Best TWAS P=5.09e-10 · Best GWAS P=3.4e-12 conditioned to 0.000726
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Hypothalamus | PDE1A | 0.24 | -0.01 | enet | 21 | -0.01 | 0.75800 | 5.3 | 6.2 | 5.1e-10 | 0.59 | 0.08 | 0.21 | TRUE |
| 2 | GTEx | Liver | NCKAP1 | 0.50 | -0.01 | lasso | 10 | 0.01 | 0.14300 | 4.4 | 5.5 | 5.2e-08 | 0.11 | 0.05 | 0.08 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | PDE1A | 0.05 | 0.04 | blup | 206 | 0.04 | 0.00005 | -4.7 | 5.3 | 9.3e-08 | 0.42 | 0.65 | 0.03 | FALSE |