	1.1	1.0	-0.9	1.2	1.0	1.1	1.1	1.2	0.2	1.2	0.7	0.3
Qualifications: NVQ or HND or HNC or equivalent	9.9	11.9	17.8	3.7	3.7	3.8	3.6	2.1	-3.6	3.6	3.2	3.5	3.5	3.1	4.2	3.4	3.5	2.8
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.4	-0.5	-0.0	-0.4	-0.0	-0.4	0.4	-0.1	-0.1	-0.0	-0.1	-0.0	-0.6	0.0	-0.0	0.6
Illness, injury, bereavement, stress in last 2 years	5.0	6.1	9.3	-1.9	-2.2	-2.4	-2.7	-1.7	2.3	-2.6	-2.5	-2.5	-2.6	-3.0	-1.2	-3.1	-3.0	-2.6
Medication: Aspirin	0.3	0.3	1.4	0.2	0.7	0.4	0.6	0.3	-0.3	0.6	0.6	0.7	0.6	0.3	1.2	0.6	0.5	0.4
Supplements: Vitamin C	0.1	0.1	0.5	-0.3	0.4	-0.3	0.2	0.6	-0.1	0.3	0.3	0.3	0.3	0.2	0.7	0.3	0.3	0.5
Knee pain experienced in last month	0.2	0.4	0.8	-0.9	-0.5	-0.2	-0.7	-0.2	0.3	-0.8	-0.8	-0.8	-0.7	-0.7	0.2	-0.6	-0.6	0.3
Hypertension (Self-reported)	0.0	0.1	0.7	-0.4	-0.1	0.0	-0.1	-0.8	-0.3	-0.1	-0.3	-0.2	-0.2	-0.3	0.4	-0.0	-0.1	-0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	1.0	0.5	-0.1	0.1	-0.3	-0.3	-0.6	-0.0	-0.2	-0.1	-0.0	0.1	1.0	-0.1	0.2	0.1
Illnesses of father: Heart disease	0.2	0.2	0.5	-0.6	-0.5	0.3	-0.5	0.3	0.4	-0.5	-0.7	-0.6	-0.5	-0.1	-0.4	0.1	-0.1	-0.6
Illnesses of siblings: Diabetes	0.2	0.3	1.6	-1.0	0.1	0.5	0.0	-1.3	-0.0	-0.2	-0.2	-0.0	-0.0	0.4	-0.4	0.2	0.2	0.7
Smoking status: Previous	5.9	8.8	14.8	2.2	3.0	2.8	3.0	2.8	-3.1	3.1	2.9	3.1	2.9	3.0	2.4	3.2	2.8	3.9
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	1.2	0.0	0.8	0.5	0.6	-0.4	-0.6	0.7	0.6	0.6	0.6	0.1	1.1	0.2	0.5	1.1
Whole body fat-free mass	3.5	19.8	23.2	4.2	4.8	4.3	4.5	3.7	-4.8	4.5	4.4	4.5	4.6	4.2	4.5	4.5	4.6	4.4
Leg fat-free mass (right)	3.6	19.4	23.8	4.2	4.7	4.4	4.5	3.8	-4.9	4.5	4.4	4.5	4.6	4.2	4.3	4.4	4.5	4.2
Arm fat percentage (left)	7.4	29.5	33.3	5.2	5.8	4.9	5.6	4.6	-5.8	5.6	5.5	5.5	5.7	5.5	5.0	5.7	5.6	5.3
Average weekly red wine intake	3.8	5.6	7.8	-2.6	-2.4	-2.2	-2.5	-1.8	2.3	-2.5	-2.3	-2.4	-2.5	-2.7	-2.5	-2.6	-2.8	-0.7
Handedness (chirality/laterality): Left-handed	3.2	3.9	6.0	1.2	1.8	2.2	2.2	1.0	-2.1	2.1	2.0	2.1	2.2	2.4	0.8	2.3	2.4	1.5
Mood swings	0.1	0.2	1.3	0.6	-0.3	0.1	-0.2	1.2	-0.1	-0.1	-0.3	-0.2	-0.1	0.7	-0.2	0.3	0.2	0.6
Loneliness, isolation	3.2	4.4	7.1	1.3	2.2	2.3	2.0	1.7	-2.1	2.0	2.0	2.0	2.1	2.0	2.2	2.0	2.7	2.5
