Best TWAS P=1.94e-10 · Best GWAS P=1.32e-08 conditioned to 0.0855
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Male) | CST7 | 0.15 | 0.00 | lasso | 4 | 0.03 | 7.0e-02 | -4.4 | -5.6 | 2.7e-08 | 0.62 | 0.06 | 0.06 | FALSE |
| 2 | GTEx | Skin Not Sun Exposed Suprapubic | PYGB | 0.12 | 0.13 | enet | 13 | 0.14 | 4.2e-08 | 4.2 | -5.2 | 1.6e-07 | 0.28 | 0.60 | 0.21 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | ENTPD6 | 0.32 | 0.10 | bslmm | 432 | 0.12 | 1.8e-15 | 4.2 | 6.4 | 1.9e-10 | -0.70 | 0.64 | 0.33 | TRUE |