[Hub]/) : Traits : Impedance of whole body :

chr7:98,774,738-101,051,925

Best TWAS P=2.81e-09 · Best GWAS P=7.21e-09 conditioned to 0.455

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum TRIM4 0.40 0.39 lasso 5 0.40 4.5e-22 -5.0 5.4 8.3e-08 0.75 0.12 0.88 FALSE
2 GTEx Adrenal Gland TRIM4 0.51 0.37 lasso 7 0.48 1.6e-19 -5.0 5.2 2.2e-07 0.77 0.14 0.86 FALSE
3 GTEx Adrenal Gland STAG3L5P-PVRIG2P-PILRB 0.32 0.25 enet 43 0.20 7.0e-08 -3.5 -5.2 1.7e-07 -0.39 0.94 0.03 FALSE
4 GTEx Brain Nucleus accumbens basal ganglia TRIM4 0.14 0.11 lasso 7 0.06 1.1e-02 -5.0 5.3 1.2e-07 0.75 0.06 0.58 FALSE
5 GTEx Breast Mammary Tissue TRIM4 0.35 0.35 enet 22 0.37 6.1e-20 -5.0 5.2 2.2e-07 0.77 0.12 0.88 FALSE
6 GTEx Cells EBV-transformed lymphocytes TRIM4 0.49 0.47 lasso 7 0.47 4.3e-17 -5.0 5.2 2.2e-07 0.76 0.12 0.88 FALSE
7 GTEx Cells EBV-transformed lymphocytes LAMTOR4 0.40 0.19 enet 39 0.21 2.2e-07 -3.9 5.5 4.7e-08 0.29 0.50 0.11 TRUE
8 GTEx Cells Transformed fibroblasts ZKSCAN1 0.23 0.18 lasso 5 0.19 4.9e-14 -5.4 5.3 1.1e-07 0.46 0.01 0.99 FALSE
9 GTEx Esophagus Gastroesophageal Junction TRIM4 0.35 0.24 lasso 10 0.23 7.6e-09 -4.8 5.3 1.5e-07 0.76 0.12 0.88 FALSE
10 GTEx Esophagus Muscularis TRIM4 0.30 0.30 lasso 9 0.29 6.8e-18 -5.0 5.2 2.2e-07 0.74 0.11 0.88 FALSE
11 GTEx Lung TRIM4 0.35 0.35 lasso 3 0.35 5.4e-28 -5.0 5.1 3.0e-07 0.76 0.12 0.88 FALSE
12 GTEx Ovary TRIM4 0.20 0.04 enet 11 0.07 1.1e-02 4.8 5.2 1.9e-07 0.82 0.06 0.76 FALSE
13 GTEx Skin Not Sun Exposed Suprapubic TRIM4 0.18 0.09 enet 17 0.13 1.8e-07 -5.0 5.7 1.5e-08 0.81 0.07 0.93 TRUE
14 GTEx Skin Sun Exposed Lower leg TRIM4 0.39 0.26 lasso 11 0.25 5.5e-21 -5.0 5.4 7.8e-08 0.78 0.10 0.90 FALSE
15 GTEx Skin Sun Exposed Lower leg ZNF3 0.05 0.01 lasso 4 0.01 7.9e-02 5.2 5.2 2.0e-07 0.77 0.05 0.77 FALSE
16 GTEx Stomach TRIM4 0.34 0.27 enet 35 0.28 6.1e-14 -5.0 5.6 1.8e-08 0.75 0.12 0.88 FALSE
17 GTEx Testis PILRB 0.23 0.13 enet 31 0.12 5.4e-06 -3.4 -5.3 1.4e-07 -0.32 0.86 0.07 FALSE
18 GTEx Testis TRIM4 0.42 0.35 lasso 17 0.36 8.6e-17 -5.0 5.3 1.3e-07 0.80 0.10 0.89 FALSE
19 GTEx Vagina TRIM4 0.32 0.19 lasso 7 0.27 6.0e-07 -5.0 5.5 4.9e-08 0.70 0.11 0.74 FALSE
20 GTEx Whole Blood TRIM4 0.12 0.05 lasso 5 0.06 5.9e-06 -4.8 5.6 2.8e-08 0.78 0.06 0.93 FALSE
