Best TWAS P=4.19e-22 · Best GWAS P=5.3e-24 conditioned to 0.000291
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | MMP16 | 0.12 | 0.07 | lasso | 4 | 0.08 | 4.3e-09 | 9.9 | 6.2 | 5.0e-10 | 0.79 | 0.02 | 0.98 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | MMP16 | 0.10 | 0.08 | blup | 131 | 0.05 | 1.3e-03 | 9.8 | 7.8 | 5.2e-15 | 0.79 | 0.02 | 0.97 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | MMP16 | 0.04 | 0.02 | lasso | 3 | 0.03 | 6.3e-05 | 7.8 | 5.8 | 5.4e-09 | 0.79 | 0.01 | 0.95 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | MMP16 | 0.10 | 0.09 | lasso | 4 | 0.08 | 2.9e-08 | 9.9 | 9.7 | 4.2e-22 | 0.84 | 0.02 | 0.98 | TRUE |