TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Basal metabolic rate
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chr11:17,936,484-19,345,331
Best TWAS P=8.31e-09 · Best GWAS P=6.66e-08 conditioned to 0.0139
18M
18.2M
18.4M
18.6M
18.8M
19M
19.2M
19.4M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Artery Aorta
SPTY2D1
0.13
0.17
enet
10
0.16
2.5e-09
5.4
5.8
8.3e-09
-0.59
0.01
0.99
TRUE
3
The Cancer Genome Atlas
Lung Adenocarcinoma
SPTY2D1
0.06
0.07
lasso
2
0.06
1.5e-07
5.4
5.4
7.5e-08
-0.52
0.01
0.99
FALSE
1
GTEx
Adipose Subcutaneous
SPTY2D1
0.18
0.14
lasso
5
0.14
6.7e-12
-5.3
5.3
1.1e-07
-0.96
0.01
0.99
FALSE
5
The Cancer Genome Atlas
Prostate Adenocarcinoma
SPTY2D1
0.14
0.20
lasso
3
0.20
4.4e-21
5.4
5.3
1.3e-07
-0.52
0.01
0.99
FALSE
4
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
SPTY2D1
0.03
0.00
blup
43
0.01
2.0e-02
5.4
5.1
3.1e-07
-0.65
0.01
0.98
FALSE