TWAS
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Traits
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Traits
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Impedance of leg (right)
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chr13:26,008,305-27,492,210
Best TWAS P=2.02e-07 · Best GWAS P=1.5e-22 conditioned to 5.09e-18
26M
26.2M
26.4M
26.6M
26.8M
27M
27.2M
27.4M
0
5
10
15
20
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Brain Cerebellum
RNF6
0.28
0
lasso
9
0.01
0.17
-4.9
-5.2
2e-07
0.28
0.06
0.23
TRUE