[Hub]/) : Traits : Basal metabolic rate :

chr14:90,643,934-94,495,324

Best TWAS P=1.86e-11 · Best GWAS P=1.29e-12 conditioned to 0.0592

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta RP11-529H20.6 0.20 0.14 lasso 4 0.18 6.4e-10 -4.6 -5.2 1.9e-07 0.05 0.05 0.92 TRUE
2 GTEx Cells Transformed fibroblasts BTBD7 0.16 0.01 lasso 8 0.04 3.6e-04 -6.0 5.8 5.6e-09 -0.02 0.13 0.85 FALSE
3 GTEx Cells Transformed fibroblasts RPS6KA5 0.08 0.07 lasso 2 0.06 5.3e-05 -6.5 6.7 1.9e-11 -0.89 0.05 0.93 TRUE
4 GTEx Colon Sigmoid RPS6KA5 0.16 0.09 lasso 5 0.08 7.1e-04 -5.3 -5.4 7.4e-08 0.81 0.04 0.89 FALSE
5 GTEx Spleen C14orf159 0.30 0.21 lasso 5 0.21 3.6e-06 -5.8 6.7 2.3e-11 -0.81 0.07 0.45 FALSE
6 METSIM Adipose C14orf159 0.04 0.00 blup 464 0.01 4.0e-03 -5.2 5.3 1.4e-07 -0.70 0.06 0.79 FALSE
7 The Cancer Genome Atlas Lung Squamous Cell Carcinoma BTBD7 0.02 0.01 blup 72 0.02 6.8e-03 -5.7 5.2 1.6e-07 -0.01 0.01 0.87 FALSE
8 The Cancer Genome Atlas Testicular Germ Cell Tumors BTBD7 0.11 0.03 blup 72 0.02 8.0e-02 -6.0 5.9 3.1e-09 -0.01 0.02 0.81 TRUE