Best TWAS P=5.21e-09 · Best GWAS P=5.44e-06 conditioned to 0.063
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Breast Mammary Tissue | RASA4DP | 0.27 | 0.10 | enet | 33 | 0.08 | 6.2e-05 | 4.55 | -5.7 | 1.3e-08 | -0.63 | 0.01 | 0.88 | FALSE |
2 | GTEx | Esophagus Muscularis | RASA4DP | 0.33 | 0.01 | enet | 42 | 0.18 | 3.9e-11 | 4.15 | -5.6 | 1.7e-08 | -0.51 | 0.01 | 0.69 | FALSE |
3 | GTEx | Heart Atrial Appendage | RASA4DP | 0.20 | 0.02 | enet | 30 | 0.03 | 2.2e-02 | -0.45 | -5.6 | 2.4e-08 | -0.47 | 0.00 | 0.13 | FALSE |
4 | GTEx | Nerve Tibial | RASA4DP | 0.29 | 0.04 | enet | 37 | 0.11 | 3.0e-08 | 3.96 | -5.8 | 5.2e-09 | -0.50 | 0.01 | 0.34 | TRUE |