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chr11:26,818,083-29,054,545

Best TWAS P=1.25e-22 · Best GWAS P=1.06e-28 conditioned to 6.53e-08

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	NTR	Blood	LIN7C	0.01	0.00	lasso	3	0.01	2.2e-03	10.07	-9.8	1.2e-22	-0.72	0.10	0.82	TRUE
4	GTEx	Esophagus Muscularis	LIN7C	0.14	0.08	enet	11	0.07	5.4e-05	4.09	7.1	1.3e-12	0.60	0.68	0.17	TRUE
1	GTEx	Adipose Subcutaneous	LIN7C	0.08	0.06	lasso	1	0.04	4.1e-04	9.41	9.4	4.9e-21	0.63	0.74	0.14	FALSE
7	GTEx	Thyroid	LIN7C	0.08	0.04	lasso	4	0.04	6.0e-04	9.41	9.3	1.3e-20	0.69	0.53	0.34	FALSE
11	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	LIN7C	0.05	0.02	lasso	3	0.03	2.9e-04	9.78	9.1	1.4e-19	0.63	0.00	0.99	FALSE
3	GTEx	Cells Transformed fibroblasts	LIN7C	0.26	0.22	lasso	6	0.25	1.4e-18	9.41	8.1	4.3e-16	0.62	1.00	0.00	FALSE
10	The Cancer Genome Atlas	Colon Adenocarcinoma	LIN7C	0.10	0.03	blup	32	0.08	2.8e-05	9.70	7.2	4.1e-13	0.57	0.01	0.96	FALSE
5	GTEx	Liver	METTL15	0.18	0.05	lasso	3	0.09	1.9e-03	-0.13	-7.1	1.6e-12	-0.68	0.02	0.82	FALSE
6	GTEx	Nerve Tibial	LIN7C	0.18	0.08	enet	27	0.12	4.2e-09	9.41	6.3	2.9e-10	0.56	0.61	0.36	FALSE
2	GTEx	Brain Putamen basal ganglia	BDNF-AS	0.22	0.17	lasso	4	0.13	5.5e-04	-4.77	6.0	1.5e-09	0.33	0.23	0.05	FALSE
12	The Cancer Genome Atlas	Brain Lower Grade Glioma	LIN7C	0.09	0.12	lasso	2	0.12	2.6e-13	4.05	6.0	1.9e-09	0.52	0.93	0.07	FALSE
9	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	LIN7C	0.04	0.01	lasso	3	0.02	1.0e-02	-2.17	6.0	2.4e-09	0.46	0.02	0.85	FALSE
13	The Cancer Genome Atlas	Thyroid Carcinoma	LIN7C	0.09	0.10	enet	7	0.09	8.1e-09	4.05	5.3	8.7e-08	0.48	0.89	0.11	FALSE