[Hub]/) : Traits : Basal metabolic rate : ← →

chr16:14,229,099-15,886,243

Best TWAS P=4.07e-14 · Best GWAS P=9.54e-11 conditioned to 0.71

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
19	NTR	Blood	PDXDC1	0.12	0.12	enet	26	0.15	1.3e-46	-6.4	7.6	4.1e-14	-0.88	0.01	0.99	TRUE
1	GTEx	Adipose Subcutaneous	NTAN1	0.05	0.03	lasso	2	0.04	6.7e-04	-6.5	7.0	3.7e-12	-0.97	0.01	0.97	FALSE
10	GTEx	Heart Left Ventricle	RRN3	0.24	0.12	lasso	7	0.17	2.2e-09	5.6	-6.6	4.3e-11	0.44	0.27	0.68	FALSE
5	GTEx	Cells Transformed fibroblasts	RRN3	0.10	0.12	enet	13	0.13	6.3e-10	5.9	6.5	8.6e-11	-0.62	0.26	0.74	FALSE
14	GTEx	Nerve Tibial	NTAN1	0.07	0.00	enet	14	0.00	1.7e-01	5.9	6.5	9.0e-11	-0.21	0.02	0.19	FALSE
18	NTR	Blood	NTAN1	0.01	0.00	bslmm	110	0.00	4.2e-02	5.9	6.4	1.5e-10	-0.25	0.02	0.05	FALSE
13	GTEx	Muscle Skeletal	NTAN1	0.12	0.07	lasso	6	0.09	1.4e-09	5.6	6.2	8.0e-10	-0.49	0.29	0.70	FALSE
3	GTEx	Cells EBV-transformed lymphocytes	RRN3	0.36	0.14	lasso	5	0.20	4.5e-07	5.9	6.1	1.1e-09	-0.65	0.13	0.85	FALSE
12	GTEx	Muscle Skeletal	RRN3	0.18	0.03	enet	17	0.11	5.7e-11	4.3	-6.0	1.6e-09	0.39	0.17	0.70	FALSE
15	GTEx	Skin Sun Exposed Lower leg	RRN3	0.10	0.12	lasso	1	0.11	4.5e-09	5.9	5.8	4.8e-09	-0.52	0.24	0.76	FALSE
16	GTEx	Testis	RRN3	0.10	0.10	lasso	2	0.07	3.9e-04	5.9	5.8	4.8e-09	-0.53	0.09	0.32	FALSE
20	ROSMAP	Brain Pre-frontal Cortex	NTAN1	0.12	0.10	lasso	3	0.11	1.4e-13	5.6	5.8	6.9e-09	-0.52	0.33	0.67	FALSE
11	GTEx	Heart Left Ventricle	NTAN1	0.09	0.04	lasso	3	0.02	2.0e-02	5.9	5.8	7.1e-09	-0.52	0.02	0.72	FALSE
6	GTEx	Colon Transverse	RRN3	0.13	0.00	lasso	5	0.00	1.9e-01	5.6	-5.7	1.5e-08	0.34	0.02	0.32	FALSE
8	GTEx	Heart Atrial Appendage	NOMO1	0.19	0.12	lasso	6	0.10	3.7e-05	5.6	5.7	1.5e-08	-0.52	0.17	0.45	FALSE
9	GTEx	Heart Atrial Appendage	NTAN1	0.10	0.09	lasso	1	0.07	3.7e-04	5.6	5.7	1.6e-08	-0.53	0.04	0.48	FALSE
2	GTEx	Artery Tibial	RRN3	0.11	0.06	lasso	2	0.07	2.0e-06	5.9	5.6	2.3e-08	-0.53	0.24	0.75	FALSE
4	GTEx	Cells EBV-transformed lymphocytes	RP11-958N24.1	0.22	0.02	lasso	5	0.06	4.8e-03	-2.8	5.5	4.5e-08	-0.63	0.02	0.37	FALSE
7	GTEx	Esophagus Mucosa	RRN3	0.13	0.13	lasso	4	0.13	3.2e-09	5.6	5.4	5.5e-08	-0.55	0.29	0.71	FALSE
17	METSIM	Adipose	NTAN1	0.07	0.06	enet	12	0.06	1.7e-09	5.9	5.3	9.8e-08	-0.47	0.29	0.71	FALSE