TWAS
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Traits
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Traits
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Impedance of whole body
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chr10:26,751,003-28,172,343
Best TWAS P=4.83e-08 · Best GWAS P=1.12e-07 conditioned to 2.26e-06
26.8M
27M
27.2M
27.4M
27.6M
27.8M
28M
28.2M
0
2
4
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Pituitary
MASTL
0.35
0.44
enet
39
0.39
8.4e-11
-4.7
5.5
4.8e-08
-0.11
0.11
0.87
TRUE
1
GTEx
Colon Sigmoid
MASTL
0.27
0.30
lasso
14
0.27
6.0e-10
-4.5
5.3
1.2e-07
-0.05
0.11
0.88
FALSE
4
The Cancer Genome Atlas
Liver Hepatocellular Carcinoma
MASTL
0.13
0.05
blup
60
0.10
3.0e-05
-4.6
5.2
1.5e-07
-0.01
0.02
0.95
FALSE
5
The Cancer Genome Atlas
Thyroid Carcinoma
ANKRD26
0.08
0.04
blup
81
0.07
3.8e-07
-4.7
5.2
1.9e-07
-0.03
0.02
0.96
FALSE
3
The Cancer Genome Atlas
Glioblastoma Multiforme
MASTL
0.14
0.14
blup
60
0.11
2.8e-04
-4.7
5.2
2.1e-07
-0.04
0.02
0.86
FALSE