[Hub]/) : Traits : Basal metabolic rate :

chr1:201,158,976-202,607,593

Best TWAS P=2.65e-15 · Best GWAS P=8.02e-17 conditioned to 0.121

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous SHISA4 0.09 0.04 lasso 3 0.03 1.5e-03 -6.3 -7.0 3.3e-12 -0.57 0.20 0.35 TRUE
2 GTEx Esophagus Muscularis LMOD1 0.16 0.09 enet 9 0.08 7.8e-06 8.3 -7.7 1.0e-14 -0.98 0.01 0.99 FALSE
3 GTEx Esophagus Muscularis RP11-307B6.3 0.20 0.12 lasso 3 0.12 5.6e-08 8.3 -7.6 3.1e-14 -0.97 0.01 0.99 FALSE
4 METSIM Adipose LMOD1 0.09 0.07 bslmm 496 0.07 4.8e-10 8.2 -7.8 6.2e-15 -0.96 0.02 0.98 FALSE
5 The Cancer Genome Atlas Bladder Urothelial Carcinoma SHISA4 0.03 0.01 enet 5 0.00 2.5e-01 -6.9 -5.4 7.3e-08 -0.56 0.04 0.16 FALSE
6 The Cancer Genome Atlas Breast Invasive Carcinoma LMOD1 0.02 0.01 blup 59 0.02 1.2e-04 8.2 -5.6 2.2e-08 -0.86 0.01 0.96 FALSE
7 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma LMOD1 0.07 0.06 blup 59 0.03 2.1e-02 8.2 -7.5 7.8e-14 -0.90 0.01 0.87 FALSE
8 The Cancer Genome Atlas Brain Lower Grade Glioma LMOD1 0.04 0.07 enet 6 0.05 9.4e-07 -6.9 -7.7 1.4e-14 -0.75 0.25 0.75 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma LMOD1 0.04 0.01 blup 59 0.01 5.7e-02 8.1 -7.9 2.7e-15 -0.83 0.01 0.82 TRUE