Best TWAS P=7.12e-12 · Best GWAS P=1.46e-12 conditioned to 0.0273
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2 | GTEx | Cells Transformed fibroblasts | PLIN2 | 0.08 | 0.02 | lasso | 4 | 0.03 | 1.5e-03 | 6.89 | 6.9 | 7.1e-12 | 0.88 | 0.02 | 0.95 | TRUE |
| 7 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FAM154A | 0.08 | 0.04 | blup | 174 | 0.04 | 4.6e-05 | 6.29 | -6.3 | 2.3e-10 | -0.80 | 0.02 | 0.97 | FALSE |
| 1 | GTEx | Breast Mammary Tissue (Female) | HAUS6 | 0.13 | 0.01 | lasso | 1 | 0.00 | 4.2e-01 | -0.58 | -6.1 | 1.1e-09 | -0.62 | 0.05 | 0.28 | FALSE |
| 5 | The Cancer Genome Atlas | Colon Adenocarcinoma | HAUS6 | 0.05 | 0.04 | lasso | 2 | 0.03 | 5.1e-03 | -5.64 | -5.6 | 2.3e-08 | -0.55 | 0.12 | 0.30 | FALSE |
| 3 | GTEx | Esophagus Muscularis | HAUS6 | 0.22 | 0.09 | lasso | 4 | 0.11 | 4.6e-07 | 4.38 | -5.6 | 2.8e-08 | -0.37 | 0.78 | 0.05 | FALSE |
| 6 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | FAM154A | 0.06 | 0.00 | blup | 174 | 0.01 | 1.3e-01 | 3.70 | -5.3 | 1.0e-07 | -0.45 | 0.20 | 0.12 | FALSE |
| 4 | GTEx | Nerve Tibial | HAUS6 | 0.14 | 0.04 | enet | 22 | 0.08 | 1.9e-06 | 2.80 | -5.3 | 1.1e-07 | -0.43 | 0.41 | 0.57 | FALSE |