Long-standing illness, disability or infirmity	2.7	4.2	6.5	-2.5	-2.3	-1.7	-2.1	-1.5	2.5	-2.2	-2.4	-2.2	-2.3	-1.5	-2.1	-1.6	-1.7	-1.2
Ever had bowel cancer screening	6.5	7.6	11.9	-3.3	-2.8	-2.2	-2.9	-1.6	2.6	-2.9	-2.7	-2.9	-3.0	-2.6	-3.5	-2.8	-2.6	-2.3
Diabetes diagnosed by doctor	0.2	0.3	0.8	0.5	0.4	0.5	0.6	0.1	-0.3	0.5	0.4	0.5	0.4	0.6	-0.4	0.8	0.4	0.9
Ever had stillbirth, spontaneous miscarriage or termination	2.5	2.6	4.0	1.3	1.5	1.8	1.6	2.0	-1.7	1.6	1.6	1.7	1.7	1.4	1.7	1.4	1.8	1.4
Friendships satisfaction	0.7	0.8	2.4	-1.6	-0.6	-0.7	-0.8	-1.4	0.8	-0.8	-1.0	-0.8	-0.9	-1.0	-0.4	-0.9	-0.7	-0.3
Qualifications: nursing, teaching	1.6	2.5	4.7	-1.9	-1.1	-1.6	-1.7	-0.8	1.3	-1.6	-1.7	-1.5	-1.5	-2.1	-0.4	-2.2	-2.0	-1.3
Commuting to job workplace: Walk	0.2	0.2	0.9	0.3	0.2	-0.2	-0.1	-1.0	0.1	-0.1	-0.1	-0.2	-0.2	-0.7	0.5	-0.5	-0.1	-0.6
Eye problems/disorders: Cataract	0.2	0.2	1.3	-0.5	0.2	0.8	0.3	0.1	-0.2	0.2	0.0	0.1	0.2	0.4	1.1	0.6	0.6	0.2
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	3.8	1.0	0.7	0.4	1.2	1.9	-0.7	1.2	1.0	1.1	1.0	0.9	-0.4	0.9	0.7	-0.1
Medication for cholesterol	0.0	0.1	0.4	0.2	0.2	-0.0	0.1	0.4	0.1	0.0	0.1	0.1	0.2	0.6	0.1	0.3	0.3	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.3	-0.6	-0.3	0.1	-0.4	-0.1	0.1	-0.5	-0.3	-0.5	-0.5	-0.1	-0.4	-0.2	-0.4	0.5
Back pain experienced in last month	0.5	0.7	2.1	1.3	0.6	0.6	0.6	1.4	-0.4	0.6	0.5	0.6	0.7	1.2	1.0	1.0	0.8	0.1
Mineral and other dietary supplements	1.0	1.4	2.6	-0.7	-0.9	-1.2	-0.9	-1.6	1.2	-0.9	-1.2	-0.9	-1.1	-1.5	-1.2	-1.2	-1.4	-1.1
Breast cancer (self-reported)	3.1	3.7	6.6	2.4	1.6	1.8	1.7	2.6	-2.2	1.7	1.7	1.7	1.8	2.0	1.7	2.0	1.8	1.9
Asthma (self-reported)	0.1	0.2	0.8	0.7	-0.2	0.2	0.2	0.6	-0.3	0.2	-0.1	0.1	0.2	0.8	0.9	0.5	0.4	-0.6
Osteoporosis (self-reported)	3.8	4.7	7.8	-1.9	-2.5	-1.5	-2.4	-2.1	2.1	-2.5	-2.0	-2.3	-2.3	-2.2	-2.8	-2.4	-1.7	-1.6
Osteoarthritis (self-reported)	0.3	0.4	2.0	-0.9	-0.8	0.0	-0.6	-0.1	0.5	-0.6	-0.6	-0.7	-0.5	0.1	0.3	-0.1	-0.2	-1.4
Medication: Aspirin	0.0	0.1	0.5	-0.4	0.0	-0.2	-0.0	-0.1	0.3	-0.0	-0.1	0.0	-0.1	-0.4	0.7	-0.1	-0.2	-0.1
Medication: Gliclazide	1.3	1.4	2.1	0.4	1.3	1.1	1.4	0.0	-1.1	1.4	1.4	1.4	1.4	1.4	0.8	1.4	1.0	1.3
