TWAS hub - CCDC92

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0860	0.0300	7.1e-05	0.013	0.026	0.004	0.026	0.009	7.9e-03	3.2e-04	8.9e-02	3.1e-04	2.7e-02
2	GTEx	Adipose Subcutaneous	0.2260	0.0530	2.7e-10	0.045	NA	0.158	NA	0.133	1.4e-04	NA	6.9e-13	NA	5.8e-11
3	GTEx	Adipose Visceral Omentum	0.1940	0.0540	1.5e-05	0.016	NA	0.070	NA	0.085	4.7e-02	NA	1.7e-04	NA	3.3e-05
4	GTEx	Artery Tibial	0.1904	0.0563	3.8e-05	0.061	NA	0.061	NA	0.052	1.4e-05	NA	1.5e-05	NA	6.4e-05
5	GTEx	Breast Mammary Tissue (Male)	0.0575	0.0942	3.2e-01	-0.012	NA	-0.012	NA	-0.005	8.3e-01	NA	7.4e-01	NA	4.3e-01
6	GTEx	Breast Mammary Tissue (Female)	0.0451	0.0383	1.4e-01	-0.008	NA	-0.007	NA	-0.009	6.8e-01	NA	6.2e-01	NA	7.9e-01
7	GTEx	Cells EBV-transformed lymphocytes	0.2560	0.0800	1.5e-03	0.001	NA	-0.008	NA	-0.004	2.9e-01	NA	7.4e-01	NA	4.7e-01
8	GTEx	Cells Transformed fibroblasts	0.0930	0.0420	6.3e-03	-0.004	NA	0.012	NA	-0.002	9.2e-01	NA	3.8e-02	NA	5.4e-01
9	GTEx	Colon Sigmoid	0.5710	0.0910	5.2e-04	0.053	NA	0.021	NA	0.028	6.0e-03	NA	6.0e-02	NA	3.6e-02
10	GTEx	Esophagus Mucosa	0.1060	0.0470	4.1e-03	0.020	NA	0.009	NA	0.019	1.5e-02	NA	7.9e-02	NA	1.9e-02
11	GTEx	Heart Atrial Appendage	0.1170	0.0470	4.0e-03	0.106	NA	0.112	NA	0.098	1.7e-05	NA	1.1e-05	NA	3.8e-05
12	GTEx	Heart Left Ventricle	0.2578	0.0597	7.6e-08	0.187	NA	0.153	NA	0.210	3.1e-10	NA	1.6e-08	NA	1.9e-11
13	GTEx	Liver	0.2990	0.1050	7.7e-03	0.068	NA	0.063	NA	0.063	6.1e-03	NA	7.9e-03	NA	7.9e-03
14	GTEx	Lung	0.1427	0.0537	3.6e-04	0.001	NA	0.006	NA	0.005	2.4e-01	NA	1.1e-01	NA	1.3e-01
15	GTEx	Nerve Tibial	0.1576	0.0629	1.5e-03	0.010	NA	0.041	NA	0.036	6.3e-02	NA	6.7e-04	NA	1.4e-03
16	GTEx	Prostate	0.3140	0.1000	5.7e-04	0.096	NA	0.113	NA	0.072	2.1e-03	NA	9.0e-04	NA	7.2e-03
17	GTEx	Skin Sun Exposed Lower leg	0.1110	0.0390	4.8e-04	-0.003	NA	0.006	NA	-0.003	8.5e-01	NA	1.0e-01	NA	7.2e-01
18	GTEx	Thyroid	0.0620	0.0250	1.6e-03	0.026	NA	0.011	NA	0.020	4.2e-03	NA	4.7e-02	NA	1.1e-02
19	METSIM	Adipose	0.1030	0.0272	1.3e-09	0.010	0.058	0.057	0.065	0.061	9.3e-03	4.6e-09	5.8e-09	5.5e-10	1.9e-09
20	YFS	Blood	0.0601	0.0175	1.8e-06	0.009	0.017	0.018	0.023	0.015	5.2e-04	2.4e-06	1.2e-06	3.5e-08	5.9e-06
21	TCGA	Glioblastoma Multiforme	0.0720	0.0510	8.1e-03	0.018	0.044	0.005	NA	0.014	9.1e-02	1.8e-02	2.2e-01	NA	1.2e-01
22	TCGA	Kidney Renal Clear Cell Carcinoma	0.0594	0.0386	1.4e-04	0.043	0.044	0.052	NA	0.039	1.1e-05	1.0e-05	1.7e-06	NA	3.2e-05
23	TCGA	Soft Tissue Sarcoma	0.0480	0.0320	3.5e-03	0.031	0.031	0.030	NA	0.023	6.2e-03	5.8e-03	6.6e-03	NA	1.6e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23
Waist Hip Ratio (WHR)	59.8	269.0	600.2	10.3	-20.5	-24.5	-10.6	-18.2	-17.7	-0.2	-11.1	-8.1	-18.3	-17.4	-21.5	-9.5	-20.4	-19.8	-12.0	-14.2	-19.9	-24.2	-7.1	-18.1	-13.4	-15.2
Trunk fat percentage	17.4	69.7	156.2	-5.2	11.6	12.5	4.4	9.2	8.8	4.4	6.3	3.2	9.1	9.3	10.7	1.9	9.2	10.1	7.9	6.9	10.9	11.3	4.3	9.2	6.3	7.9
Arm fat percentage (right)	15.7	62.0	133.2	-4.8	10.6	11.5	4.9	9.0	8.4	2.8	6.2	2.6	8.7	8.9	10.1	0.6	8.3	9.6	7.0	6.8	10.4	10.5	4.5	8.9	6.4	7.4
Arm fat percentage (left)	15.7	62.7	136.9	-4.8	10.9	11.7	4.8	9.0	8.4	3.0	6.0	2.8	8.7	9.0	10.1	0.7	8.8	9.6	7.1	6.6	10.5	10.6	4.5	8.8	6.3	7.3
HDL Cholesterol	15.5	25.9	63.8	-3.3	7.2	8.0	3.0	5.1	5.6	0.2	3.5	2.0	5.7	5.6	6.6	2.4	5.9	5.2	5.0	2.3	6.4	7.8	2.1	5.8	3.9	5.2
Body fat percentage	15.5	61.4	137.2	-4.9	10.9	11.7	4.2	8.7	8.2	3.7	5.8	2.7	8.5	8.7	10.0	1.4	8.7	9.4	7.3	6.6	10.5	10.5	4.1	8.8	5.9	7.4
Hip circumference	11.7	50.4	144.7	-2.1	10.3	12.0	5.6	7.3	6.3	2.0	5.5	3.8	6.8	7.1	8.5	2.0	9.9	9.3	6.4	5.2	9.2	10.3	4.8	7.0	4.4	5.0
Trunk fat mass	10.9	46.6	116.6	-3.0	9.8	10.8	4.1	7.3	6.6	4.5	5.3	3.2	7.0	7.3	8.4	0.9	8.2	8.6	6.7	5.0	9.1	9.3	4.4	7.1	4.5	5.7
Impedance of arm (right)	10.9	51.0	90.2	-8.2	8.0	8.3	2.7	8.9	8.9	5.6	4.6	0.9	8.9	8.1	9.5	3.2	4.6	8.1	6.8	5.6	8.1	8.7	2.9	8.6	7.0	8.4
Impedance of arm (left)	10.4	48.2	87.4	-8.1	7.8	8.2	2.2	8.6	8.6	5.7	4.0	0.7	8.6	8.2	9.4	3.3	4.8	7.9	6.6	5.3	7.8	8.5	2.9	8.3	6.5	8.1
Triglycerides	10.2	16.7	33.0	3.9	-4.9	-5.5	-1.2	-4.3	-5.2	0.3	-2.8	-0.3	-5.2	-5.2	-5.7	-1.5	-3.9	-4.0	-3.1	-2.3	-5.4	-5.0	-1.9	-5.3	-3.4	-5.0
Commuting to job workplace: Walk	9.3	10.0	16.3	-2.5	3.0	3.3	2.6	4.0	3.6	1.7	3.0	0.5	3.9	3.8	3.8	1.5	1.9	4.0	3.6	3.8	3.3	4.0	1.8	3.8	2.8	3.2
Leg fat percentage (right)	9.0	32.7	74.9	-3.5	8.3	8.7	3.3	6.3	5.8	2.4	4.0	2.5	6.1	6.1	7.1	0.1	6.8	6.9	5.1	5.0	7.8	7.7	3.5	6.2	4.3	5.0
Whole body fat mass	8.7	36.4	94.1	-2.4	8.7	9.7	3.9	6.4	5.7	3.8	4.7	2.8	6.0	6.4	7.4	0.5	7.4	7.6	6.1	4.4	8.2	8.3	4.3	6.2	3.9	4.7
Leg fat percentage (left)	8.6	31.1	72.9	-3.2	8.2	8.5	3.2	6.0	5.5	2.1	4.2	2.3	5.8	6.1	6.9	0.5	6.8	6.7	5.0	5.4	7.6	7.7	3.2	5.9	3.8	4.8
Arm fat mass (right)	7.7	31.6	82.5	-1.8	8.1	9.1	4.2	6.0	5.3	2.7	4.7	2.6	5.6	6.0	6.8	-0.3	6.8	7.2	5.3	4.3	7.6	7.7	4.2	5.8	3.8	4.3
Arm fat mass (left)	7.6	31.1	83.7	-1.7	8.1	9.1	4.0	5.9	5.1	2.8	4.4	2.8	5.5	5.9	6.7	-0.1	7.1	7.2	5.2	4.2	7.5	7.7	4.2	5.6	3.6	4.0
Heel bone mineral density (BMD) T-score, automated (left)	7.5	17.1	33.0	-4.7	3.6	5.0	2.9	5.2	5.3	0.3	2.1	0.0	5.3	4.7	5.7	-0.0	3.7	5.2	3.5	3.3	4.8	5.4	2.8	4.9	3.8	4.3
Illnesses of father: Heart disease	7.2	10.0	20.5	2.7	-3.4	-3.4	-1.4	-4.1	-3.8	-1.0	-1.3	0.2	-4.1	-4.2	-4.5	-2.3	-3.2	-3.8	-2.0	-3.0	-3.4	-4.3	-1.8	-3.5	-3.4	-2.9
Cholesterol lowering medication	7.2	10.7	22.0	3.6	-2.9	-4.2	-2.5	-3.9	-3.7	-0.2	-0.8	1.1	-3.8	-3.2	-3.9	-2.4	-2.7	-3.3	-4.6	-2.7	-3.5	-4.7	-1.6	-3.8	-3.7	-3.4
Leg fat mass (right)	6.9	26.8	68.5	-1.7	7.7	8.3	3.5	5.4	4.7	2.8	4.0	2.7	5.1	5.4	6.1	-0.3	6.7	6.6	5.2	3.7	7.1	7.1	3.7	5.2	3.4	3.8
Leg fat mass (left)	6.8	26.5	69.1	-1.6	7.8	8.3	3.5	5.3	4.6	2.7	4.1	2.5	5.0	5.5	6.1	-0.1	6.8	6.5	5.2	3.9	7.0	7.1	3.6	5.1	3.2	3.7
Osteoporosis (self-reported)	6.7	8.3	16.5	-2.6	2.7	2.7	2.3	3.9	3.7	-0.3	1.6	0.4	3.8	3.3	4.1	1.7	2.4	3.2	3.1	3.0	2.7	2.9	1.5	3.4	3.6	3.1
Heel bone mineral density (BMD) T-score, automated (right)	6.3	14.5	30.5	-4.9	2.9	4.7	2.1	4.9	4.9	0.4	1.4	-0.1	5.0	4.5	5.5	0.3	3.3	4.2	3.8	2.9	4.0	5.0	2.8	4.5	3.5	4.0
Coronary Artery Disease (CAD)	6.2	7.4	21.2	1.9	-4.6	-3.9	-1.6	-2.9	-2.8	-1.5	-3.1	-1.3	-2.8	-2.4	-3.4	-1.0	-3.4	-3.3	-1.5	-2.3	-3.2	-3.4	-1.5	-2.7	-2.0	-2.5
Diabetes diagnosed by doctor	6.2	10.2	22.3	2.1	-3.8	-4.7	-2.1	-4.0	-3.4	0.5	-1.9	-0.1	-3.7	-3.5	-4.1	-2.1	-4.3	-4.7	-2.3	-1.9	-4.1	-4.2	-1.1	-3.6	-2.2	-3.1
Reaction Time	6.1	11.7	23.2	-4.4	2.9	2.7	3.0	4.8	4.5	1.8	2.4	-0.0	4.6	4.2	4.6	0.1	0.9	4.0	3.9	2.2	3.9	3.0	1.0	4.5	3.2	4.4
Medication: Ibuprofen (e.g. Nurofen)	5.7	7.2	15.7	-1.1	2.3	2.6	2.4	3.4	3.1	0.7	1.4	-0.9	3.2	3.2	3.3	2.7	2.0	3.8	4.0	2.2	3.3	2.6	1.6	3.3	2.5	2.9