21 METSIM Adipose TRIM4 0.17 0.22 lasso 13 0.22 3.9e-32 -4.8 5.2 2.3e-07 0.76 0.14 0.86 FALSE
22 The Cancer Genome Atlas Bladder Urothelial Carcinoma TRIM4 0.08 0.18 lasso 6 0.16 8.3e-14 -4.8 5.1 2.8e-07 0.78 0.06 0.94 FALSE
23 The Cancer Genome Atlas Breast Invasive Carcinoma TRIM4 0.09 0.15 lasso 7 0.15 6.3e-30 -5.0 5.2 1.7e-07 0.77 0.06 0.94 FALSE
24 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma TRIM4 0.12 0.10 blup 52 0.09 3.7e-05 -4.8 5.1 3.0e-07 0.79 0.02 0.98 FALSE
25 The Cancer Genome Atlas Colon Adenocarcinoma TRIM4 0.22 0.28 lasso 10 0.29 5.5e-17 -5.3 5.3 1.3e-07 0.77 0.02 0.98 FALSE
26 The Cancer Genome Atlas Glioblastoma Multiforme TRIM4 0.23 0.13 blup 52 0.20 1.4e-06 -5.0 5.4 8.6e-08 0.77 0.03 0.96 FALSE
27 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma AP1S1 0.16 0.05 lasso 3 0.09 7.7e-10 -4.3 -5.2 2.0e-07 -0.18 0.00 0.90 FALSE
28 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma VGF 0.09 0.03 enet 13 0.04 7.1e-05 -4.3 -5.9 2.8e-09 -0.19 0.00 0.27 TRUE
29 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma TRIM4 0.12 0.16 blup 52 0.20 2.0e-11 -4.8 5.3 1.4e-07 0.79 0.06 0.94 FALSE
30 The Cancer Genome Atlas Liver Hepatocellular Carcinoma TRIM4 0.12 0.14 blup 52 0.16 7.2e-08 5.2 5.6 2.8e-08 0.82 0.06 0.94 FALSE
31 The Cancer Genome Atlas Lung Squamous Cell Carcinoma TRIM4 0.09 0.20 lasso 4 0.19 1.7e-21 -5.0 5.2 1.8e-07 0.76 0.06 0.94 FALSE
32 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma TRIM4 0.05 0.04 blup 52 0.03 2.5e-03 -5.0 5.3 1.3e-07 0.78 0.05 0.84 FALSE
33 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma OR2AE1 0.18 0.12 lasso 4 0.11 2.7e-05 -5.0 -5.2 2.0e-07 -0.78 0.02 0.97 FALSE
34 The Cancer Genome Atlas Prostate Adenocarcinoma GJC3 0.03 0.05 lasso 6 0.05 1.5e-05 -5.3 -5.4 8.7e-08 -0.77 0.03 0.96 FALSE
35 The Cancer Genome Atlas Skin Cutaneous Melanoma TRIM4 0.16 0.04 enet 12 0.02 9.1e-02 5.2 5.2 1.6e-07 0.79 0.03 0.48 FALSE
36 The Cancer Genome Atlas Stomach Adenocarcinoma OR2AE1 0.05 0.04 enet 10 0.05 1.9e-04 -5.0 -5.3 1.4e-07 -0.67 0.02 0.85 FALSE
37 The Cancer Genome Atlas Stomach Adenocarcinoma TRIM4 0.12 0.06 blup 52 0.09 5.6e-07 -5.3 5.3 1.1e-07 0.77 0.01 0.99 FALSE
38 The Cancer Genome Atlas Thyroid Carcinoma TRIM4 0.16 0.30 lasso 9 0.30 9.9e-30 -5.0 5.2 1.9e-07 0.77 0.06 0.94 FALSE