Best TWAS P=1.48e-10 · Best GWAS P=1.91e-05 conditioned to 0.384
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adrenal Gland | SNUPN | 0.17 | 0.05 | enet | 17 | 0.11 | 1.3e-04 | -3.8 | 6.4 | 1.5e-10 | 0.55 | 0.01 | 0.11 | TRUE |
2 | GTEx | Adrenal Gland | PTPN9 | 0.29 | 0.04 | enet | 11 | 0.15 | 4.8e-06 | -3.8 | 5.1 | 2.8e-07 | 0.03 | 0.02 | 0.08 | FALSE |
3 | The Cancer Genome Atlas | Lung Adenocarcinoma | SNUPN | 0.03 | 0.03 | enet | 8 | 0.02 | 9.9e-04 | 4.1 | 5.2 | 2.4e-07 | 0.88 | 0.00 | 0.68 | FALSE |