TWAS
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Usage
Models
Genes
Traits
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Traits
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Impedance of whole body
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chr12:45,363,545-47,465,082
Best TWAS P=4.06e-22 · Best GWAS P=2.71e-22 conditioned to 0.00295
45.5M
46M
46.5M
47M
47.5M
0
5
10
15
20
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
SLC38A2
0.10
0.06
blup
30
0.05
0.00083
9.5
-9.7
4.1e-22
-0.86
0.01
0.88
TRUE
3
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
ANO6
0.08
0.00
blup
108
0.02
0.00652
4.1
-5.8
8.0e-09
0.02
0.01
0.10
TRUE
1
METSIM
Adipose
SLC38A2
0.02
0.02
blup
341
0.01
0.00581
8.7
-8.6
1.2e-17
-0.90
0.04
0.93
FALSE
4
The Cancer Genome Atlas
Soft Tissue Sarcoma
SLC38A2
0.06
0.01
blup
30
0.03
0.00513
9.5
-8.0
1.2e-15
-0.92
0.02
0.67
FALSE