[Hub]/) : Traits : Basal metabolic rate : ← →

chr14:24,085,100-25,546,115

Best TWAS P=7.97e-14 · Best GWAS P=4.62e-13 conditioned to 0.927

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	METSIM	Adipose	ADCY4	0.07	0.03	lasso	5	0.03	2.2e-05	7.0	7.5	8.0e-14	0.71	0.02	0.98	TRUE
8	The Cancer Genome Atlas	Colon Adenocarcinoma	ADCY4	0.07	0.02	lasso	4	0.03	4.7e-03	5.0	5.9	4.4e-09	0.70	0.03	0.76	TRUE
2	GTEx	Heart Atrial Appendage	ADCY4	0.28	0.14	lasso	4	0.10	2.1e-05	6.9	5.8	5.8e-09	0.48	0.02	0.95	TRUE
4	GTEx	Spleen	NFATC4	0.45	0.00	enet	24	0.00	2.5e-01	4.0	-5.5	4.0e-08	-0.22	0.07	0.06	TRUE
9	The Cancer Genome Atlas	Brain Lower Grade Glioma	ADCY4	0.06	0.06	lasso	6	0.09	3.0e-10	6.2	7.2	4.5e-13	0.75	0.02	0.98	FALSE
10	The Cancer Genome Atlas	Lung Adenocarcinoma	ADCY4	0.07	0.09	lasso	3	0.08	4.4e-10	5.1	6.3	2.6e-10	0.73	0.83	0.17	FALSE
13	The Cancer Genome Atlas	Stomach Adenocarcinoma	LTB4R2	0.04	0.04	lasso	1	0.02	2.5e-02	5.9	-5.9	3.0e-09	-0.70	0.04	0.52	FALSE
7	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ADCY4	0.03	0.01	blup	75	0.03	1.1e-03	4.6	5.8	6.4e-09	0.71	0.04	0.80	FALSE
5	GTEx	Thyroid	ADCY4	0.13	0.13	lasso	6	0.09	1.0e-07	4.3	5.7	1.4e-08	0.51	0.17	0.83	FALSE
12	The Cancer Genome Atlas	Stomach Adenocarcinoma	LTB4R	0.04	0.01	blup	73	0.01	4.2e-02	5.9	-5.5	4.4e-08	-0.63	0.01	0.45	FALSE
3	GTEx	Lung	LTB4R	0.19	0.15	lasso	6	0.12	2.0e-09	4.9	-5.4	6.6e-08	-0.66	0.98	0.02	FALSE
11	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	LTB4R	0.16	0.05	blup	73	0.08	4.9e-04	3.4	-5.3	1.1e-07	-0.70	0.03	0.49	FALSE
1	GTEx	Adipose Subcutaneous	ADCY4	0.08	0.04	lasso	3	0.03	3.3e-03	4.9	5.3	1.4e-07	0.62	0.16	0.43	FALSE