[Hub]/) : Traits : Basal metabolic rate : ← →

chr20:19,649,716-21,919,054

Best TWAS P=4.25e-13 · Best GWAS P=9.94e-15 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Artery Tibial	PLK1S1	0.07	0.08	enet	10	0.08	4.0e-07	7.6	7.2	4.3e-13	0.97	0.01	0.99	TRUE
1	CommonMind	Brain Pre-frontal Cortex	INSM1	0.07	0.00	bslmm	522	0.02	2.2e-03	3.5	5.5	3.7e-08	-0.01	0.08	0.16	TRUE
12	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	PLK1S1	0.09	0.02	blup	64	0.05	3.1e-03	6.4	7.1	1.4e-12	0.78	0.03	0.52	FALSE
11	The Cancer Genome Atlas	Lung Adenocarcinoma	PLK1S1	0.04	0.03	blup	64	0.04	4.0e-05	5.7	6.8	1.1e-11	0.88	0.12	0.87	FALSE
9	GTEx	Whole Blood	PLK1S1	0.08	0.04	enet	9	0.02	4.0e-03	5.7	6.5	1.1e-10	0.89	0.07	0.93	FALSE
8	GTEx	Testis	PLK1S1	0.64	0.34	enet	33	0.39	1.0e-18	5.7	6.4	1.7e-10	0.79	0.71	0.29	FALSE
6	GTEx	Skin Not Sun Exposed Suprapubic	PLK1S1	0.21	0.09	lasso	6	0.12	5.3e-07	7.2	6.2	5.4e-10	0.93	0.07	0.93	FALSE
10	The Cancer Genome Atlas	Breast Invasive Carcinoma	PLK1S1	0.05	0.07	enet	9	0.07	5.5e-15	5.6	6.2	7.5e-10	0.88	0.15	0.85	FALSE
13	The Cancer Genome Atlas	Prostate Adenocarcinoma	PLK1S1	0.19	0.12	enet	14	0.13	4.3e-13	5.7	6.0	1.7e-09	0.80	0.90	0.10	FALSE
2	CommonMind	Brain Pre-frontal Cortex	PLK1S1	0.08	0.01	lasso	3	0.04	1.1e-05	6.4	6.0	2.6e-09	0.82	0.02	0.98	FALSE
14	The Cancer Genome Atlas	Thyroid Carcinoma	PLK1S1	0.06	0.04	lasso	3	0.04	1.5e-04	5.7	5.9	2.9e-09	0.85	0.15	0.60	FALSE
4	GTEx	Esophagus Mucosa	PLK1S1	0.11	0.11	lasso	5	0.09	7.8e-07	5.7	5.7	1.1e-08	0.83	0.13	0.87	FALSE
5	GTEx	Heart Atrial Appendage	PLK1S1	0.15	-0.01	lasso	4	0.00	6.1e-01	1.3	5.3	8.9e-08	0.56	0.05	0.41	FALSE
7	GTEx	Skin Sun Exposed Lower leg	PLK1S1	0.15	0.13	enet	10	0.15	3.9e-12	5.7	5.3	1.5e-07	0.83	0.91	0.09	FALSE