Heel T-Score	5.3	42.3	102.0	-5.6	7.8	7.5	5.2	7.5	6.6	-0.1	6.5	1.1	7.0	8.1	8.5	4.9	8.2	7.2	5.8	5.6	6.8	10.1	4.3	6.7	4.3	5.4
Hand grip strength (right)	5.2	14.2	31.1	3.9	-3.2	-3.0	-1.0	-4.3	-5.4	0.5	-3.5	-1.7	-5.2	-4.5	-5.6	-2.8	-2.5	-3.5	-3.0	-3.0	-3.9	-4.1	-0.2	-4.9	-4.7	-5.2
Diabetes (self-reported)	5.0	7.7	19.3	1.6	-3.2	-4.4	-1.5	-3.3	-3.0	0.6	-2.2	-0.4	-3.1	-3.1	-3.6	-1.8	-3.8	-4.0	-1.6	-1.5	-3.6	-3.8	-0.8	-3.1	-1.6	-2.5
Schizophrenia (2018)	4.6	9.6	18.5	-3.0	3.6	2.6	2.3	3.7	4.1	0.2	2.6	-2.0	4.1	3.0	3.9	1.0	1.5	3.6	2.3	2.9	3.9	2.4	0.9	4.1	4.0	4.3
Blood White Count	4.6	34.0	72.4	8.5	-5.7	-7.1	-2.8	-6.6	-7.4	-1.3	-2.0	-0.3	-7.3	-6.2	-7.8	-4.4	-5.4	-6.2	-6.3	-1.1	-6.8	-6.8	-1.5	-7.2	-6.4	-7.0
Alzheimer’s Disease (in father)	4.5	4.8	10.1	-2.2	1.1	2.5	0.8	2.7	3.0	-0.4	1.0	0.1	3.0	2.8	3.1	0.6	1.0	2.0	2.6	1.2	3.2	2.8	1.4	3.1	1.5	2.9
Type 2 Diabetes (T2D) (2018)	4.5	8.4	18.7	1.4	-3.4	-4.3	-1.5	-3.5	-3.2	0.9	-1.1	-0.6	-3.5	-3.2	-3.7	-1.4	-3.5	-4.1	-1.7	-2.7	-3.8	-3.9	-1.3	-3.3	-2.4	-2.7
Hand grip strength (left)	4.4	11.6	27.2	3.4	-2.2	-2.6	-0.2	-4.0	-5.2	1.8	-2.2	-1.4	-5.0	-4.3	-5.2	-1.5	-2.0	-2.7	-2.9	-2.4	-3.6	-3.4	-0.6	-4.8	-4.6	-4.8
Body mass index (BMI)	4.2	17.9	49.8	-0.5	6.4	7.1	3.5	4.2	3.6	0.0	3.8	2.1	3.9	4.4	4.9	-0.4	6.0	5.3	3.3	3.9	5.8	5.9	2.9	4.1	2.5	2.8
Mean time to correctly identify matches	4.2	8.0	15.4	-3.9	2.6	2.3	1.9	3.9	3.7	1.9	1.9	0.7	3.7	3.3	3.9	-0.1	1.3	3.4	3.3	2.0	3.2	2.7	0.0	3.6	2.4	3.6
Body Mass Index (BMI) (2010)	4.1	5.6	12.7	-1.5	2.7	2.6	1.4	3.1	2.6	0.7	1.9	-0.1	2.9	2.9	3.0	0.8	1.9	3.3	0.9	2.8	3.6	2.5	0.9	3.0	2.3	2.6
Illnesses of siblings: Diabetes	4.1	5.1	14.1	0.7	-2.6	-2.9	-1.7	-2.7	-1.9	-0.2	-1.7	-1.2	-2.1	-2.6	-2.7	-0.9	-3.7	-2.7	-1.5	-2.2	-2.8	-3.7	-2.9	-2.1	-0.6	-0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	4.0	4.6	11.1	-1.0	3.0	2.5	2.1	2.5	2.0	1.0	2.9	-0.8	2.1	2.2	2.1	2.9	1.9	3.3	2.2	2.4	2.4	1.9	0.5	2.0	1.7	1.6
BMI	3.9	22.7	51.6	-0.9	6.7	7.2	3.9	5.2	4.8	-0.4	4.6	1.8	5.0	5.3	5.8	0.2	6.2	5.7	3.9	3.9	6.9	6.1	3.1	5.3	3.0	4.0
Eye problems/disorders: Diabetes related eye disease	3.9	4.3	8.9	1.3	-1.7	-3.0	-2.1	-2.9	-2.2	-0.4	-1.5	0.3	-2.4	-2.7	-2.5	-0.7	-1.9	-2.8	-1.8	-2.1	-2.8	-2.5	-1.2	-2.5	-1.0	-2.1
Medication: Allopurinol	3.9	5.2	9.8	1.4	-2.0	-3.0	-1.6	-3.0	-2.9	-1.0	-0.5	-1.1	-3.0	-2.8	-3.1	0.3	-1.5	-3.1	-2.0	0.3	-2.8	-2.7	-1.2	-3.1	-2.4	-2.8
Medication for cholesterol	3.8	5.8	14.9	-2.7	2.2	3.5	0.2	2.6	2.4	2.9	0.5	-0.2	2.5	1.9	2.7	2.1	3.0	2.4	3.8	0.2	2.4	3.9	0.6	2.3	2.3	2.2
Serious illness, injury or assault of a close relative in last 2 years	3.7	4.2	8.7	-1.2	1.1	1.9	2.2	3.0	2.7	0.8	2.7	-0.2	2.5	2.3	2.4	0.5	0.5	2.4	1.5	1.7	2.7	2.5	1.7	2.6	2.0	2.3
Impedance of whole body	3.7	18.8	44.5	-6.7	4.6	4.7	-0.1	5.2	5.5	4.4	1.8	0.0	5.5	4.9	5.7	2.7	2.0	4.3	4.3	3.4	4.5	4.9	1.1	5.2	4.0	5.5
Alzheimer’s Disease (including proxy)	3.5	5.0	10.8	-2.5	1.0	2.5	0.3	2.8	3.1	0.6	2.3	-0.2	3.2	3.1	3.3	-0.0	1.2	2.0	1.1	1.8	2.7	2.8	1.4	3.1	2.0	2.9
Type 2 Diabetes (T2D) (2012)	3.5	4.0	12.2	-0.6	-1.7	-3.5	-2.0	-1.7	-1.4	0.7	-1.6	-1.5	-2.1	-2.1	-2.8	-2.9	-2.8	-2.4	-1.1	-1.4	-2.2	-2.9	-1.5	-1.8	-0.8	-1.2
Ulcerative Colitis	3.5	5.0	11.0	2.4	-1.3	-2.5	-1.2	-2.8	-3.0	-0.4	-1.0	-0.1	-3.2	-2.8	-2.8	-0.2	-1.1	-2.1	-2.4	-0.4	-2.9	-2.2	0.2	-3.2	-3.3	-3.2
Stomach or abdominal pain in last month	3.5	4.4	10.6	-2.6	2.0	2.2	0.9	1.8	2.9	-0.0	0.3	0.7	2.8	1.0	2.7	-0.0	0.8	2.1	2.4	2.0	3.1	1.7	-0.8	2.9	3.0	3.3
Medication: Ibuprofen	3.5	4.2	7.7	-0.2	2.0	2.2	2.0	2.6	2.2	0.8	1.1	-0.4	2.4	2.5	2.5	2.3	1.4	2.8	2.5	1.7	2.6	1.9	1.2	2.6	1.8	2.3
Bipolar Disorder or Schizophrenia	3.4	8.3	20.1	-3.4	3.2	2.5	1.1	3.1	4.1	0.2	1.7	-2.8	4.0	2.8	3.5	0.0	0.4	2.4	1.2	2.9	3.8	1.6	0.5	4.2	4.3	4.5
Schizophrenia (2014)	3.4	7.5	22.1	-3.1	2.0	1.4	1.8	3.2	3.7	0.3	2.1	-2.7	3.8	2.7	3.2	0.8	-0.3	2.4	1.7	2.6	3.9	1.6	0.3	4.1	3.7	4.7
Time employed in main current job	3.3	3.8	6.9	0.5	-2.1	-2.6	-1.7	-2.0	-2.4	1.6	-1.0	0.6	-2.5	-2.6	-2.3	-1.0	-1.2	-1.7	0.3	-1.7	-2.3	-2.4	-0.9	-2.6	-2.6	-2.5
Illnesses of siblings	3.2	4.5	9.5	-1.5	1.1	2.2	1.9	3.1	2.5	1.0	2.0	-0.4	2.7	2.9	2.6	1.2	0.8	2.6	1.3	1.4	2.8	3.0	2.2	2.6	1.4	2.2
Gout (self-reported)	3.2	4.4	9.2	1.5	-1.9	-2.8	-1.5	-3.0	-2.4	-0.2	-0.7	-1.1	-2.5	-2.6	-2.6	-0.4	-1.8	-3.0	-2.7	-0.2	-2.4	-2.6	-1.0	-2.7	-1.5	-2.4
Number of children fathered	3.0	3.4	6.7	1.3	-2.1	-1.6	-1.2	-2.6	-2.2	-0.9	-1.9	0.1	-2.3	-1.9	-2.3	-1.3	-0.8	-2.6	-1.6	-1.3	-1.9	-2.6	-1.1	-2.1	-2.2	-1.9
LDL Cholesterol	2.8	4.4	14.7	3.5	-0.9	-1.1	0.3	-2.2	-3.2	-0.6	0.0	1.2	-3.1	-2.3	-3.0	0.8	0.4	-1.0	-1.1	0.1	-2.6	-1.3	-0.6	-3.3	-2.8	-3.8
Fluid intelligence score	2.8	5.9	13.8	-3.4	0.4	2.3	2.0	3.3	3.6	1.0	1.1	-0.4	3.5	3.5	3.1	-1.2	-0.8	2.0	0.4	1.2	2.7	1.4	1.6	3.7	3.1	3.2
Trunk predicted mass	2.7	15.3	40.8	6.4	-3.5	-2.9	-0.8	-4.6	-5.2	1.3	-2.1	0.7	-5.1	-4.8	-5.1	-2.7	-1.7	-3.1	-2.2	-5.2	-3.6	-4.2	1.2	-5.0	-4.2	-5.7
Illness, injury, bereavement, stress in last 2 years	2.7	3.3	6.5	1.8	-2.3	-1.6	-0.9	-2.3	-2.2	-1.4	-1.8	-0.6	-2.1	-1.6	-2.2	0.6	-1.3	-2.0	-1.3	-2.5	-2.2	-1.9	-1.1	-2.1	-2.3	-1.9
Trunk fat-free mass	2.6	15.1	40.5	6.4	-3.4	-2.9	-0.8	-4.6	-5.2	1.3	-2.1	0.7	-5.0	-4.7	-5.1	-2.7	-1.6	-3.0	-2.2	-5.1	-3.6	-4.2	1.4	-5.0	-4.2	-5.7
Loud music exposure frequency	2.6	2.8	5.8	-1.0	1.7	0.8	1.3	2.2	2.4	1.5	0.6	0.1	2.4	2.1	2.3	0.5	0.7	1.4	1.9	0.6	2.3	0.9	2.0	2.0	2.4	1.7
Headache pain in last month	2.6	4.4	15.1	-2.4	1.3	1.0	1.7	2.4	3.5	-0.6	0.2	0.4	3.1	2.1	2.7	-0.5	-0.2	1.1	1.9	1.7	2.4	0.4	0.4	3.2	3.9	3.3
Weight	2.5	12.4	44.0	1.1	5.5	6.6	2.8	3.0	2.1	3.2	2.8	2.6	2.5	3.0	3.5	-0.7	5.4	4.8	3.3	1.7	4.9	4.8	3.9	2.7	1.0	1.2
Commuting to job workplace: Car/motor vehicle	2.5	2.9	5.7	0.8	-1.5	-1.3	-1.5	-2.1	-2.0	-0.6	-0.9	-0.8	-2.1	-2.4	-2.0	-0.5	-0.2	-1.7	-1.8	-2.0	-2.4	-1.9	-1.8	-2.4	-1.7	-2.0
Medication: Atorvastatin	2.5	3.1	8.6	0.8	-2.6	-2.6	-1.4	-2.1	-1.7	1.0	-1.6	0.1	-1.8	-1.5	-1.9	-0.4	-2.3	-2.1	-0.9	-1.7	-2.2	-2.9	-0.4	-1.7	-1.7	-1.6
Blood Red Count	2.4	23.0	47.4	3.8	-3.2	-6.0	-3.5	-5.5	-6.2	0.8	-4.0	-1.5	-6.2	-6.3	-6.5	-2.5	-3.0	-6.0	-2.8	-2.7	-6.0	-6.9	-2.7	-6.3	-4.5	-5.4
Severe depression (siblings)	2.4	2.7	7.4	-0.4	1.5	2.3	0.8	1.8	2.4	-0.4	0.2	0.2	2.2	2.1	2.0	0.3	0.7	1.6	0.7	1.8	2.7	1.0	0.6	2.5	1.4	2.5
Suffer from ‘nerves’	2.3	3.7	10.6	1.2	-1.7	-1.8	-2.2	-2.5	-1.8	-1.0	-3.3	-0.9	-2.0	-2.3	-2.3	-0.8	-2.2	-3.1	-1.9	-1.4	-1.8	-2.4	-1.8	-1.4	-0.9	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.3	4.8	10.8	-1.4	1.6	2.2	3.3	2.7	2.7	1.0	2.3	-1.1	2.7	3.0	2.5	-0.0	0.2	2.5	2.6	1.9	2.7	2.1	0.9	2.9	1.6	2.7
Allergy or Eczema	2.2	5.8	14.4	-2.3	2.3	2.0	-1.2	2.4	3.0	1.0	3.3	-0.8	2.9	3.2	3.1	0.7	1.4	2.3	1.1	3.8	3.7	1.9	1.2	3.2	1.7	2.8
