[Hub]/) : Traits : Impedance of whole body :

chr6:41,005,502-42,587,818

Best TWAS P=1.83e-14 · Best GWAS P=3.99e-13 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts MED20 0.11 0.05 lasso 4 0.08 9.4e-07 6.9 -6.8 8.0e-12 -0.81 0.01 0.99 FALSE
2 GTEx Cells Transformed fibroblasts USP49 0.13 0.02 lasso 4 0.02 2.4e-02 7.3 6.6 3.9e-11 0.93 0.01 0.97 FALSE
3 GTEx Lung USP49 0.09 0.08 lasso 2 0.05 6.2e-05 7.3 7.2 4.8e-13 0.99 0.01 0.99 FALSE
4 GTEx Testis MED20 0.13 0.03 lasso 6 0.00 2.0e-01 7.2 -7.1 1.1e-12 -0.99 0.02 0.90 FALSE
5 ROSMAP Brain Pre-frontal Cortex PGC 0.13 0.06 blup 520 0.06 3.2e-08 -5.2 5.4 6.4e-08 0.57 0.99 0.01 FALSE
6 The Cancer Genome Atlas Breast Invasive Carcinoma CCND3 0.04 0.00 blup 99 0.01 1.8e-03 7.2 -6.0 1.9e-09 -0.69 0.01 0.56 FALSE
7 The Cancer Genome Atlas Colon Adenocarcinoma MED20 0.05 0.00 blup 50 0.04 2.8e-03 -2.7 -6.6 3.9e-11 -0.85 0.02 0.74 FALSE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma MED20 0.04 0.03 lasso 3 0.04 7.3e-05 6.9 -7.0 2.9e-12 -0.97 0.01 0.99 FALSE
9 The Cancer Genome Atlas Liver Hepatocellular Carcinoma MED20 0.09 0.07 lasso 5 0.07 3.4e-04 7.2 -7.7 1.8e-14 -0.99 0.01 0.98 TRUE
10 The Cancer Genome Atlas Stomach Adenocarcinoma MED20 0.03 0.05 lasso 2 0.04 1.2e-03 6.9 -7.4 1.7e-13 -0.96 0.01 0.92 FALSE