Best TWAS P=1.14e-08 · Best GWAS P=1.92e-11 conditioned to 0.000373
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Visceral Omentum | RPL9P25 | 0.26 | 0.02 | enet | 27 | 0.07 | 1.3e-04 | -2.7 | -5.6 | 1.8e-08 | 0.01 | 0.72 | 0.02 | TRUE |
2 | GTEx | Breast Mammary Tissue | MAP2K5 | 0.14 | 0.07 | lasso | 5 | 0.09 | 2.8e-05 | -5.3 | 5.3 | 1.5e-07 | -0.62 | 0.07 | 0.93 | FALSE |
3 | GTEx | Muscle Skeletal | MAP2K5 | 0.08 | 0.03 | lasso | 6 | 0.05 | 1.9e-05 | 4.6 | 5.7 | 1.1e-08 | -0.91 | 0.02 | 0.98 | TRUE |