[Hub]/) : Traits : Basal metabolic rate : ← →

chr16:88,074,533-90,172,696

Best TWAS P=1.95e-14 · Best GWAS P=2.42e-14 conditioned to 0.182

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	GTEx	Colon Transverse	RPL13	0.23	0.17	lasso	4	0.16	3.7e-08	6.8	-7.7	1.9e-14	0.01	0.01	0.99	TRUE
20	GTEx	Whole Blood	CTD-2555A7.3	0.10	0.00	lasso	5	0.01	1.0e-01	3.3	6.3	3.5e-10	-0.19	0.10	0.30	TRUE
17	GTEx	Testis	RP5-1142A6.2	0.21	0.13	lasso	4	0.12	7.2e-06	-5.2	-6.2	5.0e-10	0.60	0.15	0.33	TRUE
25	The Cancer Genome Atlas	Glioblastoma Multiforme	SNAI3	0.19	0.06	enet	7	0.12	1.6e-04	2.9	-5.9	3.7e-09	0.44	0.00	0.86	TRUE
18	GTEx	Thyroid	RPL13	0.13	0.05	enet	10	0.06	1.4e-05	6.6	-7.2	6.7e-13	-0.02	0.02	0.98	FALSE
31	The Cancer Genome Atlas	Stomach Adenocarcinoma	RPL13	0.04	0.03	blup	41	0.03	2.2e-03	6.1	-7.0	2.5e-12	0.06	0.02	0.87	FALSE
9	GTEx	Esophagus Muscularis	RPL13	0.17	0.12	lasso	3	0.11	2.4e-07	6.8	-7.0	3.4e-12	0.06	0.01	0.99	FALSE
19	GTEx	Whole Blood	SPG7	0.06	0.05	lasso	3	0.05	3.9e-05	6.5	-6.9	5.7e-12	0.01	0.04	0.92	FALSE
6	GTEx	Cells Transformed fibroblasts	RPL13	0.10	0.08	enet	8	0.09	3.7e-07	5.7	-6.8	7.7e-12	0.09	0.03	0.97	FALSE
29	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RPL13	0.03	0.01	blup	41	0.02	8.5e-03	6.3	-6.8	1.1e-11	0.01	0.01	0.74	FALSE
28	The Cancer Genome Atlas	Brain Lower Grade Glioma	SPG7	0.03	0.02	blup	58	0.03	4.1e-04	5.7	-6.8	1.5e-11	-0.01	0.02	0.73	FALSE
30	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	SPG7	0.11	0.09	lasso	2	0.08	2.5e-04	6.6	-6.7	2.9e-11	0.07	0.02	0.95	FALSE
4	GTEx	Artery Aorta	RPL13	0.19	0.20	lasso	5	0.17	1.7e-09	6.1	-6.6	3.3e-11	0.05	0.02	0.98	FALSE
15	GTEx	Skin Sun Exposed Lower leg	SPG7	0.09	0.05	lasso	2	0.03	1.5e-03	6.8	-6.6	3.5e-11	0.08	0.02	0.98	FALSE
24	The Cancer Genome Atlas	Esophageal Carcinoma	RPL13	0.14	0.07	lasso	3	0.04	2.6e-02	6.4	-6.6	4.9e-11	0.07	0.01	0.83	FALSE
13	GTEx	Skin Not Sun Exposed Suprapubic	RPL13	0.16	0.15	lasso	4	0.15	2.0e-08	6.5	-6.6	5.3e-11	0.09	0.04	0.96	FALSE
21	METSIM	Adipose	RPL13	0.05	0.05	enet	5	0.05	1.0e-07	6.6	-6.5	8.9e-11	0.07	0.02	0.98	FALSE
26	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SPG7	0.05	0.05	lasso	5	0.05	1.9e-06	6.4	-6.4	1.3e-10	0.08	0.03	0.97	FALSE
10	GTEx	Muscle Skeletal	RPL13	0.10	0.09	lasso	5	0.10	3.3e-10	6.1	-6.4	1.7e-10	0.08	0.02	0.98	FALSE
23	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	SPG7	0.05	0.03	lasso	3	0.03	1.8e-03	6.4	-6.3	2.7e-10	0.08	0.02	0.87	FALSE
5	GTEx	Breast Mammary Tissue	RPL13	0.09	0.05	enet	7	0.04	5.3e-03	6.9	-6.3	3.1e-10	0.00	0.02	0.94	FALSE
16	GTEx	Testis	RPL13	0.25	0.22	lasso	5	0.21	1.6e-09	6.1	-6.2	6.6e-10	0.09	0.03	0.97	FALSE
11	GTEx	Muscle Skeletal	SPG7	0.24	0.22	lasso	5	0.23	8.9e-23	-4.8	-6.1	8.0e-10	-0.11	1.00	0.00	FALSE
12	GTEx	Nerve Tibial	RPL13	0.10	0.07	lasso	3	0.07	2.0e-05	6.5	-6.1	1.1e-09	0.09	0.04	0.96	FALSE
7	GTEx	Colon Sigmoid	RPL13	0.17	0.18	lasso	1	0.16	3.1e-06	6.1	-6.1	1.2e-09	0.08	0.01	0.98	FALSE
22	NTR	Blood	RPL13	0.02	0.01	bslmm	365	0.01	5.9e-05	6.8	5.9	3.0e-09	-0.12	0.02	0.98	FALSE
14	GTEx	Skin Sun Exposed Lower leg	RPL13	0.11	0.13	enet	7	0.12	1.7e-10	5.7	-5.9	4.7e-09	0.06	0.09	0.91	FALSE
32	The Cancer Genome Atlas	Thyroid Carcinoma	SPG7	0.10	0.09	lasso	4	0.11	1.9e-10	6.6	-5.8	7.9e-09	0.14	0.01	0.99	FALSE
2	CommonMind	Brain Pre-frontal Cortex	SPG7	0.14	0.06	blup	445	0.10	3.2e-12	6.4	-5.6	2.0e-08	-0.02	0.01	0.99	FALSE
3	GTEx	Adipose Visceral Omentum	RPL13	0.19	0.03	lasso	2	0.06	3.0e-04	5.6	-5.4	5.9e-08	0.06	0.05	0.84	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CTU2	0.10	0.07	lasso	5	0.08	4.0e-10	-4.5	5.4	7.2e-08	-0.43	1.00	0.00	FALSE
27	The Cancer Genome Atlas	Brain Lower Grade Glioma	MGC23284	0.09	0.04	enet	19	0.03	1.7e-04	-4.2	-5.2	1.6e-07	0.45	0.09	0.86	FALSE