Hayfever/allergic rhinitis (self-reported)	2.2	3.0	9.0	-1.3	0.4	1.0	-0.1	1.8	2.6	-0.1	0.9	-1.1	2.7	2.0	2.1	-0.4	-0.8	0.4	0.1	2.2	2.5	0.4	0.7	2.7	3.0	2.9
Illnesses of mother	2.2	2.8	9.5	1.4	-1.8	-1.9	0.3	-1.5	-2.2	-0.2	-0.9	-0.6	-2.2	-1.8	-2.2	-0.0	-1.4	-1.5	0.0	-3.1	-2.3	-0.6	0.6	-2.2	-1.5	-2.5
Birth weight of first child	2.2	4.1	9.6	1.6	-2.2	-2.8	-0.1	-2.3	-2.3	-0.6	-1.2	-0.0	-2.4	-2.4	-2.7	-1.1	-1.5	-2.4	-1.6	-2.2	-3.1	-2.6	-2.0	-2.5	-1.1	-1.8
Chronic bronchitis/emphysema (mother)	2.2	2.6	11.4	0.3	2.2	2.1	1.4	1.1	0.9	-0.6	2.0	1.1	1.2	1.1	1.4	1.9	2.6	1.9	0.8	3.4	1.6	1.6	-0.8	1.1	0.8	1.1
Sensitivity / hurt feelings	2.1	3.6	8.8	1.8	-0.7	-1.4	-3.0	-2.7	-2.2	-0.5	-1.7	-0.4	-2.3	-2.2	-2.1	-0.9	-0.9	-2.9	-2.6	-1.1	-2.2	-1.2	-0.6	-2.1	-2.2	-1.7
Father’s age at death	2.1	2.8	8.5	-0.9	1.5	2.0	1.1	2.6	1.6	0.8	0.1	0.9	1.9	2.1	2.1	1.5	2.0	2.9	2.0	1.2	0.9	2.2	1.5	1.6	1.2	0.7
Qualifications: A levels/AS levels or equivalent	2.1	4.6	12.5	-2.0	-0.0	0.5	1.1	3.0	3.5	0.1	2.1	-0.2	3.3	3.2	2.8	-0.2	-0.7	1.8	0.3	1.0	3.1	-0.0	1.5	3.5	2.5	3.2
Arm fat-free mass (right)	2.1	10.9	36.7	6.1	-2.3	-1.6	-0.5	-4.1	-4.7	0.8	-1.7	1.1	-4.4	-3.8	-4.2	-1.7	-0.3	-2.5	-1.9	-4.3	-2.9	-3.2	1.0	-4.3	-3.9	-5.1
Primary Biliary Cirrhosis	2.0	2.8	10.8	0.7	-3.3	-2.8	-1.1	-1.4	-1.1	0.2	-1.6	-0.9	-1.3	-1.3	-1.7	-0.7	-3.2	-2.9	-1.2	-1.1	-1.5	-2.3	-1.1	-1.1	-0.8	-0.2
Medication: Simvastatin	2.0	3.0	9.5	1.8	-1.2	-2.8	-2.5	-1.7	-1.5	1.0	-0.2	0.3	-1.7	-1.6	-1.9	-1.2	-1.7	-1.5	-2.6	-0.7	-1.7	-3.1	-0.9	-1.7	-1.6	-1.3
Number of live births	2.0	2.8	6.5	-2.2	2.5	1.7	0.8	1.9	1.7	0.4	0.3	0.2	1.7	1.7	2.0	1.7	2.0	2.0	2.0	2.2	1.7	2.1	0.0	1.7	0.8	1.8
Medication: Ventolin 100micrograms inhaler	2.0	2.5	7.0	0.9	-1.1	-2.3	-0.8	-1.7	-1.8	0.6	-2.3	-0.6	-1.6	-1.6	-1.9	-1.3	-2.0	-2.6	0.1	-1.6	-2.2	-2.1	-1.0	-1.6	-0.5	-0.9
Number of full sisters	2.0	2.5	8.6	-2.3	1.9	2.2	1.0	1.1	1.7	0.3	0.9	1.8	1.6	0.7	1.8	-0.2	1.3	1.4	2.8	-0.2	1.0	2.9	-0.2	1.1	2.0	1.1
Myopia	2.0	2.9	6.2	-2.3	0.3	-0.2	0.3	2.4	2.2	1.0	1.8	-1.9	2.3	2.5	1.8	-1.2	-1.9	1.6	1.3	1.5	1.6	0.5	1.9	2.1	1.0	1.9
Pain experienced in last month	2.0	3.3	11.2	1.1	-3.3	-2.1	-1.5	-1.1	-1.8	0.9	-0.4	-2.2	-1.6	-0.7	-1.9	-0.7	-2.8	-1.8	-1.0	-1.4	-2.2	-2.7	0.9	-1.8	-2.3	-2.0
Arm predicted mass (right)	1.9	9.8	35.7	6.0	-2.0	-1.3	-0.1	-3.9	-4.5	1.2	-1.3	1.2	-4.2	-3.7	-4.0	-1.8	-0.1	-2.0	-1.3	-4.1	-2.6	-2.8	1.2	-4.1	-3.7	-4.9
Ever had stillbirth, spontaneous miscarriage or termination	1.9	2.0	4.5	-2.1	-0.5	0.4	1.7	1.9	2.0	0.4	1.3	-1.5	1.8	1.9	1.5	0.1	-1.0	1.2	0.7	1.2	1.8	0.5	1.1	2.1	1.3	1.9
Qualifications: nursing, teaching	1.9	2.9	12.3	-1.0	-0.5	1.2	-0.6	1.4	2.6	-2.7	0.3	-0.3	2.3	1.4	1.9	-0.6	-1.0	1.1	-1.0	0.2	2.7	0.0	-1.4	2.9	1.9	3.5
Medication: Blood pressure	1.9	3.7	12.5	2.5	-1.4	-3.0	0.6	-2.3	-1.9	-3.1	-0.6	-0.3	-1.9	-1.5	-2.0	-1.0	-2.1	-2.0	-2.8	0.5	-1.7	-3.5	-0.9	-1.6	-1.1	-1.4
Diabetes (mother)	1.8	2.3	8.9	-0.4	-1.4	-2.3	-0.4	-1.8	-1.0	-0.3	-1.2	-0.7	-1.2	-1.8	-1.8	-1.3	-1.9	-2.6	-1.0	-1.3	-0.8	-2.4	-3.0	-1.0	-0.0	0.2
Medication: Lisinopril	1.8	2.3	7.2	-1.0	-1.5	-2.1	-1.4	-1.1	-1.0	1.7	-2.7	-0.5	-1.1	-1.0	-0.8	-2.7	-1.0	-1.9	-0.3	-2.2	-2.1	-1.8	-0.2	-1.2	-0.9	-1.1
Basal cell carcinoma (self-reported)	1.8	2.1	8.0	-1.8	-2.8	-2.7	-0.6	-0.1	-0.4	1.1	-0.4	-2.4	-0.2	0.1	-0.3	1.3	-2.8	-1.3	0.4	-1.8	-1.1	-2.1	0.3	-0.2	-1.2	-0.0
Alcohol drinker status: Previous	1.8	2.1	6.3	-1.4	2.5	1.6	0.7	1.6	1.8	0.9	0.8	0.3	1.7	1.2	1.9	0.5	1.5	1.4	0.6	1.7	1.8	1.7	0.3	1.6	1.6	1.5
Intelligence (Savage-Jansen 2018)	1.7	5.3	13.4	-3.0	0.5	1.6	1.0	3.5	3.5	0.2	1.0	-0.4	3.7	3.3	3.4	-0.1	0.2	2.5	0.7	1.6	2.4	1.7	1.7	3.1	3.4	2.5
Age at First Birth	1.7	2.5	8.6	0.7	-2.0	-1.5	-1.8	-1.7	-1.6	-1.2	-2.9	-0.5	-1.5	-1.8	-1.7	0.7	-1.1	-2.1	-2.2	-2.0	-1.2	-1.7	-0.7	-1.3	-1.5	-0.9
Hypothyroidism (self reported)	1.7	4.0	10.1	-1.6	2.5	2.1	2.5	2.2	2.2	-0.8	2.6	-0.2	2.4	1.8	2.4	-0.3	1.8	2.3	1.0	0.7	2.3	2.1	0.3	2.2	3.2	2.2
High blood pressure (mother)	1.7	2.3	8.6	-1.1	1.4	1.1	1.0	2.0	2.0	0.6	1.2	-0.2	1.9	2.1	1.6	0.2	-0.1	1.5	1.6	2.9	1.6	0.8	1.4	2.0	1.6	1.5
Alcohol intake versus 10 years previously	1.7	2.5	5.8	1.5	-0.1	-1.8	-1.7	-1.9	-2.1	0.2	-1.3	1.7	-2.0	-2.1	-1.6	-1.5	0.8	-1.8	-2.1	-0.1	-1.7	-0.0	-2.4	-2.2	-0.8	-1.3
Falls in the last year	1.7	2.4	6.0	-1.4	2.0	2.4	-0.3	1.4	2.2	1.2	0.8	-0.0	1.9	1.5	1.9	0.1	1.1	1.3	0.9	1.5	1.8	1.6	0.2	1.9	2.4	1.8
Shortness of breath walking on level ground	1.7	2.0	8.3	1.2	2.9	2.0	2.1	0.3	-0.3	1.0	1.9	2.2	0.0	0.4	0.8	0.5	2.2	1.0	1.0	1.6	1.2	2.3	0.8	0.2	-0.2	-0.1
Pulse rate, automated reading	1.7	5.6	13.5	2.3	-1.9	-2.5	-1.5	-2.6	-2.9	0.5	-2.1	0.6	-3.0	-2.5	-3.1	-3.7	-2.6	-2.9	-0.9	-1.2	-2.9	-2.9	-0.1	-2.7	-2.5	-2.7
Medication: Gliclazide	1.7	1.9	4.6	1.5	-2.1	-1.8	-0.1	-1.3	-1.5	-1.4	-0.7	-0.8	-1.4	-1.2	-1.2	1.1	-0.7	-2.0	-1.4	-1.2	-2.1	-0.5	0.4	-1.8	-0.7	-1.8
Pain type(s) experienced in last month: Hip pain	1.7	2.1	8.1	0.5	1.5	1.8	2.8	1.3	1.1	0.3	1.4	0.5	1.2	1.3	1.2	1.7	1.0	1.9	1.6	1.3	1.1	2.5	1.2	1.3	1.5	0.8
High cholesterol (Self-reported)	1.7	2.9	11.8	0.1	-2.7	-3.1	-1.8	-1.1	-0.4	-0.0	-0.3	-0.3	-0.6	-0.6	-1.1	-2.0	-3.1	-1.9	-2.6	-2.0	-1.4	-3.4	-1.0	-0.6	-0.8	-0.1
Irritable Bowel Disease (IBD)	1.6	3.7	9.7	1.5	-1.2	-1.5	-1.4	-2.3	-2.5	0.7	-1.4	-1.0	-2.6	-2.6	-2.3	0.0	-0.4	-1.9	-2.0	-1.3	-2.5	-1.5	0.5	-2.8	-3.1	-3.0
Relative age of first facial hair	1.6	3.3	7.8	-2.3	0.1	0.9	1.1	2.5	2.3	-0.3	1.9	-1.5	2.5	2.7	2.4	1.2	-0.5	1.8	1.9	0.3	2.0	1.6	-0.1	2.5	1.8	2.8
Financial difficulties in last 2 years	1.6	2.2	7.0	-1.0	2.3	1.7	0.4	1.1	1.7	-0.9	1.7	-0.7	1.6	0.8	1.4	0.3	1.1	0.9	0.4	2.5	1.8	1.5	1.2	1.8	2.6	1.3
Illnesses of father: High blood pressure	1.6	2.0	5.8	-1.8	0.7	0.9	1.6	1.5	1.7	0.6	1.5	-2.4	1.7	1.5	1.3	-0.4	-0.1	0.9	1.8	0.2	2.0	0.1	-0.2	1.7	1.8	2.0
Arm predicted mass (left)	1.6	7.9	32.7	5.7	-1.6	-0.6	0.0	-3.5	-4.0	0.7	-0.8	1.2	-3.8	-3.5	-3.6	-1.6	0.1	-1.6	-1.4	-3.2	-2.0	-2.4	1.4	-3.7	-3.6	-4.5
Alzheimer’s Disease (in mother)	1.5	1.8	4.7	-1.3	0.1	1.1	-0.2	1.6	1.8	0.9	2.2	-0.3	2.0	1.8	1.9	-0.6	0.3	1.2	-0.2	1.6	1.2	1.2	0.3	1.7	1.6	1.7
Age when periods started (menarche)	1.5	3.6	6.7	-2.0	1.4	2.2	2.1	2.1	2.5	0.9	2.2	-1.6	2.4	1.8	2.6	-0.4	0.2	2.0	1.8	0.4	1.8	2.1	1.8	2.3	1.9	2.2
Bilateral oophorectomy (both ovaries removed)	1.5	1.7	6.0	0.6	-1.6	-2.2	-0.6	-1.1	-1.0	-1.3	-1.4	-2.1	-0.9	-1.2	-1.4	-1.6	-1.8	-1.4	-0.5	0.2	-0.6	-2.5	-1.1	-0.8	-0.3	-0.3
Hayfever, allergic rhinitis or eczema	1.5	3.3	10.8	-1.8	1.5	1.4	-0.9	1.4	2.1	0.1	3.0	-1.5	2.1	2.2	2.1	0.7	0.6	1.6	1.0	3.3	2.9	1.0	0.4	2.4	1.1	2.1
Eye problems/disorders: Cataract	1.5	1.7	3.8	0.5	-1.3	-1.9	-1.5	-1.4	-1.4	-0.4	0.5	0.8	-1.5	-1.6	-1.4	-1.9	-0.3	-1.3	-0.9	-0.8	-1.6	-1.8	-1.5	-1.5	-1.4	-1.2
