TWAS
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Usage
Models
Genes
Traits
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Traits
:
Basal metabolic rate
:
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chr2:176,716,469-177,216,172
Best TWAS P=9.24e-09 · Best GWAS P=1.17e-08 conditioned to 0.0503
176.7M
176.8M
176.9M
177M
177.1M
177.2M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
HOXD11
0.03
0.02
enet
7
0.03
5.8e-04
5.3
-5.7
9.2e-09
-0.78
0.01
0.94
TRUE
1
The Cancer Genome Atlas
Esophageal Carcinoma
HOXD12
0.21
0.05
blup
48
0.13
6.3e-05
4.6
-5.4
5.5e-08
-0.63
0.01
0.60
FALSE