[Hub]/) : Traits : Basal metabolic rate :

chr4:86,236,934-88,430,396

Best TWAS P=9.55e-10 · Best GWAS P=1.54e-09 conditioned to 0.0511

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PTPN13 0.13 0.18 bslmm 418 0.18 6.8e-22 5.3 -5.6 2.4e-08 -0.44 0.28 0.72 FALSE
2 GTEx Artery Aorta MAPK10 0.15 0.17 enet 16 0.17 1.4e-09 5.7 -5.6 1.9e-08 -0.81 0.01 0.99 FALSE
3 GTEx Artery Aorta RP13-514E23.2 0.26 0.09 lasso 6 0.10 2.2e-06 -5.3 -5.3 1.3e-07 -0.05 0.04 0.96 FALSE
4 GTEx Artery Tibial RP13-514E23.2 0.22 0.16 enet 10 0.18 1.2e-13 -5.3 -5.3 8.7e-08 -0.04 0.06 0.94 TRUE
5 GTEx Colon Sigmoid MAPK10 0.25 0.11 lasso 8 0.07 1.6e-03 5.8 -6.1 9.5e-10 -0.74 0.02 0.95 TRUE
6 GTEx Thyroid PTPN13 0.41 0.31 lasso 6 0.30 3.2e-23 5.9 5.8 7.8e-09 0.81 0.01 0.99 FALSE
7 ROSMAP Brain Pre-frontal Cortex PTPN13 0.09 0.03 blup 409 0.07 4.7e-09 5.3 -5.7 1.0e-08 -0.45 0.25 0.75 FALSE