Illnesses of father: None of the above (group 1)	0.2	0.2	0.8	-0.6	-0.2	-0.9	-0.3	-0.4	0.1	-0.2	-0.2	-0.2	-0.1	-0.6	-0.0	-0.8	-0.7	-0.4
Smoking status: Current	1.5	2.4	4.6	1.2	1.5	2.1	1.6	0.3	-1.4	1.5	1.3	1.5	1.6	1.7	1.4	1.7	2.0	1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.4	3.0	5.8	-0.3	-1.9	-1.6	-1.6	-0.5	1.7	-1.6	-2.0	-1.7	-1.9	-2.3	-2.4	-1.9	-2.1	-1.0
Whole body water mass	3.4	19.6	23.0	4.2	4.7	4.3	4.5	3.7	-4.8	4.5	4.4	4.5	4.6	4.2	4.4	4.5	4.6	4.3
Leg predicted mass (right)	3.6	19.3	23.7	4.2	4.6	4.4	4.4	3.8	-4.9	4.5	4.4	4.5	4.6	4.3	4.3	4.4	4.5	4.2
Arm fat mass (left)	8.9	36.6	41.9	5.8	6.4	5.6	6.2	5.0	-6.5	6.2	6.0	6.2	6.3	6.0	5.8	6.3	6.3	5.8
Number of self-reported non-cancer illnesses	0.7	1.2	2.1	-1.1	-1.2	-0.5	-1.2	-1.1	0.7	-1.3	-1.3	-1.3	-1.2	-1.5	-0.6	-1.3	-1.1	-0.4
Average weekly champagne plus white wine intake	0.8	1.1	1.8	-1.0	-1.0	-1.1	-1.2	-0.4	0.8	-1.0	-1.1	-1.0	-1.0	-1.0	-1.2	-1.0	-1.3	-1.0
Miserableness	0.2	0.4	2.0	0.2	0.2	1.0	0.3	1.4	-0.6	0.3	0.3	0.3	0.5	0.6	0.3	0.5	0.7	0.6
Guilty feelings	0.3	0.4	3.7	0.8	0.6	0.1	0.3	1.9	0.1	0.2	0.2	0.2	0.2	0.4	0.3	0.5	0.3	0.5
Wears glasses or contact lenses	0.2	0.2	1.1	-0.0	0.2	-0.1	0.3	0.9	-0.1	0.4	0.5	0.4	0.4	0.1	-0.4	0.1	0.1	1.1
Ever taken oral contraceptive pill	0.9	0.9	3.5	0.9	0.9	1.1	0.9	1.9	-0.8	0.8	0.8	0.9	0.9	0.7	1.1	0.7	0.8	0.9
Hearing aid user	0.1	0.1	0.7	-0.3	-0.2	0.5	-0.2	-0.8	0.1	-0.3	-0.4	-0.2	-0.4	0.2	0.5	0.0	0.2	0.3
Mother’s age at death	0.5	0.6	2.6	-0.9	-0.9	-0.6	-0.6	-0.0	0.9	-0.7	-0.8	-0.7	-0.7	-0.7	-1.6	-0.7	-0.2	-0.6
Financial situation satisfaction	0.5	0.6	2.3	1.4	0.4	0.7	0.5	0.4	0.0	0.4	0.5	0.5	0.4	1.4	0.4	1.0	1.5	0.0
Tinnitus: Yes, now most or all of the time	0.8	0.9	2.5	-0.0	-1.1	-1.1	-1.1	0.0	0.7	-0.9	-0.9	-1.1	-1.0	-0.9	-0.6	-1.0	-0.9	-1.6
Commuting to job workplace: Public transport	0.1	0.1	1.1	-0.2	-0.1	0.5	-0.1	-0.2	-0.6	-0.0	0.1	-0.1	0.2	0.3	1.1	-0.2	0.1	0.2
Eye problems/disorders: Glaucoma	0.8	0.9	2.2	-1.4	-0.8	-0.6	-0.8	-1.2	0.7	-0.8	-1.0	-1.0	-1.0	-0.8	-0.3	-0.9	-0.9	-1.5
Medication: Blood pressure	0.0	0.1	0.3	0.0	0.3	0.2	0.2	0.2	-0.5	0.3	0.1	0.2	0.2	-0.4	0.6	-0.1	0.3	0.2
