TWAS
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Usage
Models
Genes
Traits
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Traits
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Impedance of whole body
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chr7:511,203-1,618,854
Best TWAS P=4.22e-09 · Best GWAS P=3.03e-13 conditioned to 2.09e-16
0.6M
0.8M
1M
1.2M
1.4M
1.6M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells EBV-transformed lymphocytes
SUN1
0.27
0.00
lasso
7
0.00
4.8e-01
3.5
5.9
4.2e-09
-0.14
0.06
0.08
TRUE
2
GTEx
Skin Not Sun Exposed Suprapubic
RP11-449P15.2
0.10
0.07
lasso
2
0.07
7.2e-05
-4.7
-5.3
1.3e-07
0.14
0.26
0.05
FALSE
3
The Cancer Genome Atlas
Brain Lower Grade Glioma
GPR146
0.03
0.04
lasso
4
0.04
5.8e-05
-4.9
5.2
2.6e-07
-0.03
0.02
0.96
FALSE