[Hub]/) : Traits : Impedance of whole body :

chr12:123,558,705-125,196,704

Best TWAS P=2.56e-11 · Best GWAS P=6.89e-11 conditioned to 1.67e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CCDC92 0.09 0.01 bslmm 438 0.03 3.1e-04 5.5 -6.7 2.6e-11 0.21 0.37 0.56 TRUE
2 GTEx Adipose Subcutaneous RP11-380L11.3 0.09 0.03 lasso 3 0.03 1.4e-03 5.2 5.8 5.1e-09 -0.12 0.52 0.32 FALSE
3 GTEx Adipose Visceral Omentum RP11-380L11.3 0.15 0.03 lasso 5 0.01 1.4e-01 3.4 5.5 4.3e-08 -0.06 0.15 0.10 FALSE
4 GTEx Artery Tibial RP11-380L11.4 0.14 0.12 lasso 4 0.12 2.2e-09 5.2 5.4 7.5e-08 -0.13 0.69 0.31 FALSE
5 GTEx Breast Mammary Tissue (Male) CCDC92 0.06 -0.01 lasso 3 0.00 4.3e-01 5.6 5.2 1.9e-07 -0.09 0.04 0.07 FALSE
6 GTEx Breast Mammary Tissue (Female) CCDC92 0.05 -0.01 enet 2 -0.01 6.2e-01 5.5 5.5 3.2e-08 -0.11 0.05 0.07 FALSE
7 GTEx Esophagus Mucosa CCDC92 0.11 0.02 lasso 4 0.02 1.9e-02 5.5 5.5 4.8e-08 -0.10 0.24 0.47 FALSE
8 GTEx Esophagus Muscularis RP11-380L11.4 0.27 0.29 lasso 8 0.27 1.0e-16 5.2 5.3 1.4e-07 -0.13 0.74 0.26 FALSE
9 GTEx Heart Left Ventricle CCDC92 0.26 0.19 lasso 4 0.21 1.9e-11 5.5 5.7 9.3e-09 -0.10 0.38 0.62 FALSE
10 GTEx Lung RP11-380L11.4 0.07 0.07 lasso 3 0.07 8.2e-06 5.1 5.3 1.1e-07 -0.11 0.56 0.41 FALSE
11 GTEx Muscle Skeletal RP11-380L11.4 0.14 0.03 lasso 8 0.03 4.0e-04 5.2 5.4 8.0e-08 -0.15 0.65 0.26 FALSE
12 GTEx Thyroid ZNF664 0.13 0.06 lasso 11 0.08 6.7e-07 5.5 -5.6 2.1e-08 0.11 0.46 0.54 FALSE
13 METSIM Adipose DNAH10 0.03 0.00 bslmm 475 0.01 3.2e-03 5.3 5.3 8.9e-08 -0.14 0.17 0.11 FALSE
14 The Cancer Genome Atlas Glioblastoma Multiforme CCDC92 0.07 0.02 blup 52 0.04 1.8e-02 5.5 5.2 1.9e-07 -0.11 0.02 0.79 FALSE
15 The Cancer Genome Atlas Soft Tissue Sarcoma CCDC92 0.05 0.03 blup 52 0.03 5.8e-03 4.8 5.5 4.1e-08 -0.12 0.02 0.82 FALSE
16 The Cancer Genome Atlas Thyroid Carcinoma DNAH10 0.04 0.03 lasso 5 0.02 4.6e-03 5.5 5.3 1.1e-07 -0.09 0.02 0.83 FALSE