Best TWAS P=9.93e-08 · Best GWAS P=5.3e-08 conditioned to 0.00699
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | ROSMAP | Brain Pre-frontal Cortex | RP11-267M23.4 | 0.08 | 0.04 | bslmm | 446 | 0.03 | 2.4e-05 | 5.1 | 5.3 | 1.5e-07 | -0.46 | 0.04 | 0.96 | FALSE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | KIAA1429 | 0.10 | 0.05 | blup | 57 | 0.08 | 4.1e-08 | 5.1 | -5.3 | 9.9e-08 | 0.63 | 0.03 | 0.97 | TRUE |