Lung FVC	1.4	7.1	12.5	-3.2	1.1	2.0	3.5	3.4	2.9	-2.5	2.7	-2.3	3.0	3.4	2.7	1.9	0.5	3.1	2.6	2.9	3.1	2.6	0.5	3.4	1.6	2.9
Diverticular disease/diverticulitis (self-reported)	1.4	1.6	5.0	-2.2	1.8	1.3	-0.5	1.2	1.1	1.3	1.1	0.8	1.2	1.3	1.6	0.4	1.5	0.7	1.5	0.8	1.4	1.7	0.5	1.3	1.2	1.2
Chronic bronchitis/emphysema (father)	1.4	1.6	5.2	0.7	-0.8	-0.6	0.8	-0.8	-1.1	-2.0	-1.2	-1.5	-1.2	-2.0	-1.6	-2.3	-0.3	-0.2	-1.1	0.7	-1.7	-0.2	-1.7	-1.6	0.1	-1.0
Heart attack	1.4	1.7	6.5	1.5	0.1	-0.8	0.4	-1.4	-1.9	0.2	-0.5	1.8	-1.8	-1.7	-1.7	-0.4	0.7	-0.1	0.6	0.3	-1.6	-1.2	0.4	-2.1	-1.5	-2.5
Ever highly irritable/argumentative for 2 days	1.4	1.6	5.9	-1.5	2.4	1.5	1.0	1.3	0.9	0.6	1.0	0.4	1.0	1.1	1.4	0.7	1.5	1.3	1.8	1.2	1.5	2.1	1.0	1.1	-0.1	0.9
Leg pain on walking	1.4	1.8	5.3	0.5	2.3	1.7	1.1	1.7	1.2	-0.1	1.2	0.2	1.4	1.2	1.6	0.6	1.9	2.1	1.8	0.5	1.0	1.6	0.8	1.1	1.1	1.0
Arm fat-free mass (left)	1.4	7.0	29.6	5.4	-1.4	-0.3	0.5	-3.1	-3.9	1.1	-0.6	1.3	-3.6	-3.1	-3.4	-1.8	0.2	-1.3	-1.0	-3.2	-1.8	-2.0	1.5	-3.5	-3.4	-4.3
Heart disease (siblings)	1.4	1.8	4.3	0.7	-1.1	-1.3	-0.7	-2.1	-1.3	-0.9	-0.8	-1.8	-1.6	-2.0	-1.7	-0.2	-1.3	-1.9	-0.8	-0.9	-1.2	-1.5	-1.9	-1.0	-1.0	-0.1
Ulcerative Colitis (UC)	1.3	2.4	7.8	1.4	-0.5	-0.8	-1.2	-2.0	-2.0	0.8	-0.9	-0.3	-2.2	-1.9	-1.6	0.4	-0.0	-1.4	-1.9	-1.2	-1.7	-1.1	0.3	-2.3	-2.8	-2.3
Crohns Disease (2012)	1.3	2.1	5.0	0.3	-2.0	-2.2	-0.8	-1.5	-1.3	-0.0	-1.6	-2.1	-1.3	-1.6	-1.7	0.0	-1.2	-2.2	-1.9	-0.6	-1.6	-1.6	0.1	-1.6	-1.3	-1.4
Fasting Glucose	1.3	1.6	4.8	0.4	-2.2	-1.9	-2.1	-0.9	-1.1	1.0	-0.8	0.2	-1.1	-1.0	-1.0	-0.5	-1.7	-1.7	-1.2	-1.2	-0.7	-1.9	0.1	-0.9	-1.7	-0.8
Ever had hysterectomy (womb removed)	1.3	1.5	10.0	-1.4	-0.9	-1.5	0.1	1.2	1.1	-1.3	-0.2	-3.2	1.2	1.0	0.7	-0.8	-1.8	0.2	0.2	1.0	0.6	-1.3	0.2	1.3	1.0	1.4
Alcohol usually taken with meals	1.3	2.1	8.5	2.1	-1.8	-2.0	0.2	-1.1	-1.4	-0.0	-2.1	-1.0	-1.5	-1.7	-1.4	0.5	-1.7	-1.4	-0.9	-0.1	-1.4	-2.9	0.2	-1.4	-1.4	-1.1
Qualifications: None of the above	1.3	2.7	6.9	1.0	-0.4	-1.9	-1.0	-2.1	-2.4	-0.9	-0.7	0.6	-2.2	-2.4	-1.9	-0.4	0.6	-1.7	-1.3	-0.5	-2.4	-0.9	-1.9	-2.6	-1.6	-2.4
Noisy workplace	1.3	1.6	4.9	1.5	-0.7	-2.2	-0.0	-1.3	-1.8	-0.7	-0.1	0.8	-1.7	-1.4	-1.9	-0.9	-0.5	-1.2	-0.6	-0.3	-2.0	-0.6	-0.4	-1.8	-1.2	-1.7
Mineral and other dietary supplements	1.3	1.7	5.7	-1.0	-0.4	-0.1	-0.1	2.2	1.8	1.3	0.7	-1.2	1.8	2.4	1.4	0.5	-1.2	0.9	0.8	0.7	1.2	0.0	2.0	1.8	1.5	1.2
Supplements: Calcium	1.3	1.4	3.1	0.9	-0.7	-1.1	1.0	-1.4	-1.4	-0.8	-0.0	-0.1	-1.3	-1.6	-1.4	0.6	-0.7	-1.3	-1.6	-1.6	-1.6	-1.8	-0.3	-1.5	-0.9	-1.2
Supplements: Zinc	1.2	1.3	9.6	-0.6	0.7	-0.5	-0.6	-0.9	0.5	-3.1	-0.0	-1.0	0.2	-1.2	-0.0	0.3	0.6	-0.0	-0.6	0.1	0.5	-0.1	-3.1	0.1	1.4	1.2
Leg fat-free mass (left)	1.2	6.4	20.3	2.5	3.4	4.5	2.9	1.8	1.0	2.8	1.9	2.4	1.3	1.8	2.0	-1.0	4.0	3.5	2.5	-0.6	3.1	3.2	3.3	1.4	0.7	0.0
Medication for cholesterol, blood pressure or diabetes	1.2	2.1	6.6	0.9	2.0	2.5	1.8	1.0	0.3	-1.7	1.3	-0.2	0.6	1.0	0.9	2.5	2.5	1.4	-0.6	0.4	1.0	2.6	1.6	0.5	0.2	-0.3
High blood pressure (siblings)	1.2	1.8	4.5	1.0	0.3	-1.6	-1.1	-1.9	-1.9	-0.4	-0.5	0.8	-1.8	-1.5	-1.8	-0.6	0.6	-1.2	-0.4	-0.7	-1.9	-1.5	-1.1	-2.1	-1.1	-2.1
Knee pain experienced in last month	1.2	1.9	8.4	0.1	2.9	2.0	-0.3	1.0	0.8	0.2	0.6	0.7	0.9	1.0	1.4	0.8	2.7	1.6	0.1	1.2	1.4	2.6	1.5	0.8	0.9	0.1
Asthma (self-reported)	1.2	2.5	6.4	1.1	-1.7	-1.5	-1.1	-1.5	-1.6	0.5	-1.8	-1.1	-1.5	-1.2	-1.6	-0.7	-2.5	-2.3	-2.0	0.6	-1.8	-2.5	0.6	-1.3	-2.0	-1.1
Deep venous thrombosis (DVT) (self-reported)	1.2	1.5	6.6	-2.6	1.5	0.9	-0.8	0.8	1.1	2.5	1.6	-0.1	1.1	0.8	1.2	-0.1	1.2	0.5	1.3	0.4	0.3	1.8	1.3	0.7	0.9	0.3
Verbal and Numeric Reasoning (VNR)	1.1	2.8	7.9	-2.8	-0.3	0.5	0.7	2.6	2.5	0.7	0.3	-0.4	2.5	2.8	2.2	-0.7	-0.6	1.4	0.6	0.3	1.1	0.3	1.6	2.4	2.4	1.9
Neuroticism (2016)	1.1	1.5	6.9	-0.9	-1.1	-1.8	-2.0	0.2	0.5	-0.1	-1.5	-2.3	0.5	-0.4	-0.2	-1.6	-2.6	-1.1	-0.3	-1.0	-0.0	-1.9	-0.2	0.7	0.7	1.2
Chronotype (morning person)	1.1	2.6	12.0	3.5	-0.5	-0.7	-0.6	-1.7	-2.5	0.0	-0.4	1.4	-2.4	-1.6	-2.2	1.0	0.4	-0.6	-0.5	-0.6	-1.4	-0.7	-1.1	-2.2	-2.2	-2.3
Medication: Metformin	1.1	1.6	8.1	0.1	-1.5	-2.4	0.1	-1.0	-0.6	0.3	-0.8	-1.3	-0.8	-0.8	-1.2	-1.3	-2.8	-2.2	-0.4	-0.4	-2.0	-1.1	0.1	-0.9	0.8	-0.5
Leg predicted mass (left)	1.1	5.8	18.7	2.6	3.3	4.3	2.8	1.6	0.8	2.9	1.8	2.4	1.1	1.6	1.8	-1.0	3.9	3.4	2.3	-0.7	2.9	3.0	3.3	1.2	0.5	-0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.6	7.2	-1.9	0.3	0.9	-1.6	0.2	1.8	-0.4	-0.4	-1.1	1.4	0.3	1.3	-0.8	-0.7	-0.7	0.4	0.5	1.7	1.0	-0.9	1.9	2.2	2.7
Eye problems/disorders: None of the above	1.1	1.3	6.4	-0.5	1.3	2.5	0.8	1.0	1.0	0.5	-1.3	0.5	1.1	1.5	1.4	1.1	1.6	0.8	0.7	-0.5	0.6	1.9	1.0	0.8	0.7	0.6
Had major operations	1.1	1.3	5.4	0.4	-1.0	-0.3	-1.8	-2.3	-0.8	-0.9	-0.6	0.4	-1.1	-2.2	-1.3	-0.9	-0.0	-1.4	-0.1	-0.5	-0.6	-0.9	-2.0	-1.0	-0.7	-0.4
Supplements: Fish oil (including cod liver oil)	1.1	1.5	5.7	0.3	0.6	0.0	0.2	-1.9	-1.7	-1.3	-0.4	0.5	-1.7	-2.3	-1.4	-0.1	1.3	-0.7	-0.4	-0.7	-0.9	0.8	-2.4	-1.7	-1.3	-1.0
Ever had prostate specific antigen (PSA) test	1.1	1.2	5.3	0.4	-1.6	-2.0	-1.4	-0.8	-0.2	0.8	-1.1	-0.8	-0.3	-0.6	-0.9	-1.5	-2.3	-1.0	-0.6	-0.4	0.3	-2.3	0.3	0.2	-0.7	0.4
Medication: Omeprazole (e.g. Zanprol)	1.1	1.3	9.1	-1.9	0.0	0.1	0.6	1.0	1.4	-0.6	3.0	-1.2	1.3	0.3	0.8	0.2	-0.6	1.0	1.0	0.7	1.1	-0.2	0.4	1.3	1.4	1.2
Heart attack/myocardial infarction (self-reported)	1.1	1.4	5.2	1.4	0.1	-0.7	0.3	-1.1	-1.6	0.3	-0.5	1.8	-1.6	-1.5	-1.4	-0.4	0.7	-0.1	0.7	0.4	-1.4	-0.9	0.6	-1.9	-1.2	-2.3
Ovarian Cancer	1.0	1.3	5.5	0.7	-0.1	0.1	-0.0	-1.5	-1.4	-1.0	0.4	-0.5	-1.5	-1.5	-1.8	-1.3	0.5	-0.2	-0.8	-2.4	-0.3	-0.6	-1.8	-1.2	-1.3	-0.6
Blood Platelet Count	1.0	12.1	25.3	3.6	-1.8	-3.6	-2.5	-5.0	-4.6	-1.8	-1.1	-0.0	-4.7	-3.9	-4.6	-1.5	-1.7	-4.8	-2.9	-2.1	-4.9	-3.0	-2.5	-4.8	-4.0	-4.0
Height	1.0	19.7	91.6	4.9	-2.8	-0.1	-2.7	-3.9	-5.3	9.6	-2.4	3.7	-5.0	-4.9	-4.6	-2.3	-1.4	-1.3	0.3	-7.4	-3.3	-2.6	2.9	-5.2	-5.9	-6.1
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.3	3.0	1.2	0.6	0.1	-1.7	-1.5	-1.1	-1.1	-1.3	0.8	-1.3	-1.7	-1.3	-1.4	-0.0	-1.2	-1.7	-1.1	-0.3	-0.4	-1.3	-0.9	-1.1	-0.2
Asthma	1.0	2.1	6.0	0.8	-1.7	-1.3	-0.8	-1.4	-1.4	0.3	-1.7	-1.0	-1.4	-1.1	-1.4	-0.6	-2.5	-2.2	-1.8	0.5	-1.7	-2.4	0.7	-1.1	-1.7	-1.0
Lung cancer (father)	1.0	1.2	5.7	0.1	-0.4	-0.4	-1.5	-1.3	-1.1	0.2	-0.5	2.4	-1.2	-1.1	-0.7	-1.7	-0.8	-1.6	-0.7	-0.9	-1.0	-0.6	0.5	-1.0	-1.0	-1.0
Medication for pain relief, constipation, heartburn	1.0	1.8	4.5	1.7	-1.1	-0.5	-0.1	-1.2	-1.7	-0.4	-0.8	0.7	-1.4	-0.6	-1.0	-0.2	0.2	-1.9	-2.0	-2.1	-1.8	0.3	1.2	-1.6	-1.8	-2.1
Medication: Omeprazole	1.0	1.2	10.1	-1.7	0.2	0.1	0.3	0.9	1.4	0.2	3.2	-0.6	1.3	0.3	1.0	0.7	-0.1	0.9	1.3	0.9	1.1	0.0	0.4	1.3	1.0	1.2
Medication: Seretide 50 evohaler	1.0	1.2	5.2	2.1	0.3	-0.7	0.6	-0.6	-0.6	-1.6	-0.8	-1.0	-0.5	-0.9	-0.6	1.0	-0.4	-0.6	-1.8	2.3	-0.2	-1.0	-1.6	-0.7	0.9	-0.1
