Best TWAS P=4.06e-22 · Best GWAS P=2.71e-22 conditioned to 0.00295
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | SLC38A2 | 0.02 | 0.02 | blup | 341 | 0.01 | 0.00581 | 8.7 | -8.6 | 1.2e-17 | -0.90 | 0.04 | 0.93 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | SLC38A2 | 0.10 | 0.06 | blup | 30 | 0.05 | 0.00083 | 9.5 | -9.7 | 4.1e-22 | -0.86 | 0.01 | 0.88 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | ANO6 | 0.08 | 0.00 | blup | 108 | 0.02 | 0.00652 | 4.1 | -5.8 | 8.0e-09 | 0.02 | 0.01 | 0.10 | TRUE |
| 4 | The Cancer Genome Atlas | Soft Tissue Sarcoma | SLC38A2 | 0.06 | 0.01 | blup | 30 | 0.03 | 0.00513 | 9.5 | -8.0 | 1.2e-15 | -0.92 | 0.02 | 0.67 | FALSE |