[Hub]/) : Traits : Basal metabolic rate :

chr16:88,074,533-90,172,696

Best TWAS P=1.95e-14 · Best GWAS P=2.42e-14 conditioned to 0.182

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CTU2 0.10 0.07 lasso 5 0.08 4.0e-10 -4.5 5.4 7.2e-08 -0.43 1.00 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex SPG7 0.14 0.06 blup 445 0.10 3.2e-12 6.4 -5.6 2.0e-08 -0.02 0.01 0.99 FALSE
3 GTEx Adipose Visceral Omentum RPL13 0.19 0.03 lasso 2 0.06 3.0e-04 5.6 -5.4 5.9e-08 0.06 0.05 0.84 FALSE
4 GTEx Artery Aorta RPL13 0.19 0.20 lasso 5 0.17 1.7e-09 6.1 -6.6 3.3e-11 0.05 0.02 0.98 FALSE
5 GTEx Breast Mammary Tissue RPL13 0.09 0.05 enet 7 0.04 5.3e-03 6.9 -6.3 3.1e-10 0.00 0.02 0.94 FALSE
6 GTEx Cells Transformed fibroblasts RPL13 0.10 0.08 enet 8 0.09 3.7e-07 5.7 -6.8 7.7e-12 0.09 0.03 0.97 FALSE
7 GTEx Colon Sigmoid RPL13 0.17 0.18 lasso 1 0.16 3.1e-06 6.1 -6.1 1.2e-09 0.08 0.01 0.98 FALSE
8 GTEx Colon Transverse RPL13 0.23 0.17 lasso 4 0.16 3.7e-08 6.8 -7.7 1.9e-14 0.01 0.01 0.99 TRUE
9 GTEx Esophagus Muscularis RPL13 0.17 0.12 lasso 3 0.11 2.4e-07 6.8 -7.0 3.4e-12 0.06 0.01 0.99 FALSE
10 GTEx Muscle Skeletal RPL13 0.10 0.09 lasso 5 0.10 3.3e-10 6.1 -6.4 1.7e-10 0.08 0.02 0.98 FALSE
11 GTEx Muscle Skeletal SPG7 0.24 0.22 lasso 5 0.23 8.9e-23 -4.8 -6.1 8.0e-10 -0.11 1.00 0.00 FALSE
12 GTEx Nerve Tibial RPL13 0.10 0.07 lasso 3 0.07 2.0e-05 6.5 -6.1 1.1e-09 0.09 0.04 0.96 FALSE
13 GTEx Skin Not Sun Exposed Suprapubic RPL13 0.16 0.15 lasso 4 0.15 2.0e-08 6.5 -6.6 5.3e-11 0.09 0.04 0.96 FALSE
14 GTEx Skin Sun Exposed Lower leg RPL13 0.11 0.13 enet 7 0.12 1.7e-10 5.7 -5.9 4.7e-09 0.06 0.09 0.91 FALSE
15 GTEx Skin Sun Exposed Lower leg SPG7 0.09 0.05 lasso 2 0.03 1.5e-03 6.8 -6.6 3.5e-11 0.08 0.02 0.98 FALSE
16 GTEx Testis RPL13 0.25 0.22 lasso 5 0.21 1.6e-09 6.1 -6.2 6.6e-10 0.09 0.03 0.97 FALSE
17 GTEx Testis RP5-1142A6.2 0.21 0.13 lasso 4 0.12 7.2e-06 -5.2 -6.2 5.0e-10 0.60 0.15 0.33 TRUE
18 GTEx Thyroid RPL13 0.13 0.05 enet 10 0.06 1.4e-05 6.6 -7.2 6.7e-13 -0.02 0.02 0.98 FALSE
19 GTEx Whole Blood SPG7 0.06 0.05 lasso 3 0.05 3.9e-05 6.5 -6.9 5.7e-12 0.01 0.04 0.92 FALSE
20 GTEx Whole Blood CTD-2555A7.3 0.10 0.00 lasso 5 0.01 1.0e-01 3.3 6.3 3.5e-10 -0.19 0.10 0.30 TRUE
21 METSIM Adipose RPL13 0.05 0.05 enet 5 0.05 1.0e-07 6.6 -6.5 8.9e-11 0.07 0.02 0.98 FALSE
22 NTR Blood RPL13 0.02 0.01 bslmm 365 0.01 5.9e-05 6.8 5.9 3.0e-09 -0.12 0.02 0.98 FALSE
23 The Cancer Genome Atlas Bladder Urothelial Carcinoma SPG7 0.05 0.03 lasso 3 0.03 1.8e-03 6.4 -6.3 2.7e-10 0.08 0.02 0.87 FALSE
24 The Cancer Genome Atlas Esophageal Carcinoma RPL13 0.14 0.07 lasso 3 0.04 2.6e-02 6.4 -6.6 4.9e-11 0.07 0.01 0.83 FALSE
25 The Cancer Genome Atlas Glioblastoma Multiforme SNAI3 0.19 0.06 enet 7 0.12 1.6e-04 2.9 -5.9 3.7e-09 0.44 0.00 0.86 TRUE
26 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SPG7 0.05 0.05 lasso 5 0.05 1.9e-06 6.4 -6.4 1.3e-10 0.08 0.03 0.97 FALSE
27 The Cancer Genome Atlas Brain Lower Grade Glioma MGC23284 0.09 0.04 enet 19 0.03 1.7e-04 -4.2 -5.2 1.6e-07 0.45 0.09 0.86 FALSE
28 The Cancer Genome Atlas Brain Lower Grade Glioma SPG7 0.03 0.02 blup 58 0.03 4.1e-04 5.7 -6.8 1.5e-11 -0.01 0.02 0.73 FALSE
29 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma RPL13 0.03 0.01 blup 41 0.02 8.5e-03 6.3 -6.8 1.1e-11 0.01 0.01 0.74 FALSE
30 The Cancer Genome Atlas Pancreatic Adenocarcinoma SPG7 0.11 0.09 lasso 2 0.08 2.5e-04 6.6 -6.7 2.9e-11 0.07 0.02 0.95 FALSE
31 The Cancer Genome Atlas Stomach Adenocarcinoma RPL13 0.04 0.03 blup 41 0.03 2.2e-03 6.1 -7.0 2.5e-12 0.06 0.02 0.87 FALSE
32 The Cancer Genome Atlas Thyroid Carcinoma SPG7 0.10 0.09 lasso 4 0.11 1.9e-10 6.6 -5.8 7.9e-09 0.14 0.01 0.99 FALSE