Best TWAS P=4.22e-09 · Best GWAS P=3.03e-13 conditioned to 2.09e-16
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells EBV-transformed lymphocytes | SUN1 | 0.27 | 0.00 | lasso | 7 | 0.00 | 4.8e-01 | 3.5 | 5.9 | 4.2e-09 | -0.14 | 0.06 | 0.08 | TRUE |
| 2 | GTEx | Skin Not Sun Exposed Suprapubic | RP11-449P15.2 | 0.10 | 0.07 | lasso | 2 | 0.07 | 7.2e-05 | -4.7 | -5.3 | 1.3e-07 | 0.14 | 0.26 | 0.05 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | GPR146 | 0.03 | 0.04 | lasso | 4 | 0.04 | 5.8e-05 | -4.9 | 5.2 | 2.6e-07 | -0.03 | 0.02 | 0.96 | FALSE |