[Hub]/) : Traits : Impedance of whole body :

chr11:26,818,083-28,416,646

Best TWAS P=2.74e-13 · Best GWAS P=2.92e-34 conditioned to 8.89e-08

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous LIN7C 0.08 0.06 lasso 1 0.04 4.1e-04 -7.0 -7.0 3.0e-12 -0.26 0.86 0.00 FALSE
2 GTEx Brain Putamen basal ganglia BDNF-AS 0.22 0.17 lasso 4 0.13 5.5e-04 5.2 -5.9 4.9e-09 -0.65 0.04 0.81 TRUE
3 GTEx Cells Transformed fibroblasts LIN7C 0.26 0.22 lasso 6 0.25 1.4e-18 -7.0 -5.3 1.2e-07 -0.06 1.00 0.00 FALSE
4 GTEx Thyroid LIN7C 0.08 0.04 lasso 4 0.04 6.0e-04 -7.0 -6.5 6.8e-11 -0.14 0.81 0.01 TRUE
5 NTR Blood LIN7C 0.01 0.00 lasso 3 0.01 2.2e-03 -7.3 6.7 2.0e-11 0.17 0.52 0.01 FALSE
6 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LIN7C 0.05 0.02 lasso 3 0.03 2.9e-04 -7.0 -6.1 1.0e-09 -0.11 0.39 0.02 FALSE
7 The Cancer Genome Atlas Prostate Adenocarcinoma BDNFOS 0.03 0.01 blup 83 0.02 1.4e-03 1.6 -7.3 2.7e-13 -0.76 0.02 0.96 TRUE