Best TWAS P=7.1e-08 · Best GWAS P=2.39e-08 conditioned to 1.44e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | RPP25L | 0.10 | 0.09 | enet | 10 | 0.05 | 8.5e-04 | 5.1 | 5.1 | 2.6e-07 | -0.32 | 0.03 | 0.96 | FALSE |
| 2 | GTEx | Stomach | RP11-195F19.9 | 0.13 | 0.06 | enet | 15 | 0.11 | 5.0e-06 | 4.0 | -5.4 | 7.1e-08 | 0.26 | 0.11 | 0.60 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | SIGMAR1 | 0.25 | 0.16 | enet | 27 | 0.19 | 1.2e-23 | 3.5 | -5.2 | 2.3e-07 | 0.17 | 0.43 | 0.19 | FALSE |