Comparative height size at age 10	1.0	5.6	32.0	3.1	-0.9	-0.7	-0.9	-1.8	-3.0	5.7	-0.8	2.2	-2.6	-2.5	-2.5	-0.9	0.2	-0.2	0.2	-2.8	-1.5	-1.5	1.3	-3.0	-3.5	-3.6
Wears glasses or contact lenses	1.0	1.1	6.0	0.7	-1.2	-0.8	-2.5	-1.0	-0.5	0.7	0.1	0.3	-0.6	-0.8	-0.6	-1.4	-1.3	-1.1	-1.3	-0.6	0.2	-1.7	-1.8	-0.3	-0.6	0.3
Medication: Paracetamol	1.0	1.6	4.4	-1.2	1.5	0.7	1.0	1.3	1.4	-0.8	0.3	-0.5	1.4	0.9	1.0	0.3	0.3	1.5	0.2	2.1	1.9	0.7	-1.4	1.5	1.9	2.0
Schizophrenia vs Biploar Disorder	0.9	1.1	3.3	1.8	-0.3	-0.6	1.0	-1.5	-1.4	0.3	-0.8	-0.7	-1.5	-1.3	-1.4	1.4	-0.6	-1.2	-0.1	-0.4	-0.8	-1.1	-0.8	-1.2	-1.2	-0.6
Major Depression (MDD)	0.9	1.1	3.1	-1.8	0.6	1.4	0.4	1.2	1.7	-0.4	0.7	-0.9	1.1	0.7	0.9	0.7	0.3	0.9	1.0	-0.3	0.9	0.7	-0.8	1.4	1.6	1.8
Waist circumference	0.9	3.3	11.6	3.4	-0.1	-0.6	-0.1	-2.0	-2.7	1.1	0.1	-0.1	-2.5	-1.7	-2.5	-3.2	-0.5	-0.8	-0.0	-1.6	-0.8	-2.0	0.5	-2.1	-2.6	-2.6
Nervous feelings	0.9	1.7	3.9	-0.6	1.5	0.2	-0.4	1.9	1.5	0.8	0.4	-1.0	1.5	1.8	1.5	0.8	-0.0	0.9	1.2	2.0	1.8	1.0	0.8	1.9	1.3	2.0
Pulse rate	0.9	1.5	3.5	0.5	-0.2	-1.4	-1.2	-1.4	-1.2	0.8	-0.7	0.1	-1.3	-1.4	-1.3	-1.6	-1.5	-1.7	-1.9	-0.6	-1.0	-1.8	-1.2	-1.2	-1.1	-0.8
Medication: Paracetamol	0.9	1.5	4.8	-1.6	0.9	0.5	0.4	1.0	1.5	-1.1	0.2	-0.9	1.4	0.9	0.8	0.2	0.0	1.2	0.5	1.7	2.0	0.2	-1.7	1.6	1.9	2.2
Glaucoma (self-reported)	0.9	1.0	5.3	-0.2	0.1	0.3	1.4	0.7	0.5	-0.0	2.3	-1.0	0.6	1.3	0.2	-1.0	-1.1	1.1	1.7	1.5	0.4	1.6	0.4	0.6	0.1	0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	7.1	-0.4	-1.0	-1.1	-2.6	-0.8	-0.1	0.7	-0.5	-0.4	-0.3	-0.3	-0.5	-2.7	-1.3	-1.2	-0.9	-1.7	0.3	-1.0	-0.2	0.0	-0.7	0.1
Health satisfaction	0.9	1.2	6.2	-0.4	1.5	0.8	0.5	1.0	0.5	0.6	1.7	1.7	0.7	0.7	1.1	-1.3	0.8	0.8	2.5	-0.3	0.9	1.5	0.8	1.0	0.2	0.8
Whole body fat-free mass	0.9	5.1	26.8	5.2	-0.7	0.1	0.6	-2.3	-3.0	1.9	-0.4	1.5	-2.8	-2.3	-2.5	-1.9	0.8	-0.5	-0.4	-3.3	-1.1	-1.2	2.1	-2.7	-2.5	-3.7
Medication: Aspirin	0.9	1.2	5.3	0.6	-0.6	-1.4	-1.2	-1.3	-0.5	0.6	-0.4	0.4	-0.9	-1.6	-1.1	-1.5	-1.9	-0.4	0.1	-0.1	-1.0	-2.3	-1.8	-0.8	-0.5	-0.2
Illnesses of father: None of the above (group 1)	0.9	1.2	5.5	-0.1	1.1	0.3	-1.1	1.3	0.8	2.2	0.3	1.4	1.0	1.6	1.4	1.0	0.9	0.6	-0.3	0.6	0.3	1.0	2.3	0.6	-0.0	-0.2
Whole body water mass	0.9	5.2	27.4	5.2	-0.8	0.1	0.6	-2.4	-3.1	1.8	-0.5	1.5	-2.8	-2.4	-2.5	-1.9	0.8	-0.5	-0.6	-3.3	-1.1	-1.3	2.0	-2.8	-2.6	-3.8
Guilty feelings	0.9	1.4	10.6	-0.7	-0.3	0.1	-2.0	0.1	1.1	-1.8	0.2	-3.2	0.9	0.1	0.2	0.5	-0.9	-0.6	-1.5	-0.1	1.3	-0.9	-0.0	1.2	1.3	1.5
Alcohol drinker status: Never	0.9	1.1	6.2	0.3	2.5	0.9	0.8	0.1	-0.1	-1.1	1.6	0.1	0.1	0.3	0.3	0.9	2.5	1.2	1.1	0.6	0.5	1.4	-0.7	0.1	0.3	0.2
Bipolar Disorder (2018)	0.8	1.3	3.8	-1.8	0.5	0.3	-1.4	0.4	1.3	0.0	-0.5	-1.6	1.2	0.7	0.9	-1.5	-1.2	-0.6	-1.1	1.0	1.1	-0.5	-0.4	1.6	1.9	1.8
Blood Eosinophil Count	0.8	6.4	14.7	3.7	-0.9	-2.4	-1.7	-2.9	-3.7	3.0	0.8	-0.1	-3.5	-2.4	-3.5	-1.0	-0.7	-2.6	-0.0	-1.3	-2.8	-2.2	0.5	-3.7	-3.6	-3.8
Diabetes (father)	0.8	1.0	6.9	0.8	-0.4	0.2	0.5	-1.5	-1.1	-0.7	0.1	1.0	-1.3	-1.5	-1.2	0.9	-0.0	-1.0	0.1	-0.4	-0.4	0.3	-2.6	-1.1	-0.5	-0.3
Pack years adult smoking proportion	0.8	1.2	3.3	-1.6	1.4	1.5	1.1	1.0	1.0	-1.2	-0.5	0.1	1.0	0.6	0.8	1.7	1.5	1.6	1.8	-0.3	1.2	0.9	0.2	0.9	0.6	0.5
Townsend deprivation index at recruitment	0.8	1.2	4.1	-1.5	2.0	1.4	-0.1	0.9	0.8	0.3	0.9	0.5	1.2	0.1	1.2	0.4	2.0	1.3	-0.2	0.8	1.1	1.4	-0.4	0.6	1.5	1.0
Allergy	0.8	1.9	12.2	1.3	-1.4	-0.9	1.5	-0.8	-1.3	-1.1	-2.2	1.6	-1.3	-1.5	-1.3	0.1	-0.0	-1.0	-0.0	-3.5	-1.6	-0.3	-1.5	-1.5	-0.2	-0.9
Medication: Cholesterol lowering	0.8	1.3	5.2	-0.3	-1.8	-2.3	-1.5	-0.5	-0.1	1.3	-0.9	-0.6	-0.3	-0.5	-0.8	-1.2	-2.2	-1.0	-0.4	-0.1	-0.9	-2.3	-0.6	-0.3	0.1	0.1
Depression (self-reported)	0.8	1.0	4.5	-0.9	-1.2	-0.3	-1.6	-1.0	0.4	0.9	-0.3	-0.4	0.2	-0.7	-0.2	-2.1	-1.5	-1.6	-0.3	-1.6	-0.0	-0.3	-1.2	0.2	0.7	0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.4	4.6	-1.9	-0.6	1.7	1.4	1.7	1.8	1.7	1.2	-2.1	1.8	2.0	1.2	-0.7	-1.4	1.6	1.9	-0.0	2.0	0.8	1.5	2.1	0.8	1.6
Standing height	0.8	8.1	44.1	3.6	-1.9	-0.6	-1.5	-2.6	-3.1	6.6	-2.0	1.0	-3.0	-3.0	-2.9	-0.9	-1.2	-1.1	-0.0	-5.0	-1.8	-2.3	2.4	-3.0	-3.4	-3.5
Peak expiratory flow (PEF)	0.8	2.0	14.6	0.8	-2.2	-0.5	0.5	-0.5	-0.1	1.2	-1.8	-2.2	-0.2	-0.4	-0.8	-1.7	-3.8	-1.4	-0.9	-1.0	-0.1	-1.9	1.8	0.1	-0.2	-0.0
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	3.9	0.2	-0.4	0.9	1.6	0.9	1.3	-1.7	0.8	-0.2	1.4	0.9	0.7	0.6	-1.4	1.0	-0.7	1.7	1.6	-0.1	0.1	1.7	1.2	2.0
Blood clot in the leg (DVT)	0.8	1.0	5.3	-2.3	1.2	0.7	-0.9	0.5	0.8	2.1	2.0	-0.1	0.8	0.4	0.8	-0.0	0.9	0.2	0.7	0.3	0.1	1.4	0.9	0.4	0.7	0.1
Leg fat-free mass (right)	0.8	4.4	15.0	3.1	2.6	3.9	2.6	1.0	0.2	2.3	1.6	2.2	0.6	1.2	1.2	-0.8	3.5	2.8	2.0	-0.7	2.4	2.6	2.8	0.6	0.0	-0.6
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	6.7	-1.1	-1.6	-0.9	-0.8	-0.1	0.0	-0.8	-2.1	0.5	0.1	-0.4	-0.1	-2.5	-2.6	-1.3	0.2	-1.6	-0.5	-0.6	-0.8	0.2	1.2	0.7
Leg predicted mass (right)	0.8	4.4	15.2	3.1	2.7	3.9	2.6	1.0	0.2	2.3	1.5	2.1	0.6	1.2	1.2	-0.7	3.6	2.8	2.0	-0.7	2.3	2.6	2.8	0.6	0.0	-0.6
Rheumatoid Arthritis	0.7	1.0	3.3	-0.4	0.8	0.4	1.3	1.2	1.1	-0.3	1.8	-1.5	1.1	1.2	0.6	-0.7	0.3	1.2	-0.1	1.6	0.7	0.6	0.3	0.9	0.9	0.8
Systolic Blood Pressure	0.7	3.6	13.0	1.5	-2.0	-3.6	0.4	-2.0	-2.1	-0.1	0.4	-0.3	-2.1	-1.4	-2.0	0.3	-2.5	-1.6	-0.5	-0.5	-3.1	-3.1	0.2	-2.3	-2.1	-2.3
Lung FEV1/FVC ratio	0.7	3.6	16.2	-2.8	-3.1	-0.8	-1.4	0.9	2.0	1.2	-0.2	-0.7	1.7	1.1	1.0	-2.4	-4.0	-1.7	2.9	-1.5	0.1	0.2	2.5	1.9	1.9	1.8
Other serious medical condition/disability diagnosed by doctor	0.7	1.0	3.6	0.1	0.3	-0.9	0.0	0.8	1.1	-0.7	1.4	-0.9	0.9	0.4	0.5	-1.8	-1.2	0.5	0.0	-0.1	1.2	-0.1	-0.6	1.3	1.7	1.9
Relative age voice broke	0.7	1.1	4.8	-1.9	0.0	0.0	-0.5	1.1	1.5	0.2	0.6	-0.7	1.4	0.8	1.3	0.1	-0.5	0.8	-0.3	-0.3	1.1	0.8	-0.4	1.6	1.4	2.2
Medication: Ramipril	0.7	1.0	3.8	0.8	-0.3	-1.0	0.6	-0.4	-0.7	-0.4	-0.3	2.0	-0.8	-0.5	-1.1	-1.9	-1.8	-0.0	0.7	1.4	-1.1	-1.3	0.1	-0.5	-0.3	-0.7
Forced expiratory volume in 1-second (FEV1)	0.7	2.2	4.3	-1.8	-0.4	1.7	0.9	1.9	1.8	2.1	0.5	-1.4	1.7	1.9	1.4	-1.6	-1.1	1.3	1.4	-0.5	1.9	0.7	1.7	2.0	0.7	1.5
Medication: Lansoprazole	0.7	0.8	5.6	0.1	-0.3	-1.2	-1.0	-0.2	-0.0	1.1	0.6	-0.4	-0.2	-0.3	-0.9	-2.4	-1.8	-0.4	-1.2	-0.9	-0.3	-0.7	-1.2	-0.1	0.9	0.3
Pulse wave Arterial Stiffness index	0.7	0.9	3.3	1.0	-1.1	-1.0	-1.0	-0.5	-0.6	0.4	-0.7	-0.8	-0.6	-0.5	-0.6	-0.1	-1.8	-0.8	-1.4	-0.0	-0.1	-1.8	1.5	-0.1	-1.2	-0.4
Breastfed as a baby	0.7	0.8	2.3	0.1	-0.2	1.5	1.1	1.1	0.8	-0.4	1.3	1.5	0.9	1.1	1.3	0.8	0.8	1.2	0.3	-0.3	0.5	1.0	0.9	0.7	0.3	0.2
Tense / ‘highly strung’	0.7	1.1	5.8	-0.7	-0.5	-1.5	-2.4	-0.9	-0.3	0.2	-1.2	-1.9	-0.5	-1.0	-0.9	0.3	-1.3	-1.1	-1.0	-0.3	-0.1	-1.4	-1.6	-0.0	0.0	0.7
