Best TWAS P=5.63e-08 · Best GWAS P=7.65e-09 conditioned to 0.0489
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cortex | GCC1 | 0.22 | 0.13 | lasso | 5 | 0.05 | 1.9e-02 | -4.8 | 5.2 | 2.4e-07 | -0.73 | 0.19 | 0.26 | FALSE |
| 2 | METSIM | Adipose | SND1 | 0.06 | 0.03 | blup | 602 | 0.04 | 1.5e-06 | 2.9 | -5.3 | 1.1e-07 | 0.68 | 0.56 | 0.44 | FALSE |
| 3 | YFS | Blood | GCC1 | 0.03 | 0.04 | lasso | 6 | 0.04 | 1.8e-12 | -4.8 | 5.4 | 6.1e-08 | -0.84 | 0.61 | 0.39 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | LRRC4 | 0.02 | 0.03 | lasso | 2 | 0.02 | 2.7e-03 | -5.5 | 5.4 | 5.6e-08 | -0.94 | 0.01 | 0.91 | TRUE |