TWAS
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Models
Genes
Traits
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Traits
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Impedance of whole body
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chr7:101,626,640-103,015,677
Best TWAS P=5.21e-09 · Best GWAS P=5.44e-06 conditioned to 0.063
101.6M
101.8M
102M
102.2M
102.4M
102.6M
102.8M
103M
0
1
2
3
4
5
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
GTEx
Nerve Tibial
RASA4DP
0.29
0.04
enet
37
0.11
3.0e-08
3.96
-5.8
5.2e-09
-0.50
0.01
0.34
TRUE
1
GTEx
Breast Mammary Tissue
RASA4DP
0.27
0.10
enet
33
0.08
6.2e-05
4.55
-5.7
1.3e-08
-0.63
0.01
0.88
FALSE
2
GTEx
Esophagus Muscularis
RASA4DP
0.33
0.01
enet
42
0.18
3.9e-11
4.15
-5.6
1.7e-08
-0.51
0.01
0.69
FALSE
3
GTEx
Heart Atrial Appendage
RASA4DP
0.20
0.02
enet
30
0.03
2.2e-02
-0.45
-5.6
2.4e-08
-0.47
0.00
0.13
FALSE