Best TWAS P=8.57e-08 · Best GWAS P=1.5e-06 conditioned to 0.547
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | RP11-738E22.3 | 0.07 | 0.04 | lasso | 6 | 0.05 | 7.7e-08 | -4.8 | 5.1 | 2.7e-07 | -0.83 | 0.01 | 0.97 | FALSE |
2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | REST | 0.04 | 0.01 | lasso | 5 | 0.02 | 7.8e-04 | -4.8 | -5.3 | 8.6e-08 | 0.84 | 0.01 | 0.90 | TRUE |