[Hub]/) : Traits : Basal metabolic rate : ← →

chr20:19,649,716-21,919,054

Best TWAS P=4.25e-13 · Best GWAS P=9.94e-15 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex INSM1 0.07 0.00 bslmm 522 0.02 2.2e-03 3.5 5.5 3.7e-08 -0.01 0.08 0.16 TRUE
2 CommonMind Brain Pre-frontal Cortex PLK1S1 0.08 0.01 lasso 3 0.04 1.1e-05 6.4 6.0 2.6e-09 0.82 0.02 0.98 FALSE
3 GTEx Artery Tibial PLK1S1 0.07 0.08 enet 10 0.08 4.0e-07 7.6 7.2 4.3e-13 0.97 0.01 0.99 TRUE
4 GTEx Esophagus Mucosa PLK1S1 0.11 0.11 lasso 5 0.09 7.8e-07 5.7 5.7 1.1e-08 0.83 0.13 0.87 FALSE
5 GTEx Heart Atrial Appendage PLK1S1 0.15 -0.01 lasso 4 0.00 6.1e-01 1.3 5.3 8.9e-08 0.56 0.05 0.41 FALSE
6 GTEx Skin Not Sun Exposed Suprapubic PLK1S1 0.21 0.09 lasso 6 0.12 5.3e-07 7.2 6.2 5.4e-10 0.93 0.07 0.93 FALSE
7 GTEx Skin Sun Exposed Lower leg PLK1S1 0.15 0.13 enet 10 0.15 3.9e-12 5.7 5.3 1.5e-07 0.83 0.91 0.09 FALSE
8 GTEx Testis PLK1S1 0.64 0.34 enet 33 0.39 1.0e-18 5.7 6.4 1.7e-10 0.79 0.71 0.29 FALSE
9 GTEx Whole Blood PLK1S1 0.08 0.04 enet 9 0.02 4.0e-03 5.7 6.5 1.1e-10 0.89 0.07 0.93 FALSE
10 The Cancer Genome Atlas Breast Invasive Carcinoma PLK1S1 0.05 0.07 enet 9 0.07 5.5e-15 5.6 6.2 7.5e-10 0.88 0.15 0.85 FALSE
11 The Cancer Genome Atlas Lung Adenocarcinoma PLK1S1 0.04 0.03 blup 64 0.04 4.0e-05 5.7 6.8 1.1e-11 0.88 0.12 0.87 FALSE
12 The Cancer Genome Atlas Pancreatic Adenocarcinoma PLK1S1 0.09 0.02 blup 64 0.05 3.1e-03 6.4 7.1 1.4e-12 0.78 0.03 0.52 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma PLK1S1 0.19 0.12 enet 14 0.13 4.3e-13 5.7 6.0 1.7e-09 0.80 0.90 0.10 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma PLK1S1 0.06 0.04 lasso 3 0.04 1.5e-04 5.7 5.9 2.9e-09 0.85 0.15 0.60 FALSE