Best TWAS P=8.31e-09 · Best GWAS P=6.66e-08 conditioned to 0.0139
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | SPTY2D1 | 0.18 | 0.14 | lasso | 5 | 0.14 | 6.7e-12 | -5.3 | 5.3 | 1.1e-07 | -0.96 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Artery Aorta | SPTY2D1 | 0.13 | 0.17 | enet | 10 | 0.16 | 2.5e-09 | 5.4 | 5.8 | 8.3e-09 | -0.59 | 0.01 | 0.99 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | SPTY2D1 | 0.06 | 0.07 | lasso | 2 | 0.06 | 1.5e-07 | 5.4 | 5.4 | 7.5e-08 | -0.52 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | SPTY2D1 | 0.03 | 0.00 | blup | 43 | 0.01 | 2.0e-02 | 5.4 | 5.1 | 3.1e-07 | -0.65 | 0.01 | 0.98 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SPTY2D1 | 0.14 | 0.20 | lasso | 3 | 0.20 | 4.4e-21 | 5.4 | 5.3 | 1.3e-07 | -0.52 | 0.01 | 0.99 | FALSE |