Best TWAS P=2.5e-28 · Best GWAS P=1.59e-28 conditioned to 3.67e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | MMP16 | 0.12 | 0.07 | lasso | 4 | 0.08 | 4.3e-09 | 11.0 | 7.0 | 2.0e-12 | 0.80 | 0.00 | 1.00 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | MMP16 | 0.10 | 0.08 | blup | 131 | 0.05 | 1.3e-03 | 10.9 | 8.9 | 8.6e-19 | 0.79 | 0.01 | 0.98 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | MMP16 | 0.04 | 0.02 | lasso | 3 | 0.03 | 6.3e-05 | 8.1 | 6.8 | 1.4e-11 | 0.79 | 0.01 | 0.95 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | MMP16 | 0.07 | 0.05 | blup | 133 | 0.04 | 1.7e-05 | 6.8 | 5.5 | 3.4e-08 | 0.74 | 0.02 | 0.97 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | MMP16 | 0.10 | 0.09 | lasso | 4 | 0.08 | 2.9e-08 | 11.0 | 11.0 | 2.5e-28 | 0.85 | 0.01 | 0.99 | TRUE |