Pain type(s) experienced in last month: Hip pain	1.7	2.1	5.0	1.8	1.1	1.4	1.3	2.2	-1.4	1.3	1.2	1.3	1.3	1.6	1.4	1.5	1.5	1.2
Supplements: Fish oil (including cod liver oil)	1.0	1.3	2.1	0.9	0.8	1.0	1.0	1.1	-1.2	1.1	1.4	1.0	1.3	1.4	0.9	1.2	1.5	0.8
High cholesterol (Self-reported)	0.1	0.1	0.6	-0.0	0.2	-0.1	-0.1	-0.7	-0.0	-0.1	-0.2	-0.1	-0.2	-0.5	0.6	-0.4	-0.2	0.3
Medication: Bendroflumethiazide	1.4	2.1	5.4	1.8	1.7	1.3	1.4	0.5	-1.3	1.4	1.3	1.3	1.3	1.1	2.3	1.4	1.6	1.2
Medication: Paracetamol	0.1	0.2	0.6	0.3	-0.5	-0.8	-0.4	0.3	0.6	-0.4	-0.7	-0.4	-0.5	-0.3	0.2	-0.4	-0.6	0.5
Medication: Lisinopril	0.1	0.1	0.3	0.2	-0.1	-0.5	0.0	-0.4	-0.1	0.1	0.3	0.1	0.1	-0.4	0.6	-0.3	-0.2	-0.6
Medication: Atorvastatin	0.2	0.3	1.9	0.5	0.3	-0.4	0.2	0.5	0.2	0.3	0.3	0.2	0.2	0.2	1.0	0.3	0.2	1.4
Illnesses of father: High blood pressure	0.2	0.2	1.1	-0.3	-0.5	0.1	-0.4	-0.1	0.7	-0.4	-0.5	-0.4	-0.4	0.4	-1.1	0.1	0.3	-0.7
Alcohol drinker status: Never	0.4	0.5	1.1	-0.7	-0.6	-0.3	-0.9	-0.6	0.5	-0.9	-1.1	-0.9	-0.8	-0.9	0.0	-0.9	-0.6	-0.1
Ever smoked	7.3	12.9	16.6	2.7	3.7	3.9	3.6	3.2	-3.6	3.5	3.4	3.6	3.6	3.8	3.3	4.0	3.7	4.1
Basal metabolic rate	4.5	25.0	29.3	4.8	5.3	4.9	5.1	4.2	-5.4	5.1	5.0	5.1	5.2	4.8	5.0	5.1	5.2	5.0
Leg fat percentage (left)	10.1	36.4	42.9	5.4	6.5	5.3	6.3	4.9	-6.2	6.2	6.0	6.2	6.3	6.2	6.0	6.5	6.2	5.9
Arm fat-free mass (left)	4.9	24.7	28.6	4.5	5.3	4.8	5.0	4.3	-5.3	5.0	4.9	5.1	5.2	4.6	5.1	5.0	5.1	5.0
Number of operations (self-reported)	2.0	3.0	4.2	-1.6	-1.9	-1.5	-2.0	-1.4	1.7	-1.9	-2.0	-1.9	-2.0	-1.4	-2.0	-1.5	-1.6	-1.5
Average weekly beer plus cider intake	0.5	0.8	2.2	0.9	1.0	1.0	0.8	0.2	-1.0	0.9	0.8	0.8	0.8	0.1	1.5	0.2	0.7	1.2
Irritability	0.7	1.3	3.3	0.5	1.1	1.1	0.9	1.0	-1.0	1.0	0.9	0.9	1.1	1.4	1.8	1.2	1.2	1.1
Risk taking	1.9	2.8	4.2	0.9	1.7	1.3	1.9	0.9	-1.9	2.0	2.0	2.0	2.0	1.6	1.5	1.8	1.8	0.9
Ever had prostate specific antigen (PSA) test	7.0	8.1	10.8	-3.3	-3.1	-2.7	-3.2	-1.8	2.5	-3.0	-3.1	-3.1	-2.9	-2.5	-3.0	-3.0	-2.9	-2.3
Fractured/broken bones in last 5 years	0.9	1.1	2.0	-0.6	-1.4	-0.5	-1.1	-1.1	1.0	-1.2	-1.3	-1.2	-1.1	-1.0	-1.4	-1.0	-0.7	-0.8
Age started oral contraceptive pill	0.2	0.2	0.9	-0.2	-0.3	-0.1	-0.4	-0.7	0.6	-0.5	-0.3	-0.4	-0.5	-1.0	0.6	-0.6	-0.4	-0.5
