Best TWAS P=9.01e-20 · Best GWAS P=9.76e-30 conditioned to 3.49e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | FAIM2 | 0.09 | 0.00 | bslmm | 336 | 0.03 | 0.00037 | 0.35 | 5.5 | 3.5e-08 | 0.52 | 0.06 | 0.79 | FALSE |
2 | GTEx | Breast Mammary Tissue (Female) | CERS5 | 0.09 | 0.03 | lasso | 3 | 0.05 | 0.01750 | 0.16 | -6.6 | 3.9e-11 | -0.53 | 0.05 | 0.22 | FALSE |
3 | GTEx | Testis | FAIM2 | 0.27 | 0.09 | lasso | 5 | 0.06 | 0.00093 | 9.66 | -9.1 | 9.0e-20 | -0.77 | 0.05 | 0.84 | TRUE |
4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | FAIM2 | 0.02 | 0.00 | blup | 71 | 0.01 | 0.00853 | 0.35 | -5.9 | 3.0e-09 | -0.36 | 0.16 | 0.12 | TRUE |