TWAS
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About
Usage
Models
Genes
Traits
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Traits
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Impedance of whole body
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chr8:88,801,153-89,582,625
Best TWAS P=4.19e-22 · Best GWAS P=5.3e-24 conditioned to 0.000291
88.8M
88.9M
89M
89.1M
89.2M
89.3M
89.4M
89.5M
89.6M
0
5
10
15
20
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Thyroid Carcinoma
MMP16
0.10
0.09
lasso
4
0.08
2.9e-08
9.9
9.7
4.2e-22
0.84
0.02
0.98
TRUE
2
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
MMP16
0.10
0.08
blup
131
0.05
1.3e-03
9.8
7.8
5.2e-15
0.79
0.02
0.97
FALSE
1
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
MMP16
0.12
0.07
lasso
4
0.08
4.3e-09
9.9
6.2
5.0e-10
0.79
0.02
0.98
FALSE
3
The Cancer Genome Atlas
Lung Adenocarcinoma
MMP16
0.04
0.02
lasso
3
0.03
6.3e-05
7.8
5.8
5.4e-09
0.79
0.01
0.95
FALSE