Best TWAS P=6.31e-08 · Best GWAS P=2.59e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | ARFGEF2 | 0.04 | 0.03 | lasso | 12 | 0.02 | 9.8e-05 | 5.2 | -5.4 | 6.3e-08 | -0.98 | 0.02 | 0.97 | TRUE |
| 2 | NTR | Blood | SNORD12B | 0.03 | 0.05 | lasso | 8 | 0.05 | 1.9e-14 | 5.1 | -5.3 | 1.1e-07 | -0.96 | 0.01 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ARFGEF2 | 0.05 | 0.04 | lasso | 5 | 0.05 | 3.2e-06 | 4.8 | -5.2 | 2.3e-07 | -0.94 | 0.01 | 0.98 | FALSE |
| 4 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | C20orf199 | 0.05 | 0.06 | lasso | 4 | 0.06 | 1.0e-04 | 5.1 | 5.1 | 3.0e-07 | 0.92 | 0.00 | 0.95 | FALSE |