[Hub]/) : Traits : Basal metabolic rate : ← →

chr4:105,373,669-107,092,169

Best TWAS P=1.3e-21 · Best GWAS P=9.76e-24 conditioned to 9.53e-05

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	GTEx	Esophagus Gastroesophageal Junction	PPA2	0.29	0.15	lasso	5	0.14	8.8e-06	-9.8	-9.6	1.3e-21	0.81	0.03	0.94	TRUE
7	GTEx	Esophagus Mucosa	PPA2	0.18	0.06	enet	14	0.12	2.5e-08	7.5	-8.4	3.0e-17	0.68	0.06	0.94	FALSE
11	GTEx	Ovary	PPA2	0.18	0.10	lasso	3	0.14	2.2e-04	-6.9	-8.2	2.5e-16	0.72	0.05	0.71	FALSE
4	GTEx	Brain Cortex	PPA2	0.14	0.09	lasso	9	0.09	1.6e-03	-8.1	-8.2	3.2e-16	0.79	0.05	0.64	FALSE
15	The Cancer Genome Atlas	Thyroid Carcinoma	PPA2	0.04	0.02	blup	84	0.04	6.1e-05	-8.1	-7.4	1.7e-13	0.74	0.14	0.65	FALSE
5	GTEx	Cells Transformed fibroblasts	PPA2	0.11	0.03	lasso	3	0.01	6.5e-02	-6.6	-7.2	6.1e-13	0.59	0.40	0.15	FALSE
2	GTEx	Artery Aorta	PPA2	0.11	-0.01	enet	24	0.01	1.6e-01	-9.8	-7.1	1.5e-12	0.58	0.06	0.47	FALSE
1	CommonMind	Brain Pre-frontal Cortex	PPA2	0.08	0.03	bslmm	429	0.04	2.2e-05	-6.3	-6.9	4.9e-12	0.61	0.06	0.91	FALSE
10	GTEx	Nerve Tibial	PPA2	0.13	0.07	enet	23	0.07	2.1e-05	-6.9	-6.7	1.8e-11	0.63	0.42	0.37	FALSE
12	GTEx	Skin Sun Exposed Lower leg	TET2	0.09	0.01	enet	18	0.02	3.6e-03	-9.9	-6.4	1.2e-10	0.58	0.02	0.91	FALSE
8	GTEx	Heart Atrial Appendage	PPA2	0.15	0.05	lasso	7	0.06	7.4e-04	-8.2	-6.3	3.5e-10	0.70	0.23	0.40	FALSE
3	GTEx	Brain Cerebellum	PPA2	0.22	0.01	lasso	4	0.03	3.7e-02	-6.9	-5.8	8.9e-09	0.55	0.09	0.14	FALSE
9	GTEx	Muscle Skeletal	PPA2	0.19	0.06	enet	28	0.11	8.7e-11	-8.1	-5.6	1.7e-08	0.67	0.79	0.21	FALSE
13	GTEx	Thyroid	PPA2	0.22	0.01	enet	18	0.12	2.9e-09	5.6	-5.3	9.6e-08	0.50	0.73	0.08	FALSE
14	YFS	Blood	PPA2	0.22	0.05	lasso	19	0.12	9.7e-38	-3.0	5.2	2.2e-07	-0.40	1.00	0.00	FALSE