[Hub]/) : Traits : Impedance of leg (right) : ← →

chr8:101,232,701-102,664,291

Best TWAS P=2.06e-08 · Best GWAS P=4.07e-08 conditioned to 0.469

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
19	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	YWHAZ	0.07	0.07	blup	50	0.08	7.7e-09	5.4	5.6	2.1e-08	0.93	0.01	0.99	TRUE
16	GTEx	Whole Blood	YWHAZ	0.11	0.06	enet	12	0.06	1.7e-06	5.4	5.5	3.1e-08	0.90	0.01	0.99	FALSE
18	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	YWHAZ	0.03	0.04	lasso	2	0.03	1.2e-04	5.5	5.5	4.2e-08	1.00	0.01	0.99	FALSE
7	GTEx	Esophagus Gastroesophageal Junction	YWHAZ	0.35	0.21	lasso	4	0.18	6.0e-07	5.5	5.5	4.7e-08	1.00	0.01	0.99	FALSE
8	GTEx	Esophagus Mucosa	YWHAZ	0.34	0.40	lasso	6	0.41	5.4e-29	5.5	5.4	5.6e-08	1.00	0.01	0.99	FALSE
5	GTEx	Breast Mammary Tissue (Female)	YWHAZ	0.27	0.00	enet	6	0.02	7.3e-02	5.4	5.4	5.8e-08	1.00	0.01	0.82	FALSE
6	GTEx	Colon Transverse	YWHAZ	0.33	0.23	enet	11	0.25	2.0e-12	5.4	5.4	5.9e-08	0.97	0.01	0.99	FALSE
15	GTEx	Thyroid	YWHAZ	0.26	0.21	lasso	5	0.22	1.9e-16	5.3	5.4	6.8e-08	0.99	0.01	0.99	FALSE
3	GTEx	Brain Frontal Cortex BA9	YWHAZ	0.40	0.18	lasso	6	0.16	5.2e-05	5.4	5.4	7.6e-08	0.94	0.01	0.98	FALSE
4	GTEx	Breast Mammary Tissue	YWHAZ	0.16	0.17	lasso	1	0.15	4.4e-08	5.4	5.4	7.7e-08	1.00	0.01	0.99	FALSE
10	GTEx	Heart Atrial Appendage	YWHAZ	0.25	0.22	lasso	3	0.20	1.4e-09	5.4	5.4	7.7e-08	1.00	0.01	0.99	FALSE
9	GTEx	Esophagus Muscularis	YWHAZ	0.43	0.42	lasso	3	0.42	4.6e-27	5.3	5.4	7.8e-08	1.00	0.01	0.99	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	YWHAZ	0.23	0.20	bslmm	465	0.20	2.6e-25	5.4	5.4	8.3e-08	0.98	0.01	0.99	FALSE
12	GTEx	Nerve Tibial	YWHAZ	0.34	0.43	lasso	3	0.44	6.9e-34	5.4	5.4	8.6e-08	1.00	0.01	0.99	FALSE
2	GTEx	Artery Tibial	YWHAZ	0.29	0.30	lasso	5	0.33	6.2e-27	5.3	5.3	1.1e-07	0.99	0.01	0.99	FALSE
14	GTEx	Skin Not Sun Exposed Suprapubic	YWHAZ	0.13	0.07	lasso	3	0.05	8.0e-04	5.3	5.3	1.4e-07	0.98	0.01	0.98	FALSE
11	GTEx	Lung	YWHAZ	0.20	0.22	lasso	4	0.22	1.3e-16	5.4	5.3	1.5e-07	0.99	0.01	0.99	FALSE
13	GTEx	Prostate	YWHAZ	0.30	0.06	lasso	4	0.09	2.5e-03	5.4	5.2	1.7e-07	0.86	0.01	0.90	FALSE
1	GTEx	Adipose Visceral Omentum	YWHAZ	0.20	0.16	lasso	4	0.16	9.2e-09	5.2	5.2	2.1e-07	0.98	0.01	0.99	FALSE