[Hub]/) : Traits : Basal metabolic rate : ← →

chr16:71,070,698-72,569,466

Best TWAS P=8.85e-11 · Best GWAS P=1.88e-12 conditioned to 5.05e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex MARVELD3 0.07 0.05 lasso 3 0.09 5.7e-11 -6.3 -5.5 5.0e-08 0.51 0.30 0.70 FALSE
2 CommonMind Brain Pre-frontal Cortex PHLPP2 0.04 0.01 bslmm 456 0.02 4.7e-04 -5.1 -6.5 8.9e-11 0.57 0.30 0.64 TRUE
3 GTEx Adipose Subcutaneous AP1G1 0.08 0.05 enet 17 0.06 1.0e-05 -5.6 -5.2 1.8e-07 0.52 0.16 0.83 FALSE
4 GTEx Adrenal Gland AP1G1 0.22 0.06 enet 25 0.14 8.0e-06 -6.2 -6.0 1.7e-09 0.58 0.14 0.83 FALSE
5 GTEx Skin Sun Exposed Lower leg AP1G1 0.06 0.00 enet 15 0.01 5.7e-02 -5.6 -5.2 1.9e-07 0.54 0.19 0.60 FALSE
6 GTEx Testis PHLPP2 0.29 0.38 enet 20 0.37 3.0e-17 -6.3 6.1 1.2e-09 -0.64 0.14 0.86 FALSE
7 METSIM Adipose PHLPP2 0.07 0.03 lasso 5 0.06 1.7e-09 3.9 5.5 3.9e-08 -0.46 1.00 0.00 FALSE
8 YFS Blood ATXN1L 0.02 0.02 blup 413 0.02 6.5e-07 3.2 5.2 2.7e-07 -0.45 0.97 0.02 FALSE
9 YFS Blood PHLPP2 0.04 0.03 bslmm 459 0.05 5.5e-16 -6.2 6.0 2.2e-09 -0.52 0.34 0.66 FALSE
10 The Cancer Genome Atlas Esophageal Carcinoma PHLPP2 0.18 0.03 blup 67 0.07 2.9e-03 -6.3 -5.4 6.2e-08 0.56 0.02 0.68 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma AP1G1 0.03 0.03 lasso 4 0.02 2.1e-03 -3.6 -5.2 1.7e-07 0.62 0.02 0.86 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma AP1G1 0.11 0.02 enet 27 0.04 1.2e-04 3.9 -5.8 5.3e-09 0.28 0.08 0.24 FALSE
13 The Cancer Genome Atlas Testicular Germ Cell Tumors PHLPP2 0.11 0.03 lasso 6 0.01 1.2e-01 3.8 5.4 5.3e-08 -0.43 0.04 0.40 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma MARVELD3 0.08 0.01 blup 44 0.06 7.1e-07 -6.2 5.4 6.5e-08 -0.49 0.03 0.94 FALSE