TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Basal metabolic rate
:
←
→
chr20:24,230,055-25,937,126
Best TWAS P=1.94e-10 · Best GWAS P=1.32e-08 conditioned to 0.0855
24.2M
24.4M
24.6M
24.8M
25M
25.2M
25.4M
25.6M
25.8M
26M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
ROSMAP
Brain Pre-frontal Cortex
ENTPD6
0.32
0.10
bslmm
432
0.12
1.8e-15
4.2
6.4
1.9e-10
-0.70
0.64
0.33
TRUE
1
GTEx
Breast Mammary Tissue (Male)
CST7
0.15
0.00
lasso
4
0.03
7.0e-02
-4.4
-5.6
2.7e-08
0.62
0.06
0.06
FALSE
2
GTEx
Skin Not Sun Exposed Suprapubic
PYGB
0.12
0.13
enet
13
0.14
4.2e-08
4.2
-5.2
1.6e-07
0.28
0.60
0.21
FALSE