Diastolic blood pressure, automated reading	0.3	0.9	1.6	1.3	0.9	1.2	0.8	1.0	-1.0	0.8	0.8	0.7	0.8	0.4	1.0	0.8	1.0	1.1
Ever depressed for a whole week	0.0	0.0	0.3	-0.1	-0.2	0.0	-0.0	0.0	0.4	-0.1	-0.1	-0.2	-0.1	0.1	0.4	0.0	0.5	0.0
Unable to work because of sickness or disability	0.2	0.2	0.6	0.1	0.5	0.4	0.3	0.3	-0.1	0.2	0.2	0.2	0.2	0.6	0.8	0.7	0.5	0.7
Commuting to job workplace: Cycle	2.2	2.6	5.7	-1.5	-1.7	-2.4	-1.7	-0.8	1.7	-1.5	-1.5	-1.6	-1.8	-1.3	-1.0	-1.7	-2.1	-1.4
Myopia	0.6	0.9	3.7	-1.3	-0.4	-0.6	-0.4	-0.9	0.7	-0.5	-0.6	-0.4	-0.5	-1.1	-1.9	-0.7	-1.0	-1.5
Vascular/heart problems diagnosed by doctor	0.0	0.1	0.7	0.6	0.2	-0.1	0.2	0.9	0.0	0.2	0.3	0.3	0.3	0.3	-0.1	-0.1	-0.0	0.5
Cholesterol lowering medication	0.2	0.2	1.2	0.5	0.2	0.7	0.2	-0.7	-0.7	0.2	0.3	0.4	0.1	-0.5	-0.2	-0.0	0.0	1.1
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	1.4	0.3	-0.7	-0.2	-0.5	0.3	0.2	-0.4	-0.6	-0.4	-0.5	-0.3	-1.2	-0.4	-0.0	-0.2
Pain experienced in last month	1.1	1.9	5.8	-0.9	-1.3	-1.0	-1.4	-2.4	1.2	-1.4	-0.9	-1.3	-1.3	-1.5	-1.7	-1.5	-1.2	-0.6
Supplements: Calcium	0.2	0.2	1.3	0.7	0.0	0.5	0.0	1.2	0.3	-0.1	0.1	-0.0	0.1	-0.0	-0.3	0.0	0.3	0.9
Basal cell carcinoma (self-reported)	0.7	0.9	2.6	-1.2	-0.4	-1.1	-0.7	-1.0	0.7	-0.5	-0.6	-0.6	-0.7	-1.0	-1.1	-1.1	-1.1	-1.6
Heart attack/myocardial infarction (self-reported)	0.9	1.2	2.4	-0.9	-1.2	-0.4	-1.4	-0.9	1.3	-1.4	-1.4	-1.5	-1.6	-1.0	-0.4	-0.9	-0.7	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.4	0.6	1.5	-0.2	0.5	1.0	0.7	-0.0	-1.2	0.9	0.8	0.8	0.8	0.5	0.7	0.5	0.9	1.0
Heart disease (siblings)	0.1	0.2	1.2	-1.1	-0.1	0.1	-0.2	-0.9	0.1	-0.1	-0.3	-0.1	-0.1	0.3	-0.1	0.0	0.2	0.6
Alcohol drinker status: Previous	0.2	0.2	2.0	0.1	-0.1	0.0	-0.1	-0.5	0.3	-0.1	-0.1	-0.0	-0.1	0.3	-1.4	0.2	0.3	-0.3
Pack years of smoking	0.3	0.4	1.1	0.3	0.5	0.5	0.5	0.8	-0.3	0.5	0.5	0.4	0.6	1.0	0.5	0.7	1.0	-0.3
Impedance of whole body	2.4	12.2	15.5	-3.7	-3.7	-3.4	-3.6	-3.8	3.4	-3.4	-3.3	-3.5	-3.5	-3.8	-3.1	-3.9	-3.7	-2.3
Leg fat mass (left)	11.0	43.0	50.0	6.1	7.1	6.0	6.8	5.4	-6.8	6.8	6.6	6.7	6.9	6.6	6.5	6.9	6.8	6.3
Arm predicted mass (left)	4.5	22.7	26.0	4.3	5.1	4.6	4.9	3.9	-5.1	4.8	4.7	4.9	5.0	4.5	4.7	4.9	5.0	4.9