Best TWAS P=7.21e-10 · Best GWAS P=4.4e-10 conditioned to 8.96e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | RYK | 0.07 | 0.00 | lasso | 3 | 0.00 | 0.307 | -4.0 | -6.2 | 7.2e-10 | 0.44 | 0.06 | 0.12 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | RYK | 0.09 | 0.01 | blup | 63 | 0.01 | 0.048 | -6.2 | -5.9 | 4.6e-09 | 0.89 | 0.01 | 0.67 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | RYK | 0.03 | 0.01 | blup | 63 | 0.01 | 0.020 | -6.2 | -5.8 | 5.5e-09 | 0.95 | 0.01 | 0.92 | FALSE |