[Hub]/) : Traits : Impedance of whole body :

chr16:49,403,920-50,831,256

Best TWAS P=2.44e-10 · Best GWAS P=3.05e-09 conditioned to 0.243

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland HEATR3 0.33 0.30 lasso 9 0.31 1.3e-11 5.2 -5.3 1.2e-07 -0.83 0.24 0.76 FALSE
2 GTEx Artery Aorta HEATR3 0.41 0.41 enet 62 0.42 5.4e-25 5.2 -6.0 2.4e-09 -0.76 0.23 0.76 FALSE
3 GTEx Artery Aorta RP11-429P3.3 0.15 0.15 lasso 4 0.14 5.6e-08 5.2 -5.5 4.7e-08 -0.87 0.12 0.88 FALSE
4 GTEx Artery Coronary HEATR3 0.30 0.25 lasso 5 0.25 6.0e-09 5.2 -5.2 1.9e-07 -0.81 0.19 0.80 FALSE
5 GTEx Artery Tibial RP11-429P3.3 0.09 0.05 lasso 3 0.04 5.9e-04 5.0 -5.1 2.8e-07 -0.74 0.15 0.59 FALSE
6 GTEx Brain Caudate basal ganglia HEATR3 0.36 0.14 lasso 12 0.20 2.6e-06 5.1 -5.4 8.3e-08 -0.80 0.22 0.70 FALSE
7 GTEx Brain Cortex HEATR3 0.51 0.46 lasso 11 0.47 8.5e-15 5.2 -5.6 1.7e-08 -0.81 0.23 0.77 FALSE
8 GTEx Brain Frontal Cortex BA9 HEATR3 0.30 0.20 lasso 10 0.16 5.6e-05 5.1 -5.5 5.1e-08 -0.81 0.18 0.53 FALSE
9 GTEx Brain Putamen basal ganglia HEATR3 0.27 0.16 lasso 6 0.15 2.3e-04 5.2 -5.1 3.0e-07 -0.81 0.05 0.66 FALSE
10 GTEx Cells Transformed fibroblasts HEATR3 0.22 0.18 lasso 15 0.20 1.4e-14 5.9 -5.9 4.6e-09 -0.97 0.01 0.99 FALSE
11 GTEx Colon Transverse HEATR3 0.36 0.36 lasso 7 0.36 9.1e-18 5.1 -5.1 2.9e-07 -0.83 0.28 0.72 FALSE
12 GTEx Esophagus Muscularis HEATR3 0.40 0.38 lasso 8 0.39 6.1e-25 5.1 -5.2 2.1e-07 -0.82 0.29 0.71 FALSE
13 GTEx Heart Atrial Appendage HEATR3 0.30 0.30 lasso 8 0.27 1.1e-12 5.2 -5.2 2.2e-07 -0.82 0.22 0.78 FALSE
14 GTEx Lung HEATR3 0.34 0.40 enet 19 0.41 6.4e-34 5.2 -5.5 3.7e-08 -0.83 0.22 0.78 FALSE
15 GTEx Ovary HEATR3 0.30 0.14 lasso 11 0.16 1.2e-04 5.1 -5.4 5.9e-08 -0.87 0.06 0.77 FALSE
16 GTEx Ovary RP11-429P3.3 0.27 0.11 enet 15 0.15 1.9e-04 5.7 -6.3 2.4e-10 -0.84 0.02 0.91 TRUE
17 GTEx Pancreas HEATR3 0.37 0.20 lasso 10 0.24 2.1e-10 5.1 -5.2 2.6e-07 -0.84 0.17 0.83 FALSE
18 GTEx Spleen HEATR3 0.43 0.13 lasso 9 0.13 2.7e-04 5.1 -5.5 4.6e-08 -0.80 0.12 0.80 FALSE
19 GTEx Stomach HEATR3 0.36 0.27 enet 14 0.28 1.6e-13 4.9 -5.2 2.0e-07 -0.77 0.34 0.66 FALSE
20 The Cancer Genome Atlas Glioblastoma Multiforme HEATR3 0.13 0.07 blup 39 0.10 5.1e-04 5.2 -6.2 4.3e-10 -0.84 0.02 0.84 FALSE
21 The Cancer Genome Atlas Thyroid Carcinoma PAPD5 0.02 0.03 lasso 1 0.02 1.8e-03 5.4 -5.4 7.8e-08 -0.39 0.01 0.89 FALSE