[Hub]/) : Traits : Basal metabolic rate : ← →

chr14:24,085,100-25,546,115

Best TWAS P=7.97e-14 · Best GWAS P=4.62e-13 conditioned to 0.927

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous ADCY4 0.08 0.04 lasso 3 0.03 3.3e-03 4.9 5.3 1.4e-07 0.62 0.16 0.43 FALSE
2 GTEx Heart Atrial Appendage ADCY4 0.28 0.14 lasso 4 0.10 2.1e-05 6.9 5.8 5.8e-09 0.48 0.02 0.95 TRUE
3 GTEx Lung LTB4R 0.19 0.15 lasso 6 0.12 2.0e-09 4.9 -5.4 6.6e-08 -0.66 0.98 0.02 FALSE
4 GTEx Spleen NFATC4 0.45 0.00 enet 24 0.00 2.5e-01 4.0 -5.5 4.0e-08 -0.22 0.07 0.06 TRUE
5 GTEx Thyroid ADCY4 0.13 0.13 lasso 6 0.09 1.0e-07 4.3 5.7 1.4e-08 0.51 0.17 0.83 FALSE
6 METSIM Adipose ADCY4 0.07 0.03 lasso 5 0.03 2.2e-05 7.0 7.5 8.0e-14 0.71 0.02 0.98 TRUE
7 The Cancer Genome Atlas Bladder Urothelial Carcinoma ADCY4 0.03 0.01 blup 75 0.03 1.1e-03 4.6 5.8 6.4e-09 0.71 0.04 0.80 FALSE
8 The Cancer Genome Atlas Colon Adenocarcinoma ADCY4 0.07 0.02 lasso 4 0.03 4.7e-03 5.0 5.9 4.4e-09 0.70 0.03 0.76 TRUE
9 The Cancer Genome Atlas Brain Lower Grade Glioma ADCY4 0.06 0.06 lasso 6 0.09 3.0e-10 6.2 7.2 4.5e-13 0.75 0.02 0.98 FALSE
10 The Cancer Genome Atlas Lung Adenocarcinoma ADCY4 0.07 0.09 lasso 3 0.08 4.4e-10 5.1 6.3 2.6e-10 0.73 0.83 0.17 FALSE
11 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma LTB4R 0.16 0.05 blup 73 0.08 4.9e-04 3.4 -5.3 1.1e-07 -0.70 0.03 0.49 FALSE
12 The Cancer Genome Atlas Stomach Adenocarcinoma LTB4R 0.04 0.01 blup 73 0.01 4.2e-02 5.9 -5.5 4.4e-08 -0.63 0.01 0.45 FALSE
13 The Cancer Genome Atlas Stomach Adenocarcinoma LTB4R2 0.04 0.04 lasso 1 0.02 2.5e-02 5.9 -5.9 3.0e-09 -0.70 0.04 0.52 FALSE