Birth weight	0.7	1.6	12.4	1.6	-0.8	-0.7	-0.1	-1.9	-1.1	0.3	-1.1	1.2	-1.2	-1.7	-1.2	-0.8	-0.7	-1.2	0.6	-3.5	-0.6	-1.1	-0.7	-1.1	-0.7	-0.6
Emphysema/chronic bronchitis	0.7	0.8	2.8	-1.7	1.3	0.4	0.2	1.0	1.0	-0.9	0.6	-1.4	1.0	0.8	0.8	-0.5	0.3	0.9	0.1	1.2	0.4	0.3	0.8	0.9	1.1	0.7
Medication: Aspirin	0.7	0.9	4.0	0.3	-0.4	-1.2	-1.1	-1.2	-0.3	0.8	-0.4	0.8	-0.6	-1.4	-0.8	-1.3	-1.5	-0.3	0.6	-0.2	-0.8	-2.0	-1.9	-0.6	-0.3	-0.0
Supplements: Vitamin C	0.7	0.9	5.3	-0.7	-0.6	-1.2	-0.9	-1.1	-0.8	-1.6	-0.6	0.2	-0.8	-1.3	-0.9	-0.3	0.5	-1.0	-0.3	-1.0	-0.3	-0.6	-2.3	-0.8	-0.5	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.4	6.7	0.5	-0.1	0.3	-0.2	-1.0	-1.3	2.5	-0.4	0.6	-1.1	-0.8	-1.0	-1.9	1.0	-0.4	1.7	-2.6	-0.9	0.1	-0.0	-1.4	-0.6	-1.4
Back pain experienced in last month	0.7	1.0	3.3	0.4	1.8	1.3	0.9	0.3	0.6	-0.4	1.0	1.6	0.5	0.3	0.9	-0.5	1.5	0.8	-0.2	1.7	1.3	1.5	-0.3	0.8	0.8	0.8
Osteoarthritis (self-reported)	0.7	0.9	4.2	0.0	1.4	0.9	-0.5	-0.9	-0.6	1.0	1.0	2.1	-0.6	-0.2	0.0	0.9	1.7	-0.2	1.5	-0.9	-0.5	1.0	0.1	-0.6	-0.8	-1.0
Ever taken oral contraceptive pill	0.7	0.8	3.4	0.1	-1.8	-1.1	-0.5	0.4	0.5	-1.5	-1.3	-0.4	0.4	0.8	0.3	-0.1	-1.7	-0.8	-1.1	-0.7	-0.7	-1.1	0.6	0.4	0.1	0.5
Hearing aid user	0.7	0.8	2.8	0.5	-0.7	-0.6	-0.8	-1.1	-1.1	-0.8	-0.6	-0.3	-1.1	-0.3	-0.9	0.1	-0.1	-1.2	-1.5	0.3	-1.0	-0.9	0.6	-0.8	-1.7	-1.1
Financial situation satisfaction	0.7	0.9	3.5	-0.3	1.2	1.3	1.0	0.4	0.6	-0.2	0.8	1.9	0.6	0.6	0.8	0.9	0.6	0.7	0.7	1.4	0.5	1.9	0.4	0.8	0.8	0.8
Commuting to job workplace: Public transport	0.7	0.9	4.7	-0.1	0.6	0.6	0.9	1.3	0.8	1.0	0.6	-0.5	1.1	1.3	0.7	-0.5	-0.1	1.4	2.2	0.4	1.0	0.4	1.3	0.9	0.4	0.3
Unable to work because of sickness or disability	0.7	0.9	4.0	-0.8	-0.7	-0.2	-1.1	-0.9	-0.1	1.7	-0.3	0.1	-0.2	-0.4	-0.6	-1.8	-1.3	-1.2	0.9	-2.0	0.2	-1.0	-0.7	0.2	0.1	0.5
Worry (Nagel 2018)	0.6	1.2	7.0	-0.9	-0.4	-1.3	-2.6	-0.3	0.5	0.6	-1.3	-2.0	0.2	-0.4	-0.3	-0.7	-1.5	-0.9	-0.8	0.0	0.9	-1.7	-1.0	0.9	0.5	1.4
Respiratory disease	0.6	1.3	3.8	0.3	-0.5	-0.8	-1.1	-0.7	-1.1	1.9	-1.3	-1.2	-0.9	-0.4	-0.7	-0.9	-1.0	-1.4	-2.0	0.8	-1.1	-1.9	1.3	-0.8	-1.6	-0.9
Ever used hormone-replacement therapy (HRT)	0.6	0.7	2.2	1.1	-1.5	-0.6	-0.0	-0.3	-0.8	-1.2	0.1	-0.7	-0.8	-0.5	-0.7	-0.6	-1.2	-0.2	-0.6	-0.5	-1.0	-1.0	1.3	-0.6	-1.2	-1.1
Medication for hormone replacement therapy	0.6	0.7	3.1	-0.1	-1.3	-0.8	1.6	0.1	-0.1	-1.1	0.6	-1.5	-0.2	-0.6	-0.7	-0.9	-1.8	-0.3	0.4	0.4	-0.3	-0.6	0.9	-0.0	-0.1	-0.3
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	5.1	-0.8	-0.2	-0.8	-1.3	-0.5	0.6	0.3	-0.5	-2.3	0.3	-0.4	-0.3	-0.0	-2.0	-1.2	-0.8	-0.7	0.4	-1.5	-0.9	0.7	1.1	1.4
Had other major operations	0.6	0.7	3.8	0.3	-0.1	-0.1	-0.8	-0.1	0.7	-1.5	-0.2	1.2	0.4	-0.7	0.2	-1.4	-0.3	-0.3	-0.5	-0.2	1.2	-0.0	-0.7	0.7	2.0	1.0
Neuroticism score	0.6	1.3	7.1	0.9	0.2	-0.3	-2.7	-1.6	-0.9	0.1	-1.0	-1.4	-1.1	-1.2	-1.2	0.5	-0.6	-1.8	-1.2	-0.7	-0.5	-1.4	-1.3	-0.6	-0.8	-0.1
Worrier / anxious feelings	0.6	1.1	4.3	-1.2	1.4	0.2	-0.9	0.5	1.6	0.8	0.2	-0.2	1.5	1.0	1.2	0.0	-0.4	0.0	0.8	0.4	1.5	-0.0	0.2	1.9	1.5	2.1
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	3.1	-1.4	0.3	0.2	-0.3	0.6	1.4	-1.8	0.2	-1.2	1.2	0.4	0.9	0.0	-0.3	-0.1	0.2	0.0	1.6	-0.4	-0.2	1.6	1.4	1.8
Mouth/teeth dental problems: Dentures	0.6	1.0	4.4	1.7	1.1	-0.3	1.4	-0.6	-0.7	-0.7	-0.7	0.8	-0.7	-1.3	-0.4	2.1	1.2	-0.0	-1.0	0.4	-1.2	-0.0	-1.0	-1.3	0.7	-0.9
Hair/balding pattern: Pattern 4	0.6	1.4	3.5	-0.5	1.1	1.3	1.0	1.3	1.3	1.0	1.0	0.2	1.4	1.8	1.2	-0.3	-0.3	1.4	0.1	1.6	1.9	0.3	1.1	1.7	-0.1	1.8
Mouth/teeth dental problems: Loose teeth	0.6	0.8	5.6	1.2	0.0	0.3	0.1	-0.4	-0.7	-1.0	-1.4	0.1	-0.6	-1.3	-0.5	0.5	0.3	-0.6	-2.4	0.3	-1.1	0.7	0.6	-1.0	-0.3	-0.9
Migraine (self-reported)	0.6	0.8	2.7	-0.5	0.3	-0.3	1.1	1.1	1.1	-0.6	0.6	-1.5	0.9	1.1	0.6	-0.3	-1.1	0.3	0.2	0.8	0.4	-0.6	0.2	1.1	1.6	1.2
Heart disease (mother)	0.6	0.7	5.4	-0.5	-0.2	-0.3	-1.1	-0.8	-0.2	-0.3	-2.3	0.7	-0.4	-0.5	0.0	-0.7	-0.3	-1.0	-0.9	-0.9	-0.1	-1.8	-1.0	-0.0	-0.3	0.5
Alcohol intake frequency.	0.6	1.4	10.4	-0.3	3.2	-0.0	-1.0	-0.3	-0.4	0.5	0.7	0.1	-0.4	-0.6	-0.3	-0.4	2.8	0.5	0.7	0.3	-0.2	1.3	-2.4	-0.6	1.2	0.1
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	3.7	-1.3	-1.2	-0.3	-0.4	-0.4	0.2	-1.9	-1.6	-0.8	0.0	-0.7	-0.3	0.5	-0.6	-0.9	-0.8	-0.6	0.0	-0.8	-0.9	0.2	0.6	0.6
Average weekly red wine intake	0.6	0.9	3.9	1.1	-1.9	-0.4	1.8	0.6	0.4	0.5	-0.5	-0.3	0.4	1.0	0.0	0.8	-1.7	-0.1	-0.6	0.6	-0.3	-1.0	2.0	0.4	-0.5	-0.2
Long-standing illness, disability or infirmity	0.6	1.0	2.3	1.5	-0.3	-1.2	-0.3	-1.4	-1.2	0.5	1.0	1.2	-1.3	-1.1	-1.1	-0.8	-0.9	-1.2	-0.9	0.1	-0.7	-1.4	0.0	-0.8	-1.2	-0.5
Basal metabolic rate	0.6	3.1	17.3	4.2	1.0	1.9	1.3	-0.9	-1.7	2.4	0.4	1.8	-1.4	-0.9	-0.9	-1.7	2.0	0.9	0.6	-2.1	0.5	0.4	2.6	-1.3	-1.6	-2.5
Average weekly beer plus cider intake	0.6	0.9	3.5	-0.9	1.9	1.6	0.0	0.5	0.4	0.1	0.2	1.7	0.4	0.5	0.7	-0.7	1.7	0.6	1.1	-1.1	0.4	1.7	0.1	0.2	1.0	-0.1
Risk taking	0.6	0.9	2.9	1.3	-0.7	-0.9	-0.4	-1.0	-0.8	-0.9	0.2	-0.4	-1.0	-0.8	-1.1	-0.4	-0.3	-1.1	-1.3	-0.5	-1.2	-0.7	1.4	-1.2	-0.5	-1.7
Diastolic blood pressure, automated reading	0.6	2.0	6.4	-1.6	2.5	1.3	1.6	1.0	1.0	0.4	0.9	0.2	1.0	1.2	1.8	-0.9	1.8	1.1	2.1	2.4	0.5	1.5	1.9	0.9	0.6	0.5
Commuting to job workplace: Cycle	0.6	0.8	4.2	-0.0	-2.0	-1.3	1.5	1.1	0.5	0.2	-0.6	0.3	0.7	1.1	0.7	0.0	-1.6	0.2	-0.2	-0.3	0.2	-1.2	0.9	0.4	0.0	0.6
Cardiovascular Disease	0.5	1.8	10.2	0.2	-1.2	-2.1	-0.4	-1.6	-0.7	-0.5	-0.5	-1.1	-1.0	-0.8	-1.2	-2.0	-2.3	-1.9	-1.4	-0.7	-1.0	-3.2	-0.9	-0.4	-0.3	0.1
Number of treatments/medications taken	0.5	1.0	4.2	0.0	-0.2	-1.5	-1.3	-1.0	-0.2	0.9	-0.2	1.1	-0.4	-0.6	-0.2	-1.9	-1.4	-1.4	-1.2	0.8	-0.1	-2.0	-0.7	-0.0	-0.1	0.5
Average weekly spirits intake	0.5	0.6	5.0	1.5	0.5	0.1	0.6	-0.7	-0.7	-0.3	-0.3	0.7	-0.7	-0.3	-0.5	2.2	0.8	0.5	0.0	-0.1	0.3	-0.2	-0.3	-0.6	-1.0	-0.9
Systolic blood pressure, automated reading	0.5	1.4	6.8	1.4	0.2	-1.1	0.2	-1.4	-1.5	-0.3	0.7	0.7	-1.6	-0.7	-0.9	0.0	0.2	-0.7	-0.3	0.6	-1.5	-1.3	1.1	-1.6	-2.6	-2.3
Impedance of leg (right)	0.5	2.2	17.0	-4.1	-0.0	-0.9	-2.7	0.8	1.3	3.0	-1.1	-1.3	1.1	0.3	0.7	0.7	-1.9	-0.4	1.0	0.2	-0.1	-0.6	-0.2	0.8	1.0	1.4
Average weekly fortified wine intake	0.5	0.6	3.4	-0.9	-0.4	-0.0	-1.3	-0.2	0.3	-1.4	-0.1	-1.2	0.2	-0.6	-0.2	1.8	0.2	0.2	1.1	-1.0	0.4	-0.6	-0.6	0.2	-0.3	0.4
Maternal smoking around birth	0.5	0.7	6.1	-0.5	-0.3	0.1	-0.8	0.4	-0.0	-1.1	-1.3	-2.5	0.1	-0.4	0.2	-0.2	-0.3	-0.3	-1.4	1.2	-0.9	0.3	1.4	-0.1	0.2	-0.2
Supplements: Glucosamine	0.5	0.6	3.7	0.4	0.2	0.2	0.1	-0.8	-0.6	-1.9	-0.8	0.6	-0.8	-0.6	-0.3	0.6	0.9	-0.3	-0.9	-1.2	-1.0	0.6	-0.6	-0.8	-0.8	-0.8
