Best TWAS P=2.08e-08 · Best GWAS P=9.8e-11 conditioned to 0.0505
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | FAM108C1 | 0.02 | 0.01 | bslmm | 542 | 0.01 | 6.1e-03 | -3.2 | 5.4 | 5.9e-08 | 0.54 | 0.06 | 0.53 | TRUE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | FAM108C1 | 0.05 | 0.04 | lasso | 3 | 0.04 | 5.6e-06 | 5.7 | -5.6 | 2.1e-08 | -0.86 | 0.06 | 0.94 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FAM108C1 | 0.07 | 0.02 | lasso | 2 | 0.02 | 1.7e-03 | -3.8 | -5.3 | 1.4e-07 | -0.82 | 0.03 | 0.61 | FALSE |