TWAS
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Traits
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Impedance of leg (right)
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chr8:144,465,285-146,011,111
Best TWAS P=1.03e-07 · Best GWAS P=4.09e-08 conditioned to 0.0603
144.4M
144.6M
144.8M
145M
145.2M
145.4M
145.6M
145.8M
146M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Brain Frontal Cortex BA9
KIAA1875
0.16
0.0
lasso
4
0.03
0.05850
5.5
5.3
1.0e-07
0.84
0.02
0.60
TRUE
1
GTEx
Brain Cerebellar Hemisphere
MROH1
0.22
0.2
lasso
4
0.15
0.00011
5.0
5.1
2.9e-07
0.86
0.01
0.93
FALSE