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chr16:71,070,698-72,569,466

Best TWAS P=8.85e-11 · Best GWAS P=1.88e-12 conditioned to 5.05e-05

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	CommonMind	Brain Pre-frontal Cortex	PHLPP2	0.04	0.01	bslmm	456	0.02	4.7e-04	-5.1	-6.5	8.9e-11	0.57	0.30	0.64	TRUE
6	GTEx	Testis	PHLPP2	0.29	0.38	enet	20	0.37	3.0e-17	-6.3	6.1	1.2e-09	-0.64	0.14	0.86	FALSE
4	GTEx	Adrenal Gland	AP1G1	0.22	0.06	enet	25	0.14	8.0e-06	-6.2	-6.0	1.7e-09	0.58	0.14	0.83	FALSE
9	YFS	Blood	PHLPP2	0.04	0.03	bslmm	459	0.05	5.5e-16	-6.2	6.0	2.2e-09	-0.52	0.34	0.66	FALSE
12	The Cancer Genome Atlas	Prostate Adenocarcinoma	AP1G1	0.11	0.02	enet	27	0.04	1.2e-04	3.9	-5.8	5.3e-09	0.28	0.08	0.24	FALSE
7	METSIM	Adipose	PHLPP2	0.07	0.03	lasso	5	0.06	1.7e-09	3.9	5.5	3.9e-08	-0.46	1.00	0.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	MARVELD3	0.07	0.05	lasso	3	0.09	5.7e-11	-6.3	-5.5	5.0e-08	0.51	0.30	0.70	FALSE
13	The Cancer Genome Atlas	Testicular Germ Cell Tumors	PHLPP2	0.11	0.03	lasso	6	0.01	1.2e-01	3.8	5.4	5.3e-08	-0.43	0.04	0.40	FALSE
10	The Cancer Genome Atlas	Esophageal Carcinoma	PHLPP2	0.18	0.03	blup	67	0.07	2.9e-03	-6.3	-5.4	6.2e-08	0.56	0.02	0.68	FALSE
14	The Cancer Genome Atlas	Thyroid Carcinoma	MARVELD3	0.08	0.01	blup	44	0.06	7.1e-07	-6.2	5.4	6.5e-08	-0.49	0.03	0.94	FALSE
11	The Cancer Genome Atlas	Brain Lower Grade Glioma	AP1G1	0.03	0.03	lasso	4	0.02	2.1e-03	-3.6	-5.2	1.7e-07	0.62	0.02	0.86	FALSE
3	GTEx	Adipose Subcutaneous	AP1G1	0.08	0.05	enet	17	0.06	1.0e-05	-5.6	-5.2	1.8e-07	0.52	0.16	0.83	FALSE
5	GTEx	Skin Sun Exposed Lower leg	AP1G1	0.06	0.00	enet	15	0.01	5.7e-02	-5.6	-5.2	1.9e-07	0.54	0.19	0.60	FALSE
8	YFS	Blood	ATXN1L	0.02	0.02	blup	413	0.02	6.5e-07	3.2	5.2	2.7e-07	-0.45	0.97	0.02	FALSE