Best TWAS P=3.34e-09 · Best GWAS P=1.19e-09 conditioned to 0.045
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | COMMD6 | 0.47 | 0.32 | enet | 22 | 0.34 | 1.3e-15 | -5.9 | 5.9 | 3.3e-09 | -0.85 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Thyroid | RP11-173B14.4 | 0.08 | 0.09 | lasso | 2 | 0.06 | 1.3e-05 | -5.9 | -5.9 | 3.4e-09 | 0.86 | 0.01 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | UCHL3 | 0.04 | 0.04 | lasso | 3 | 0.05 | 2.8e-06 | -5.8 | -5.6 | 1.8e-08 | 0.87 | 0.01 | 0.98 | FALSE |