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chr16:81,485,946-82,901,701

Best TWAS P=3.35e-10 · Best GWAS P=5.44e-10 conditioned to 3.56e-10

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Visceral Omentum	MPHOSPH6	0.32	0.14	lasso	4	0.17	3.5e-09	5.2	5.5	4.5e-08	-0.02	0.01	0.99	FALSE
2	GTEx	Adrenal Gland	MPHOSPH6	0.34	0.25	lasso	3	0.26	8.4e-10	5.7	5.3	8.6e-08	-0.02	0.00	1.00	FALSE
3	GTEx	Artery Aorta	MPHOSPH6	0.32	0.15	lasso	6	0.17	7.8e-10	5.6	5.3	1.1e-07	-0.01	0.01	0.99	FALSE
4	GTEx	Artery Tibial	MPHOSPH6	0.36	0.24	enet	9	0.27	1.9e-21	5.6	5.5	5.1e-08	-0.02	0.00	1.00	FALSE
5	GTEx	Brain Cerebellar Hemisphere	MPHOSPH6	0.49	0.30	enet	12	0.31	8.5e-09	5.7	5.5	4.4e-08	-0.02	0.01	0.99	FALSE
6	GTEx	Brain Cerebellum	MPHOSPH6	0.40	0.36	enet	10	0.39	1.8e-12	4.5	5.3	1.1e-07	-0.03	0.02	0.98	FALSE
7	GTEx	Colon Transverse	MPHOSPH6	0.21	0.16	lasso	3	0.17	1.4e-08	5.6	5.6	2.3e-08	-0.02	0.01	0.99	FALSE
8	GTEx	Esophagus Muscularis	MPHOSPH6	0.36	0.23	lasso	7	0.20	1.7e-12	5.6	5.7	1.6e-08	-0.03	0.00	1.00	FALSE
9	GTEx	Heart Atrial Appendage	MPHOSPH6	0.33	0.19	enet	27	0.21	5.4e-10	5.6	5.5	3.3e-08	-0.03	0.01	0.99	FALSE
10	GTEx	Heart Left Ventricle	MPHOSPH6	0.28	0.24	lasso	3	0.24	8.9e-13	5.6	5.7	1.5e-08	-0.02	0.00	1.00	FALSE
11	GTEx	Lung	MPHOSPH6	0.16	0.10	lasso	4	0.11	8.3e-09	5.7	5.5	3.6e-08	-0.03	0.01	0.99	FALSE
12	GTEx	Muscle Skeletal	MPHOSPH6	0.27	0.19	lasso	7	0.23	1.4e-22	5.7	5.4	7.1e-08	-0.02	0.00	1.00	FALSE
13	GTEx	Nerve Tibial	MPHOSPH6	0.40	0.22	lasso	7	0.28	1.0e-19	5.6	5.8	9.0e-09	-0.03	0.00	1.00	FALSE
14	GTEx	Stomach	MPHOSPH6	0.41	0.10	lasso	7	0.09	3.5e-05	4.9	6.3	3.3e-10	-0.01	0.01	0.98	TRUE
15	GTEx	Testis	MPHOSPH6	0.52	0.32	lasso	11	0.35	2.0e-16	5.6	5.5	4.9e-08	-0.03	0.00	1.00	FALSE
16	GTEx	Thyroid	MPHOSPH6	0.31	0.21	lasso	4	0.26	4.7e-20	5.2	5.6	2.7e-08	-0.02	0.01	0.99	FALSE
17	The Cancer Genome Atlas	Thyroid Carcinoma	MPHOSPH6	0.18	0.16	lasso	3	0.16	5.1e-15	5.7	5.6	2.2e-08	-0.03	0.00	1.00	FALSE