Best TWAS P=5.11e-16 · Best GWAS P=1.02e-18 conditioned to 0.000415
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | SLC38A2 | 0.02 | 0.02 | blup | 341 | 0.01 | 0.00581 | 8.2 | -8.1 | 5.1e-16 | -0.90 | 0.03 | 0.94 | TRUE |
2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | SLC38A2 | 0.10 | 0.06 | blup | 30 | 0.05 | 0.00083 | 8.4 | -7.9 | 1.9e-15 | -0.86 | 0.02 | 0.80 | FALSE |
3 | The Cancer Genome Atlas | Soft Tissue Sarcoma | SLC38A2 | 0.06 | 0.01 | blup | 30 | 0.03 | 0.00513 | 8.4 | -7.7 | 1.5e-14 | -0.92 | 0.03 | 0.53 | FALSE |