Best TWAS P=8.47e-09 · Best GWAS P=4.41e-06 conditioned to 0.0664
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue | RASA4DP | 0.27 | 0.10 | enet | 33 | 0.08 | 6.2e-05 | 4.5 | -5.8 | 8.5e-09 | -0.53 | 0.01 | 0.88 | TRUE |
| 2 | GTEx | Esophagus Muscularis | RASA4DP | 0.33 | 0.01 | enet | 42 | 0.18 | 3.9e-11 | 4.2 | -5.4 | 6.4e-08 | -0.40 | 0.01 | 0.71 | FALSE |
| 3 | GTEx | Lung | RASA4DP | 0.27 | 0.00 | enet | 42 | 0.01 | 5.5e-02 | 2.1 | -5.4 | 6.8e-08 | -0.34 | 0.00 | 0.06 | FALSE |
| 4 | GTEx | Nerve Tibial | RASA4DP | 0.29 | 0.04 | enet | 37 | 0.11 | 3.0e-08 | 3.1 | -5.2 | 2.3e-07 | -0.43 | 0.01 | 0.50 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | LRWD1 | 0.02 | 0.01 | lasso | 3 | 0.02 | 9.8e-04 | 4.4 | 5.2 | 1.7e-07 | 0.70 | 0.00 | 0.30 | FALSE |
| 6 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | LRWD1 | 0.14 | 0.09 | blup | 24 | 0.06 | 1.3e-02 | 4.2 | 5.3 | 1.5e-07 | 0.90 | 0.00 | 0.14 | FALSE |