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chr3:55,894,951-57,412,804

Best TWAS P=5.92e-14 · Best GWAS P=3.76e-12 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
12	The Cancer Genome Atlas	Lung Adenocarcinoma	CCDC66	0.05	0.06	blup	56	0.05	9.7e-07	-6.7	-7.5	5.9e-14	0.73	0.00	1.00	TRUE
15	The Cancer Genome Atlas	Prostate Adenocarcinoma	CCDC66	0.15	0.10	enet	11	0.13	7.3e-14	-4.9	-5.5	3.4e-08	0.48	0.94	0.06	TRUE
2	GTEx	Brain Hippocampus	CCDC66	0.23	0.23	lasso	3	0.20	2.1e-05	-5.4	5.2	1.8e-07	-0.64	0.24	0.18	TRUE
5	GTEx	Skin Sun Exposed Lower leg	FAM208A	0.06	0.04	lasso	2	0.03	2.0e-03	-5.2	5.2	1.8e-07	-0.65	0.17	0.57	TRUE
8	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CCDC66	0.05	0.05	blup	56	0.06	1.0e-07	-6.7	-7.4	1.0e-13	0.79	0.00	1.00	FALSE
3	GTEx	Cells Transformed fibroblasts	FAM208A	0.10	0.00	lasso	4	0.00	1.3e-01	-6.7	6.4	1.5e-10	-0.82	0.02	0.95	FALSE
7	The Cancer Genome Atlas	Breast Invasive Carcinoma	CCDC66	0.09	0.03	lasso	8	0.05	4.2e-11	-4.6	-6.4	1.5e-10	0.54	0.26	0.74	FALSE
9	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C3orf63	0.03	0.01	enet	4	0.01	1.3e-02	-6.7	6.2	6.8e-10	-0.89	0.01	0.87	FALSE
16	The Cancer Genome Atlas	Stomach Adenocarcinoma	CCDC66	0.05	0.01	blup	57	0.02	8.4e-03	-4.6	-6.1	8.6e-10	0.55	0.08	0.49	FALSE
13	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CCDC66	0.03	0.03	blup	56	0.03	9.6e-05	-4.9	-6.0	1.6e-09	0.51	0.35	0.24	FALSE
1	GTEx	Adipose Subcutaneous	FAM208A	0.12	0.09	enet	11	0.12	1.1e-09	-3.8	5.8	7.3e-09	-0.82	0.04	0.96	FALSE
10	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CCDC66	0.09	0.05	blup	56	0.06	5.3e-07	-5.5	-5.6	2.5e-08	0.69	0.63	0.36	FALSE
4	GTEx	Pituitary	CCDC66	0.16	0.16	enet	31	0.12	6.8e-04	-3.2	5.5	3.5e-08	-0.68	0.03	0.90	FALSE
6	YFS	Blood	CCDC66	0.11	0.09	lasso	8	0.11	6.0e-34	-5.5	-5.5	4.1e-08	0.53	0.97	0.03	FALSE
14	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CCDC66	0.08	0.01	blup	56	0.07	7.2e-04	-5.5	-5.3	9.1e-08	0.32	0.12	0.08	FALSE
11	The Cancer Genome Atlas	Brain Lower Grade Glioma	CCDC66	0.16	0.13	enet	12	0.16	3.1e-17	-5.5	-5.2	2.0e-07	0.34	0.91	0.09	FALSE