TWAS
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Usage
Models
Genes
Traits
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Traits
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Basal metabolic rate
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chr15:75,066,008-76,613,093
Best TWAS P=1.48e-10 · Best GWAS P=1.91e-05 conditioned to 0.384
75M
75.2M
75.4M
75.6M
75.8M
76M
76.2M
76.4M
76.6M
0
1
2
3
4
5
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Adrenal Gland
SNUPN
0.17
0.05
enet
17
0.11
1.3e-04
-3.8
6.4
1.5e-10
0.55
0.01
0.11
TRUE
3
The Cancer Genome Atlas
Lung Adenocarcinoma
SNUPN
0.03
0.03
enet
8
0.02
9.9e-04
4.1
5.2
2.4e-07
0.88
0.00
0.68
FALSE
2
GTEx
Adrenal Gland
PTPN9
0.29
0.04
enet
11
0.15
4.8e-06
-3.8
5.1
2.8e-07
0.03
0.02
0.08
FALSE