Medication: Levothyroxine sodium	0.5	0.8	2.7	0.4	0.5	0.5	1.6	0.8	0.7	-0.6	1.3	-1.4	0.9	0.7	0.8	0.7	0.4	1.4	0.2	0.4	0.6	-0.1	1.6	0.9	1.6	0.2
Hair/balding pattern: Pattern 2	0.5	0.7	4.0	-0.3	-0.5	-0.5	-0.6	0.1	0.2	-1.2	-2.0	-1.0	0.2	-0.5	-0.2	-1.6	-1.5	-0.5	-0.8	-0.3	0.1	-0.9	-0.2	0.2	1.1	0.6
Had menopause	0.5	0.7	3.9	1.1	-0.4	-0.2	-0.5	-0.6	-0.8	-1.5	-0.5	0.6	-0.8	-1.0	-0.5	0.3	-0.0	-0.6	-2.0	0.4	-0.3	-1.0	-0.6	-0.7	-1.3	-0.6
Hair/balding pattern: Pattern 3	0.5	0.8	5.9	-0.3	1.2	0.6	0.8	0.5	0.4	0.4	0.5	2.4	0.4	0.7	0.8	0.3	2.0	0.6	0.2	0.6	0.0	1.2	0.2	0.1	0.7	-0.1
Pulse wave reflection index	0.5	0.6	4.5	-0.2	0.2	0.5	-0.5	0.3	0.4	-1.1	-0.1	-2.1	0.4	0.6	0.5	0.1	0.5	0.1	-0.9	1.2	0.6	0.4	1.9	0.6	-0.3	0.2
Exposure to tobacco smoke outside home	0.5	0.7	2.0	-0.2	1.4	0.3	-0.3	0.5	0.8	-0.8	0.5	0.3	0.8	0.4	0.4	-0.2	0.2	0.7	-0.4	1.3	1.3	1.0	-0.9	1.0	1.4	1.3
Comparative body size at age 10	0.5	1.5	4.9	1.1	1.0	1.3	2.2	1.3	1.1	-2.0	0.4	0.5	1.0	1.4	0.9	-0.2	1.3	1.9	1.1	0.4	1.3	1.6	-0.9	1.1	1.3	0.9
Pulse wave peak to peak time	0.5	0.6	2.5	-0.8	0.8	0.9	0.8	0.4	0.4	0.3	0.4	1.1	0.5	0.3	0.4	0.1	1.5	0.7	1.4	-0.4	-0.0	1.6	-1.2	0.0	1.0	0.2
Age at last live birth	0.5	0.7	3.1	-0.9	-0.3	1.1	-0.9	0.2	0.7	1.1	0.5	0.4	0.5	0.8	0.7	0.7	1.0	0.3	1.1	1.2	0.9	0.2	1.8	0.6	-0.1	0.0
Hypertension (Self-reported)	0.5	1.3	6.2	-0.9	-0.5	-2.3	-0.2	-1.3	-0.6	-0.9	-0.9	-0.0	-0.8	-0.9	-0.8	-2.2	-1.5	-1.6	-0.1	0.5	-0.8	-2.5	-1.1	-0.4	0.4	0.0
Breast cancer (self-reported)	0.5	0.6	3.3	-0.6	-0.4	-0.5	0.5	0.6	0.3	1.0	0.5	-0.3	0.3	0.1	-0.3	-0.7	-1.8	-0.3	-0.5	1.2	0.8	-1.3	0.8	0.8	0.2	0.8
Eye problems/disorders: Glaucoma	0.5	0.6	2.3	0.4	-0.7	-0.0	0.7	0.4	0.5	-0.6	1.1	-0.1	0.5	0.8	0.0	-1.5	-1.5	0.8	0.3	1.1	0.8	0.4	-0.1	0.9	0.1	1.0
Medication: Bendroflumethiazide	0.5	0.7	3.4	0.5	-1.0	-1.5	0.6	-0.6	-0.7	-1.5	-0.4	-0.6	-0.6	-0.5	-0.6	-0.9	-0.3	-0.4	-0.4	-0.3	-1.1	-1.8	-0.5	-0.9	-0.2	-0.9
Ever smoked	0.5	0.9	4.8	0.0	-0.5	-0.5	2.2	0.6	0.7	-0.7	-0.3	-1.7	0.7	-0.0	0.0	0.2	-1.6	-0.0	-1.4	1.2	0.4	-0.2	0.7	0.5	1.8	0.6
Depression (Nagel 2018)	0.4	0.6	3.4	-0.0	0.8	0.5	-1.8	0.2	0.5	-0.1	0.1	-0.3	0.4	0.1	0.2	-1.0	-0.0	0.0	-0.4	0.3	1.5	0.3	-1.2	0.8	-0.1	1.4
Neuroticism (Nagel 2018)	0.4	1.0	8.6	-1.0	-0.1	-0.3	-2.9	-0.4	0.7	0.7	-0.8	-1.7	0.5	-0.0	0.0	-0.0	-0.8	-1.1	-0.7	-0.5	1.1	-1.2	-1.0	1.0	0.1	1.3
Crohns Disease (2017)	0.4	1.0	3.0	0.4	-0.9	-0.7	-0.5	-1.0	-1.2	0.9	-0.9	-1.1	-1.1	-1.4	-1.1	0.4	0.1	-0.8	-0.4	-0.6	-1.4	-0.6	0.6	-1.5	-1.6	-1.7
HbA1C	0.4	0.5	1.9	-0.2	-0.3	-0.8	-1.3	-1.3	-0.7	0.5	0.4	-0.8	-0.2	-0.7	-0.5	0.3	-0.9	-0.5	-0.0	0.0	0.3	-1.4	-0.5	-0.2	-1.1	-0.1
Neuroticism	0.4	1.0	4.4	0.4	0.5	-0.2	-2.1	-1.4	-0.2	0.1	-0.1	-1.9	-0.4	-1.0	-1.0	0.5	-0.5	-1.0	-0.8	0.2	0.6	-1.7	-1.8	0.2	-0.1	0.8
Frequency of depressed mood in last 2 weeks	0.4	0.6	3.5	0.7	0.1	0.3	-1.9	-0.9	-0.0	-1.0	-0.8	-0.5	-0.3	-1.1	-0.4	0.1	-0.6	-1.0	-1.2	0.0	0.5	-0.3	-0.8	0.2	0.2	0.8
Angina	0.4	0.6	2.3	0.4	-1.5	-0.5	-0.7	-0.9	-0.6	0.1	1.4	-1.0	-0.7	-0.7	-0.8	0.0	-0.9	-0.2	-0.5	-0.2	-0.5	-1.2	-0.7	-0.5	-1.0	-0.4
Vitamin and mineral supplements	0.4	0.6	2.6	0.5	-0.6	0.4	0.6	1.3	0.5	1.2	-0.5	-0.6	0.5	0.9	0.4	0.1	-0.7	0.9	1.1	0.5	0.6	-0.0	1.6	0.5	0.5	-0.1
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	5.4	-0.5	0.3	-0.2	2.3	0.4	0.3	-0.0	0.5	0.1	0.4	-0.2	0.2	0.4	0.3	0.7	1.2	0.5	0.1	0.5	-0.3	0.0	0.5	0.1
High blood pressure	0.4	1.0	4.6	-0.6	0.1	-1.8	-0.0	-1.3	-0.6	-1.0	-0.8	0.4	-0.8	-0.9	-0.8	-2.1	-0.8	-1.2	-0.1	0.7	-0.6	-2.1	-0.9	-0.4	0.3	-0.1
Medication: Atenolol	0.4	0.5	2.6	-0.4	-0.3	-0.3	-1.2	-0.6	-0.1	-0.3	1.0	-0.5	-0.1	-0.4	-0.3	1.0	-0.2	-0.3	-1.3	1.6	0.5	-1.5	-0.4	0.3	-0.2	0.3
Impedance of leg (left)	0.4	1.8	13.9	-3.7	-0.2	-0.9	-2.8	0.3	0.8	2.3	-1.0	-1.5	0.6	0.1	0.3	1.3	-1.9	-0.8	0.9	0.8	-0.4	-0.5	-0.8	0.4	0.4	1.1
Number of incorrect matches in round	0.4	0.6	3.2	-0.3	0.8	0.8	-0.9	0.4	-0.2	-0.2	-0.4	0.2	0.0	0.6	0.7	1.2	1.6	0.9	0.9	1.2	0.1	1.8	-0.6	0.2	-0.5	0.2
Ever unenthusiastic/disinterested for a whole week	0.4	0.4	1.8	-1.0	1.0	-0.6	-0.7	0.4	0.3	0.9	-0.3	0.6	0.2	0.2	0.4	-0.7	-0.3	-0.1	1.4	0.7	0.9	0.2	-0.2	0.6	-0.1	1.0
Exposure to tobacco smoke at home	0.4	0.4	1.8	-0.4	1.3	0.9	-0.5	0.6	0.3	0.4	-0.4	0.3	0.5	0.1	0.5	-1.2	0.6	1.0	0.3	1.2	0.2	0.9	0.3	0.2	0.5	0.0
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	2.6	-0.5	0.5	0.4	1.3	0.9	0.9	-0.8	1.4	-0.9	1.0	0.9	1.0	-0.2	0.3	0.9	0.1	-0.7	0.8	0.4	0.5	1.0	1.6	0.9
Medication: Amlodipine	0.4	0.5	2.7	0.8	0.2	-0.5	-0.7	-0.4	-0.6	-0.1	-1.0	1.7	-0.4	-0.3	0.0	-0.7	-0.4	-0.7	-1.6	-0.3	-0.7	-1.0	-0.4	-0.5	-0.6	-0.1
Number of full brothers	0.4	0.5	3.6	-0.7	-0.2	0.8	0.2	0.4	0.4	-0.6	0.8	0.7	0.6	0.4	0.4	-1.1	-0.7	0.2	1.9	0.5	0.6	0.7	-0.2	0.7	0.8	1.0
Worry too long after embarrassment	0.4	0.7	5.4	0.1	-0.6	-0.6	-0.4	-0.1	-0.3	0.0	-0.5	-1.9	-0.3	0.2	-0.7	-0.5	-2.3	-1.0	-0.1	-0.4	0.2	-1.7	-0.4	0.3	-1.2	0.4
Age at first live birth	0.4	0.7	4.6	0.4	-2.1	-0.2	-1.3	-0.4	-0.0	1.8	0.1	-0.2	-0.2	0.4	-0.4	0.4	-0.3	-0.7	0.1	-0.3	0.1	-1.1	1.4	-0.1	-0.8	-0.7
Medication: Blood pressure	0.4	0.7	3.7	-1.0	0.0	-0.6	-0.6	-0.0	0.3	1.9	-0.3	1.2	0.2	-0.1	0.3	-1.5	-0.5	0.0	1.9	0.5	-0.0	-0.7	-0.8	0.1	0.6	0.5
Angina (self-reported)	0.4	0.5	2.3	0.3	-1.5	-0.5	-0.6	-0.8	-0.5	0.3	1.5	-0.9	-0.7	-0.6	-0.7	0.0	-0.9	-0.0	-0.5	-0.1	-0.5	-1.1	-0.5	-0.4	-1.0	-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.9	0.8	-0.0	0.1	-1.4	-0.6	0.5	1.0	-1.0	-0.3	0.1	-0.0	0.4	-0.6	-0.7	-1.0	-0.8	0.4	0.8	-0.2	1.3	0.3	0.4	0.1
Family relationship satisfaction	0.4	0.5	2.1	-0.1	-0.1	1.4	0.1	-0.4	-0.4	0.9	-0.7	1.3	-0.3	-0.3	-0.2	0.6	0.6	-0.1	1.4	-1.1	0.0	1.2	0.5	-0.1	-1.1	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	3.1	-0.4	-0.0	-0.6	-0.2	0.0	0.3	0.2	1.8	-1.6	0.1	-0.3	-0.2	0.8	-0.9	-0.7	-0.9	0.6	0.2	0.4	0.5	0.3	0.8	0.3
Smoking status: Previous	0.4	0.6	4.4	-0.7	-0.7	-0.2	0.8	-0.3	0.4	0.3	-0.2	-1.3	0.2	-0.1	-0.1	-0.1	-1.5	-0.8	-2.1	0.6	0.1	0.2	-0.0	0.5	0.7	0.9
Number of self-reported non-cancer illnesses	0.4	0.6	2.5	-0.7	-0.1	-1.1	-1.3	-0.4	0.6	0.2	0.6	-0.5	0.4	0.2	0.3	-1.6	-1.0	-0.4	-0.4	1.3	0.4	-1.4	-0.1	0.8	0.4	1.0
Tinnitus: Yes, now most or all of the time	0.4	0.4	2.5	0.1	0.3	0.4	0.3	0.1	0.2	0.4	0.8	0.3	0.0	0.6	0.3	-1.3	-1.3	-0.3	1.6	-0.3	0.0	0.9	0.4	0.4	-0.3	0.6
Irritability	0.4	0.7	2.1	1.0	0.0	-0.4	-1.4	-1.1	-0.5	0.3	-1.1	-1.1	-0.6	-1.0	-0.8	-0.1	-0.4	-1.3	-1.3	-0.7	-0.5	-1.3	-0.7	-0.5	0.3	-0.1
Vascular/heart problems diagnosed by doctor	0.4	1.2	4.6	0.2	-0.2	1.7	0.4	1.7	1.0	0.9	1.0	-0.6	1.2	1.4	1.1	2.1	0.6	1.0	0.2	-1.0	0.7	2.1	1.2	0.7	0.0	0.4
Pack years of smoking	0.4	0.6	3.3	-1.2	0.9	0.9	0.5	0.3	0.6	-1.4	-0.8	0.1	0.4	0.1	0.3	1.8	1.1	0.9	1.1	-0.7	0.6	0.2	0.0	0.5	0.2	0.0
Bipolar Disorder (2011)	0.3	0.3	1.5	-0.0	1.0	-0.1	-1.2	-0.9	-0.3	0.8	-0.8	0.6	-0.3	-0.6	-0.5	0.0	0.3	-0.7	0.0	0.1	0.4	-0.6	-0.5	-0.2	-0.1	0.0
