[Hub]/) : Traits : Basal metabolic rate :

chr3:55,894,951-57,412,804

Best TWAS P=5.92e-14 · Best GWAS P=3.76e-12 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous FAM208A 0.12 0.09 enet 11 0.12 1.1e-09 -3.8 5.8 7.3e-09 -0.82 0.04 0.96 FALSE
2 GTEx Brain Hippocampus CCDC66 0.23 0.23 lasso 3 0.20 2.1e-05 -5.4 5.2 1.8e-07 -0.64 0.24 0.18 TRUE
3 GTEx Cells Transformed fibroblasts FAM208A 0.10 0.00 lasso 4 0.00 1.3e-01 -6.7 6.4 1.5e-10 -0.82 0.02 0.95 FALSE
4 GTEx Pituitary CCDC66 0.16 0.16 enet 31 0.12 6.8e-04 -3.2 5.5 3.5e-08 -0.68 0.03 0.90 FALSE
5 GTEx Skin Sun Exposed Lower leg FAM208A 0.06 0.04 lasso 2 0.03 2.0e-03 -5.2 5.2 1.8e-07 -0.65 0.17 0.57 TRUE
6 YFS Blood CCDC66 0.11 0.09 lasso 8 0.11 6.0e-34 -5.5 -5.5 4.1e-08 0.53 0.97 0.03 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma CCDC66 0.09 0.03 lasso 8 0.05 4.2e-11 -4.6 -6.4 1.5e-10 0.54 0.26 0.74 FALSE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CCDC66 0.05 0.05 blup 56 0.06 1.0e-07 -6.7 -7.4 1.0e-13 0.79 0.00 1.00 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C3orf63 0.03 0.01 enet 4 0.01 1.3e-02 -6.7 6.2 6.8e-10 -0.89 0.01 0.87 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CCDC66 0.09 0.05 blup 56 0.06 5.3e-07 -5.5 -5.6 2.5e-08 0.69 0.63 0.36 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma CCDC66 0.16 0.13 enet 12 0.16 3.1e-17 -5.5 -5.2 2.0e-07 0.34 0.91 0.09 FALSE
12 The Cancer Genome Atlas Lung Adenocarcinoma CCDC66 0.05 0.06 blup 56 0.05 9.7e-07 -6.7 -7.5 5.9e-14 0.73 0.00 1.00 TRUE
13 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CCDC66 0.03 0.03 blup 56 0.03 9.6e-05 -4.9 -6.0 1.6e-09 0.51 0.35 0.24 FALSE
14 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CCDC66 0.08 0.01 blup 56 0.07 7.2e-04 -5.5 -5.3 9.1e-08 0.32 0.12 0.08 FALSE
15 The Cancer Genome Atlas Prostate Adenocarcinoma CCDC66 0.15 0.10 enet 11 0.13 7.3e-14 -4.9 -5.5 3.4e-08 0.48 0.94 0.06 TRUE
16 The Cancer Genome Atlas Stomach Adenocarcinoma CCDC66 0.05 0.01 blup 57 0.02 8.4e-03 -4.6 -6.1 8.6e-10 0.55 0.08 0.49 FALSE