Best TWAS P=3.9e-12 · Best GWAS P=2e-10 conditioned to NaN
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | HOXC6 | 0.03 | 0.02 | blup | 50 | 0.03 | 3.9e-04 | 5.8 | -6.9 | 3.9e-12 | -0.82 | 0.04 | 0.82 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | HOXC8 | 0.03 | 0.05 | enet | 5 | 0.04 | 2.4e-05 | 5.8 | -6.7 | 2.7e-11 | -0.85 | 0.05 | 0.90 | TRUE |
| 7 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | FLJ12825 | 0.15 | 0.02 | lasso | 5 | 0.06 | 8.9e-03 | 5.9 | 6.3 | 3.8e-10 | 0.66 | 0.02 | 0.43 | TRUE |
| 1 | YFS | Blood | CBX5 | 0.02 | 0.01 | lasso | 3 | 0.02 | 2.0e-07 | 6.2 | 5.6 | 2.5e-08 | 0.09 | 0.02 | 0.98 | TRUE |
| 5 | The Cancer Genome Atlas | Rectum Adenocarcinoma | CBX5 | 0.16 | 0.10 | lasso | 4 | 0.11 | 1.5e-03 | 6.2 | 5.3 | 1.2e-07 | 0.02 | 0.01 | 0.70 | TRUE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | LOC400043 | 0.15 | 0.00 | enet | 9 | 0.07 | 4.7e-07 | 3.8 | 5.1 | 3.1e-07 | 0.23 | 0.01 | 0.88 | TRUE |
| 2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | HOXC5 | 0.02 | 0.00 | blup | 51 | 0.01 | 2.4e-02 | 5.7 | 6.7 | 2.9e-11 | 0.67 | 0.02 | 0.31 | FALSE |