Mean Putamen Volume	0.3	0.3	1.4	-0.8	0.4	-0.2	0.1	0.2	-0.0	-0.1	-0.6	-0.5	0.0	-0.1	-0.1	-0.8	0.3	0.6	0.8	0.8	0.5	0.8	-1.2	0.1	0.7	0.2
Lupus	0.3	0.5	2.7	1.0	-0.8	-0.4	1.6	-0.1	-0.2	-0.5	-0.2	-0.5	-0.3	-0.6	-0.8	-0.8	-1.5	-0.0	-0.9	0.6	-0.1	-0.8	0.5	-0.1	-0.1	-0.0
Hearing difficulty/problems: Yes	0.3	0.5	4.2	-0.9	1.0	0.0	-0.6	0.0	-0.3	1.1	-0.0	0.4	-0.3	-0.1	-0.1	-1.3	-0.1	0.1	0.1	0.6	-0.3	0.4	2.0	-0.1	-0.6	-0.7
Medication: Co-codamol	0.3	0.4	1.6	-1.0	0.2	0.1	-0.2	0.4	0.5	0.7	0.5	-0.5	0.6	0.6	0.6	1.3	0.6	0.7	1.2	0.5	0.2	-0.8	-0.4	0.5	-0.0	0.1
Current tobacco smoking	0.3	0.6	2.8	0.1	-0.5	-0.8	-0.1	-0.2	-0.7	-0.8	-1.1	-0.3	-0.7	-0.9	-0.7	0.4	0.4	0.1	0.9	-0.4	-1.4	0.0	0.2	-1.3	0.2	-1.7
Taking other prescription medications	0.3	0.5	2.1	-0.3	-0.6	-0.8	-0.0	-0.3	0.3	-0.2	0.1	0.0	0.2	-0.9	0.1	-0.7	-1.3	-1.0	-0.3	-0.8	0.2	-1.5	0.0	0.6	1.5	1.2
Qualifications: CSEs or equivalent	0.3	0.3	1.8	0.2	0.1	0.3	-1.3	-1.2	-0.4	-0.6	-0.4	0.2	-0.5	-0.5	-0.1	0.0	0.5	-1.0	-0.6	-0.3	0.0	0.6	-0.9	-0.4	-0.2	-0.1
Serious illness, injury or assault to yourself	0.3	0.4	2.2	0.3	-0.2	-0.9	0.6	0.2	0.1	1.2	0.6	0.6	0.1	-0.3	-0.2	-1.5	-1.2	-0.2	-0.6	1.0	0.1	-0.5	0.2	-0.1	0.7	0.1
Multivitamins +/- minerals	0.3	0.4	3.1	-0.2	0.8	-0.4	-0.8	-1.0	-0.4	-0.3	0.2	0.0	-0.4	-0.6	-0.4	-0.2	0.4	-0.9	-1.8	0.2	-0.6	0.2	-1.0	-0.4	-0.2	0.0
Sitting height	0.3	2.5	19.5	2.6	0.5	1.2	1.1	-0.1	-0.8	4.4	-0.9	1.6	-0.6	-0.2	-0.4	-0.3	0.6	1.1	0.7	-0.6	-0.2	-0.4	3.7	-0.7	-1.6	-1.8
Past tobacco smoking	0.3	0.6	3.6	0.3	0.7	0.1	-1.4	-0.0	-0.5	-0.3	0.3	1.2	-0.4	-0.0	-0.0	-0.1	1.4	0.4	1.9	-0.7	0.0	-0.2	-0.8	-0.4	-1.3	-0.5
Hearing difficulty/problems with background noise	0.3	0.5	3.4	-0.3	-0.2	-0.3	-1.1	0.1	0.1	1.0	-0.7	-0.6	0.0	-0.3	-0.2	-1.1	-1.5	-0.3	0.5	-0.7	0.0	-0.9	1.9	0.4	0.2	-0.1
Forced vital capacity (FVC)	0.3	1.3	6.0	-0.9	0.4	1.5	1.3	1.4	0.9	2.4	0.8	-1.0	1.0	1.4	0.9	-0.9	-0.2	1.7	0.9	-0.4	1.6	0.5	1.5	1.2	-0.1	0.6
Mouth/teeth dental problems	0.3	0.5	2.7	-1.3	-0.9	-0.8	-1.6	0.1	0.4	0.1	0.5	-1.1	0.3	0.7	0.1	-1.0	-0.3	-0.3	0.4	-0.3	0.5	-0.2	-0.3	0.7	-0.4	0.8
Happiness	0.3	0.4	1.8	0.8	0.7	0.8	1.0	0.1	-0.1	1.3	-0.0	0.7	-0.1	0.1	-0.5	0.2	-0.2	0.6	0.5	0.8	0.6	0.4	0.3	0.2	-1.0	0.2
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	2.9	1.2	0.3	0.7	-0.0	0.5	0.5	0.5	0.1	-0.9	0.4	0.9	0.5	1.0	-0.3	0.0	-0.1	0.8	0.4	-0.1	1.7	0.4	0.5	-0.1
Forced vital capacity (FVC), Best measure	0.3	1.0	3.5	-1.2	-0.6	1.1	1.3	0.9	0.8	1.5	0.9	-1.9	0.8	1.0	0.3	-0.0	-1.0	1.3	1.4	-0.8	1.3	0.1	0.8	1.1	-0.0	0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	1.9	-0.8	0.0	-0.0	-0.3	0.5	0.5	-0.6	-0.4	0.4	0.5	0.4	0.4	0.0	0.7	0.4	-0.6	1.4	0.9	0.5	-0.9	0.6	0.2	0.8
Handedness (chirality/laterality): Left-handed	0.3	0.4	2.2	0.2	-0.6	-0.0	1.5	-0.1	-0.2	1.3	0.7	-0.9	-0.1	-0.0	-0.2	0.7	-0.9	-0.2	0.7	0.6	0.1	0.2	0.7	0.0	-0.3	0.1
Mood swings	0.3	0.5	3.6	1.2	1.3	0.6	-1.9	-0.7	0.2	0.3	-0.2	0.6	-0.0	-0.2	-0.0	1.3	0.4	-0.4	-1.1	-0.1	0.3	-0.3	-0.6	0.3	0.3	0.3
Loneliness, isolation	0.3	0.5	4.7	-0.7	-0.8	-0.4	-2.2	-0.3	-0.5	0.3	-0.9	0.3	-0.5	-0.1	-0.4	-0.9	-0.1	-0.2	0.3	-0.3	-0.4	-0.7	0.1	-0.3	-0.8	-0.6
Smoking status: Current	0.3	0.4	3.4	-0.4	-0.1	-0.0	0.4	0.6	0.1	-0.6	-0.9	0.2	0.1	-0.1	0.1	0.2	0.6	0.8	1.8	0.0	-0.8	0.8	0.6	-0.5	0.9	-0.9
Average weekly champagne plus white wine intake	0.3	0.4	2.0	-0.2	0.1	1.3	0.6	0.3	0.6	-1.4	-0.7	-0.4	0.4	0.2	0.7	1.1	0.8	0.7	0.3	1.0	0.5	0.0	0.4	0.5	-0.2	0.3
Miserableness	0.3	0.5	2.8	-0.5	1.5	1.7	-1.2	-0.0	0.6	0.5	0.8	0.1	0.4	0.2	0.6	0.1	0.3	-0.1	0.9	0.4	0.5	0.1	-0.7	0.7	0.8	1.0
Mother’s age at death	0.3	0.4	3.2	0.3	-0.4	0.2	-0.5	0.6	0.2	1.8	1.0	0.7	0.3	0.5	0.3	-0.1	-0.0	1.2	-0.2	0.5	0.2	0.4	-0.2	0.2	0.0	0.1
Number of operations (self-reported)	0.3	0.5	1.7	0.1	-0.8	-0.4	-1.2	-0.3	0.8	-0.0	0.0	0.2	0.5	0.1	0.3	-1.3	-1.0	-0.4	0.0	0.8	1.0	-0.8	-0.6	0.9	0.9	1.2
Fractured/broken bones in last 5 years	0.3	0.4	1.8	1.0	0.9	0.6	0.9	-0.2	0.3	0.3	0.4	0.8	0.3	-0.1	0.4	0.7	-0.1	0.2	-1.3	1.1	0.1	-0.8	1.1	0.2	0.8	-0.0
Ever depressed for a whole week	0.3	0.4	1.3	-0.6	0.4	-0.8	-1.1	-0.2	0.2	-0.6	-0.4	-1.0	0.1	-0.4	-0.2	-0.5	-1.1	-1.0	-0.1	1.2	0.8	0.1	-0.5	0.5	0.1	1.0
Depressed Affect (Nagel 2018)	0.2	0.4	5.9	-0.4	0.3	0.6	-2.4	-0.5	0.3	0.6	-0.3	-0.1	0.0	-0.0	0.1	0.7	0.0	-0.6	-0.0	-0.5	0.5	-0.1	-0.5	0.5	-0.2	0.4
Fed-up feelings	0.2	0.4	2.2	0.2	1.5	1.0	-1.4	-0.4	0.0	1.0	0.1	-0.0	-0.1	-0.1	0.2	0.8	1.0	-0.1	-0.4	0.2	0.1	0.6	-0.0	0.1	-0.1	-0.1
Pain all over the body in last month	0.2	0.2	0.9	0.5	0.9	0.7	0.6	-0.2	0.0	-0.8	-0.2	0.8	-0.2	0.2	-0.2	0.0	0.7	0.2	0.3	-1.0	0.5	0.0	0.3	0.3	-0.2	0.2
Prospective memory result	0.2	0.3	1.3	0.1	-0.6	-0.2	-0.1	0.3	0.3	-1.2	-0.8	0.7	0.3	0.3	0.5	1.1	-0.7	0.1	0.4	0.5	-0.2	-0.4	-0.5	0.2	0.6	0.3
Length of working week for main job	0.2	0.3	1.4	-0.3	-0.2	0.6	0.2	-0.4	-0.1	-0.7	0.6	0.6	-0.1	-0.7	-0.3	0.7	-0.1	-1.0	-0.3	-0.7	-0.1	0.2	-1.2	-0.1	0.4	0.4
Wheeze or whistling in the chest in last year	0.2	0.3	2.7	-0.6	-0.1	-0.4	-0.2	0.2	-0.1	0.2	-1.7	-0.3	-0.1	0.1	-0.0	-0.8	-0.5	-0.8	0.6	0.4	-0.3	-0.8	1.0	0.1	0.2	0.0
Qualifications: College or University degree	0.2	0.7	3.3	1.2	-1.2	0.1	0.9	0.7	0.4	0.5	1.6	-0.7	0.3	0.6	-0.4	-1.5	-1.8	0.3	-0.5	0.5	0.5	-0.5	1.3	0.6	-0.2	0.2
Neck or shoulder pain in last month	0.2	0.3	1.7	-0.5	-0.3	-0.5	-0.4	-0.4	0.0	0.2	-0.9	-0.7	0.1	0.0	0.2	0.6	-0.6	-1.3	-0.4	-0.4	-0.7	-0.1	0.7	0.1	0.3	0.0
Overall health rating	0.2	0.5	2.3	0.7	1.5	1.1	0.1	-0.4	-0.2	0.1	0.3	1.1	-0.2	-0.2	0.0	-1.0	1.0	0.2	1.5	0.1	0.1	0.4	0.6	-0.0	-0.2	-0.3
Chest pain or discomfort	0.2	0.3	1.8	0.7	0.1	0.5	0.6	0.2	0.1	0.1	1.3	-0.7	0.1	0.1	-0.1	-1.3	-0.5	0.1	0.4	1.2	0.1	-0.3	0.4	0.2	-0.1	0.2
Ever had bowel cancer screening	0.2	0.3	1.0	0.0	-0.7	-0.5	-0.3	0.5	0.1	0.1	0.3	1.0	0.2	0.0	0.5	-0.4	-0.8	0.6	-0.7	1.0	0.2	-0.2	0.4	0.4	-0.1	0.6
Friendships satisfaction	0.2	0.3	1.5	0.7	-0.2	0.4	-0.7	-0.4	-0.4	0.5	-0.1	1.2	-0.5	-0.4	-0.6	-0.1	-1.1	0.0	-0.6	0.3	-0.2	-0.4	-0.4	-0.3	-0.9	-0.1
Smoking Status	0.1	0.3	1.7	-1.1	-0.8	-0.5	0.1	0.3	0.4	0.6	-0.7	-0.5	0.3	0.1	0.1	-0.3	-0.4	-0.0	0.6	-0.4	-0.6	0.4	0.7	-0.1	1.3	-0.3
Hair Pigment	0.1	4.0	14.1	0.5	0.9	0.1	-0.8	-2.3	-2.8	1.8	-0.6	3.8	-2.6	-2.4	-1.9	1.1	2.7	-1.0	-0.6	-2.3	-0.9	0.4	-2.0	-2.5	-3.5	-2.0
Tanning	0.1	0.7	4.8	0.2	-2.2	-0.9	1.0	-0.4	-0.5	-0.8	-0.7	-0.4	-0.4	-0.6	-0.3	-0.8	-0.7	-1.0	-1.3	-1.1	-1.1	-0.2	0.5	-0.6	-0.5	-0.7
Age started oral contraceptive pill	0.1	0.2	1.0	-0.4	-0.1	-0.1	0.4	0.3	-0.1	0.4	0.7	0.6	0.1	0.3	0.2	0.3	0.0	0.3	-0.3	-0.6	-0.3	-0.4	1.0	0.2	-0.6	-0.1
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0

Hub : Genes

CCDC92

Models

Trait associations